FNS> Vol.5 No.2, January 2014

Feeding Study with Bt Corn (MON810: Ajeeb YG) on Rats: Biochemical Analysis and Liver Histopathology

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ABSTRACT

Bt corn MON810: Ajeeb YG produces delta endotoxins in the whole plant due to the genetic modification process. The chemical analysis of this variety showed significant differences from its conventional counterpart Ajeeb. Further, feeding studies on rats were designed to complete assessing the safety of MON810: Ajeeb YG. Three groups of rats (6 males and 6 females rats/group) were fed on control diet, non-Bt corn and Bt corn for 1.5 months and 3 months. After 1.5 months, 3 males and 3 females from each group were sacrificed, and after another 1.5 months, 3 males and 3 females from each group and their offspring were sacrificed. Histopathological examination, blood haematology and serum biochemical analysis were determined. Results indicated significant differences among the tested parameters in the three groups especially Bt group. Severe changes in the liver of Bt group after 3 months were observed.

Cite this paper

E. Abdo, O. Barbary and O. Shaltout, "Feeding Study with Bt Corn (MON810: Ajeeb YG) on Rats: Biochemical Analysis and Liver Histopathology," Food and Nutrition Sciences, Vol. 5 No. 2, 2014, pp. 185-195. doi: 10.4236/fns.2014.52024.

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