Health> Vol.5 No.9, September 2013

Mortality rates from a Nigerian isolate of the Infectious Bursa Disease Virus and passive haemagglutination antibody titer that protects chicks against challenge with the virus isolate

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ABSTRACT

To determine passive haemagglutination (PHA) antibody titer that would protect chicks against Nigerian isolates of the Infectious Bursa Disease Virus (IBDV), five groups of chicks aged 30 days which had different antibody titers were challenged with a Nigerian isolate of virulent IBDV. Mortality rates of the different groups were plotted against their respective mean PHA antibody titers. A group with zero antibody titer had a mortality rate of 75% while those with PHA antibody titers of 185.6, 243.2, 256 and 307.2 had mortality rates of 40%, zero, zero and zero respectively. Linear equation generated for a line of best fit of the graph of mortality rates of the chicks on their IBD antibody titers gave antibody titer (X) at which mortality (Y) would be zero as 300. A mortality of 75% and the high antibody level needed to protect chicks suggest that the isolate may be a hypervirulent strain.

Cite this paper

Ezeibe, M. , Okoye, J. , Ogunniran, T. , Animoke, P. , Mbuko, I. , Nwankwo, I. and Ngene, A. (2013) Mortality rates from a Nigerian isolate of the Infectious Bursa Disease Virus and passive haemagglutination antibody titer that protects chicks against challenge with the virus isolate. Health, 5, 1355-1359. doi: 10.4236/health.2013.59184.

