Effects of oxygen enriched tent by a new oxygen concentration machine on blood oxygen saturation and heart rate in tibet

Guang-Hao Shen, Kun Wang, Li-Hua Lu, Kang-Ning Xie, Qiao-Ling Xu, Xiao-Ming Wu, Chi Tang, Er-Ping Luo

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DOI: 10.4236/jbise.2011.42019                

Abstract

Many people who live in the low altitude areas are often suffered from hypoxia when they entered the high plateau. This problem may seriously influence the physical and mental state and work efficacy for the travelers and workers. Oxygen enrichment of a small space air at high altitude is considered as a simple way to provide lowlanders enriched oxygen for sleeping and resting, improving work efficiency, so we developed an oxygen concentration machine based on the technology of oxygen enrichment membrane. This paper tested 8 healthy male lowlanders (age 21.63±1.77 yr) who have never exposed to plateau performed an incremental exercise on cycle ergometer at sea-level in order to be used as sea-level controls. Two days later, the same subjects were taken to Lhasa (3700 m) by air and exposed to the plateau, performed the same exercise as they did at sea-level. The next day, all subjects were asked to enter the experimental tent which was enriched with oxygen (higher than 24%) by the oxygen concentration machine and sleep for 10 hours at night, then exposed to plateau and performed the same exercise twice at different time (2 hours and 10 hours after oxygen enrichment). During the tests, subjects must cycled continuously at 60 rpm beginning with a 3 min exercise intensity of 0 W followed by incremental increases of 25 W every 3 min until 150 W, pulse oxygen saturation (SpO2) and heart rate (HR) were recorded. After sleeping in an oxygen enrichment of tent air, 2 hours later, the subjects’ load capacity had no difference compared with control group, but significant difference than before (higher SpO2 and lower HR), which indicated that oxygen concentration machine is effective in increasing the oxygen concentration of the air for the tent and sleeping in the oxygen enrichment tent for l0 h might be effective in improving exercise performance during high-altitude hypoxia. At the same time, 10 hours later, when work-load exceeded 125 W, the same effects were also found. The results indicated the effects of oxygen enrichment of tent air could last a certain period of time.

Keywords

Hypoxia; Oxygen Concentration Machine; Oxygen Enrichment Membrane; High Plateau; Oxygen Enrichment

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	West, J.B. (1986) Highest inhabitants in the world. Nature, 324, 517.
[2]	Wu, T, Kayser, B. (2006) High altitude adaptation in Tibetans. High Altitude Medicine ＆ Biology, 7, 193-208.
[3]	Luks, A.M, van Melick, H., Batarse, R.R., Grant I. and West J.B. (1998). Room oxygen enrichment improves sleep and subsequent day-time performance at high altitude. Respiration Physiology, 113, 247-258.
[4]	Siqués,P. and Brito, J. (2009) Blood Pressure Responses in Young Adults First Exposed to High Altitude for 12 Months at 3550m. High Altitude Medicine＆Biology, 10, 329-335.
[5]	Ha, Z.D., He., T.H., Zhang, X.Z., Wang, W., Ma, Y. and Jian, X.Q. (2004) Effects of oxygen enrichment of room air on sleep patterns at high altitude. Zhonghua Nei Ke Za Zhi, 43, 368-370.
[6]	Sato, M., Severinghaus, J.W., Powell, F.L., Xu, F.D. and Spellman, M.J (1992) Augmented hypoxic ventilatory response in men at altitude. Journal of Applied Physiology, 73, 101-107.
[7]	Sato, M., Severinghaus, J.W. and Bickler, P. (1994) Time course of augmentation and depression of hypoxic ventilatory responses at altitude. Journal of Applied Physiology, 77, 313-316.
[8]	Calbet, J.A. (2003) Chronic hypoxia increases blood pressure and noradrenaline spillover in healthy humans. The Journal of Physiology, 551, 379-386.
[9]	Black, C.P., Tenney, S.M. (1980) Oxygen transport during progressive hypoxia in high-altitude and sea-level waterfowl. Respiration Physiology. 39, 217-239.
[10]	West J.B. (2003) Improving oxygenation at high altitude: acclimatization and O2 enrichment. High Altitude Medicine＆Biology, 4(3): 389-398.
[11]	Fletcher, E.C. (2001) Invited review: physiological consequences of intermittent hypoxia: systemic blood pressure. Journal of Applied Physiology, 90, 1600- 1605.
[12]	West, J.B. (2002) Potential use of oxygen enrichment of room air in mountain resorts. High Altitude Medicine＆Biology, 3, 59-64.
[13]	West, J.B. (1995) Oxygen enrichment of room air to relieve the hypoxia of high altitude. Respiration Physiology, 99, 225-232.
[14]	West, J.B. (2007) Adventures in high-altitude physiology. Advances in Experimental Medicine Biology, 588, 7-16.
[15]	Richard, W.B. (2002) Future Directions of Membrane Gas Separation Technology. Industrial ＆ Engineering Chemistry Research, 41, 1393-1411.
[16]	Rigby, G.R. and Watson, H.C. (1994) Application of membrane gas separation to oxygen enrichment of diesel engines. Journal of Membrane Science, 87, 159-169.
[17]	Byuna, Hongsik., Honga, B. and Lee, B. (2006) The effect of oxygen enriched air obtained by gas separation membranes from the emission gas of diesel engines. Desalination, 193, 73-81
[18]	ASHRAE Standard 90-75. (1975) Energy Conservation in New Building Design, Atlanta, GA: American Society of Heating, Refrigerating, and Air-Conditioning Engineers, Inc.
[19]	Luks, A.M., van Melick H., Batarse R.R., Grant I. and West, J.B. (1998) Room oxygen enrichment improves sleep and subsequent day-time performance at high altitude. Respiration Physiology, 113, 247-258.
[20]	ASHRAE Standard 62-1989. (1989) Ventilation for Acceptable Indoor Air Quality. Atlanta, GA: American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc.
[21]	Cui, J.H., Zhang, X.Z., Zhang, J.L., Zhang, F., Ma, Y. and Wang, D.W. (2003) Effects of enriched oxygen on human free radical metabolism during exercise at 5 380 m plateau. Space Med Med Eng (Beijing), 16, 377-378.