A case of kidney metastasis in vulvar squamous cell carcinoma: A case report and review of literature

Anita Agrawal, Kimberly A. Wood, Christopher K. Giede, Rajni Chibbar

College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Department of Obstetrics and Gynecology, Royal University Hospital, Saskatoon, Canada.
Department of Obstetrics and Gynecology, University of Saskatchewan, Saskatoon, Canada;.
Department of Pathology, Royal University Hospital, Saskatoon, Canada.

DOI: 10.4236/crcm.2013.25082                

Abstract

Vulvar cancer is an uncommon tumor and represents 3%-5% of all female genital tract malignancies. Squamous cell carcinoma (SCC) is the most common carcinoma of the vulva. Distant metastasis of recurrent vulvar squamous cell carcinoma is rare and occurs late in the disease process. We report the first case of kidney metastasis from a vulvar squamous cell carcinoma in a 68-year-old Caucasian female. On initial presentation she was treated with radical vulvectomy, upper urethrectomy with bilateral inguinal and deep femoral lymph node dissection. She was staged as FIGO stage IVA and also received adjuvant chemo-radiation. She remained in remission for 24 months. Subsequently she was found to have a kidney tumor and underwent nephrectomy and was diagnosed with metastatic squamous cell carcinoma from the vulva to the kidney. In cases of recurrent vulvar carcinoma distant metastasis to the bones, breast, and brain is only rarely reported. Metastasis to kidneys from vulvar carcinoma is exceptionally rare with no reported cases in the literature. Renal metastasis should be considered in the differential diagnosis of kidney tumor in this group of women.

Keywords

Vulva; Squamous Cell Carcinoma; Kidney Metastasis

Conflicts of Interest

The authors declare no conflicts of interest.

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