References

[1] Chou, K.C. and Calnek, B.W. (1997) Diseases of poultry, Iowa state university press. 10th Edition, Ames, Iowa 721-733.
[2] Cosgrove, A.S. (1962) An apparently new disease of chickens-Avian nephrosis. Avian Disease, 6, 385-389. doi:10.2307/1587909
[3] Cho, Y. and Edgar, S.A. (1969) Characterisation of the infectious bursal agent. Poult. Science, 48, 2102-2109. doi:10.3382/ps.0482102
[4] United Kingdom Epidermiological unit, central vet. Lab (1981) Subclinical infectious bursal disease in broiler industry. Interim report. Veterinary Record, 108, 88-89.
[5] Okoye, J.O.A. and Uzoukwu, M. (1981) An outbreak of infectious bursal disease among Chickens between 16 and 20 week old. Avian Disease, 25, 1034-1038. doi:10.2307/1590079
[6] Okoye, J.O.A. (1983) The pathogenecity and pathology of a Nigerian isolate of infectious bursal disease virus in chickens. M. Phil. Diss., University of Nigeria, Nsukka.
[7] Okoye, J.O.A. and Soyinka, S.V.O. (1983) Newcastle disease in a vaccinated flock which had experienced subclinical infections bursal disease. Tropical Animal Health and Production, 15, 221-225. doi:10.1007/BF02242062
[8] Muller, H. (1986) Replication of infectious bursal disease virus in lymphoid cells. Archives of Virology, 87, 191-203. doi:10.1007/BF01315299
[9] Mcllroy, S.G., Goodall, D.W., Bruce, D.W., McCracken, R.M. and McNulty, M.S. (1992) The cost benefit of vaccinating broiler flocks against subclinical infectious bursal disease. Avian Pathology, 21, 65-76. doi:10.1080/03079459208418819
[10] Okoye, J.O.A. and Aba-Adulugba, E.P. (1998) Comparative study of the resistance or susceptibility of local Nigerian chicken and exotic chickens to Infectious bursal Disease. Avian Pathology, 27, 168-173. doi:10.1080/03079459808419319
[11] Helmbolt, C.F. and Garner, E. (1964) Experimentally induced Gumboro disease (IBA). Avian Disease, 8, 561-575. doi:10.2307/1587944
[12] Lensing, H.H (1968) Gumboro disease. Tijdschr. Diergeneesk, 93, 1452-1460.
[13] Maire, C., Renault, L., Alamagny, A., Dreuille, M.D.E. and Albouy, R. (1969) Existence en France de la maladie de Gumboro. Rec med. Vet, 145, 75-84.
[14] Chineme, C.N. (1977) Clinicopathologic and morphologic changes in experimental infectious bursal (Gumboro) disease. Abstracts of papers presented at the 14th Annual conference of the Nigerian Veterinary Medical Association. Journal of Nigerian Veterinary Medical Association, 61, 46.
[15] Hirai, K.K., Kunihiro and Shimakura, S. (1979) Characterization of immunosuppressionin chickens by infectious bursal disease virus. Avian Disease, 23, 950-965. doi:10.2307/1589611
[16] Delegation of the United States of America (1977) Infectious bursal disease (Gumbro) Field incidence in the United States. Bulletin de l Office International des Epizooties, 88, 313-322.
[17] Gyening, K.O. and Corkish, J.D. (1977) Infectious bursal disease in Ghana. Bulletin de l Office International des Epizooties, 88, 293-298.
[18] Schobries, H.D., Wilke, I. and Schmidt, V. (1977) Infektiose Bursitis (Gumboro disease) in einem Broiler-best-and. Veterinary Medicine, 32, 700-704.
[19] Mcferran, J.B., McNulty, M.S., Mckillop, E.R., Conner, T.J., McCracken, R.M., Collins, D.S. and Allan G.M. (1980) Isolation and serological studies with infectious bursal disease viruses from fowl, turkey and duck: Demonstration of a second serotype. Avian Pathology, 9, 395-404. doi:10.1080/03079458008418423
[20] Tsukamoto, K., Tanimura, N., Kakita, S., Ota, K., Mase, M., Imai, K. and Hihara, H. (1995) Efficacy of three live vaccines against highly virulent infections bursal disease virus in chickens with or without maternal antibodies. Avian Disease, 39, 218-229. doi:10.2307/1591863
[21] Jackwood, D.J. and Saif, Y.M. (1983) Prevalence of antibodies to infectious bursal disease virus serotypes I and II in 75 Ohio Chicken. Avian Disease, 27, 850-854. doi:10.2307/1590331
[22] Etterradossi, N. (2001) Major advances in infectious bursal disease virus (IBV) research seen the first international IBDV/.CIAV symposium (Rauischholzhausen, Germany, 1994) Proceeding of II International symposium on infectious bursal disease and Chicken Infectious Anaemia, Rauischholzhausen, 16-20 July 2001, 6-23.
[23] Jackwood, D.J., Saif, Y.M. and Hughes, J.H. (1982) Characteristics and serological studies of two serotypes of infectious bursal disease virus in turkeys. Avian Disease, 26, 871-882. doi:10.2307/1589875
[24] Mcferran, J.B., McNulty, M.S., Mckillop, E.R., Conner, T.J., McCracken, R.M., Collins, D.S. and Allan, G.M. (1980) Isolation and serological studies with infectious bursal disease viruses from fowl, turkey and duck: Demonstration of a second serotype. Avian Pathology, 9, 395-404. doi:10.1080/03079458008418423
[25] Jackwood, D.J., Saif, Y.M. and Moorhead, P.D. (1985) Immunogenicity of infectious bursal disease virus serotypes I and II IN chickens. Avian Disease, 29, 1184-1194. doi:10.2307/1590472
[26] Ismail, N., Saif, Y.M. and Moorhead, P.D. (1988) Lack of pathogenicity of five serotype 2 infectious bursal disease viruses in chickens. Avian Disease, 32, 757-759. doi:10.2307/1590995
[27] Jackwood, D.J., Saif, Y.M. and Hughes, J.H. (1982) Characteristics and serological studies of two serotypes of infectious bursal disease virus in turkeys. Avian Disease, 26, 871-882. doi:10.2307/1589875
[28] Ismail, N.M., Saif, Y.M., Wigle, W.L., Havenstein G.B. and Jackson, C. (1990) Infectious bursal disease virus variant from commercial Leghorn pullets. Avian Disease, 34, 141-145.
[29] Jackwood, D.J., Saif, Y.M. and Moorhead, P.D. (1985) Immunogenicity of infectious bursal disease virus serotypes I and II IN chickens. Avian Disease, 29, 1184-1194. doi:10.2307/1590472
[30] Saif, Y.M. (1984) Infectious bursal disease virus types in Proceedings of 19th National Meeting of Poult Heaith Condemn, Ocean City, 105-107.
[31] Cynthia (2005) Infectious bursal disease (Gumbro disase), Merck veterinary mammal, Merck & Co., Inc., White House Station, 2248-2253.
[32] Shome, B.R., Shome, R., Snvastava, N. and Bandy, A.K. (1997) Infectious bursal disease in the Andamas: Isolation and identification of the virus. Indian Veterinary Journal, 74, 281-283.
[33] Cereno, T.N. (2008) Infectious Bursal Disease (IBD): Causative agent, diagnosis and prevention. http://www.canadianpoultryca./infectious_bursal_disease.htm
[34] Chettle, N.J.C., Stuart and Wyeth, P.J. (1989) Outbreak of virulent infectious bursal disease in East Anglia. Veterinary Record, 125, 271-272. doi:10.1136/vr.125.10.271
[35] Vanden Berg, T.P. and Meulemans, G. (1991) Acute infectious bursal disease in poultry: protection afforded by maternally derived antibodies and interference with live vaccination. Avian Pathology, 20, 409-421. doi:10.1080/03079459108418779
[36] Onunkwo, O. (1975) Problems of gumboro disease of chickens in Nigeria. Journal of Nigeria Poultry Science, 2, 95-101.
[37] Lukert, P.D. and Saif, Y.M. (2003) Infectious bursal disease. In Saif, Y.M., Glisson, J.R., Fadly, A.M., McDougald, L.R. and Swayne, D.E. (Eds.), Diseases of Poultry, 11th Edition, Iowa State University Press, Ames, 161-180.
[38] Ezeibe, M.C.O., Okoye, J.O.A., Ogunniran, T.M., Okoroafor, O.N., Ezeala, I.E. and Ngene, A.A. (2012) Modification of the passive heamagglutination test for detection of infectious bursal disease virus. Health, 4, 653-655. doi:10.4236/health.2012.49102
[39] Gujarati, D.N (2000) Basic econometrics. 4th Edition, McGrahill Publishers, New York.

  
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