Uterine Liposarcoma in a German Shephard Dog

Vullo Cecilia, Russo Marco, Mariotti Francesca, England C. W. Gary, Catone Giuseppe

.
School of Veterinary Medicine, Camerino University, Camerino, Italy.

DOI: 10.4236/ojvm.2013.32015                

Abstract

Uterine tumours in the bitch are considered rare. The most common are leiomyomas representing more than the 90% of all uterine canine tumours. Very few cases of uterine malignant tumours have been described in the veterinary literature and uterine liposarcoma had never discovered. Also in human medicine lipomatous tumours, whether benign or malignant, are very rare in the uterus. These tumours may arise from the misplacement of an embryonic progenitor cell, metaplasia of mature mesenchymal tissues of other types, perivascular adipocytes or from traumatic displacement of adipocytes. The authors describe a case of unilateral liposarcoma in the uterus of a German Shepherd dog and its radiographic, ultrasonographic evaluation and the histopathological appearance.

Keywords

Uterin Tumors; Liposarcoma; Immunohistochemistry; Dog

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	K. V. F. Jubb, P. C. Kennedy and N. C. Palmer, “Female Genital Tract,” Pathology of Domestic Animals, 5th Edition, Elsevier Saunders, 2007.
[2]	D. A. Fiorito, “Hyperestrogenism in Bitches,” Compendium on Continuing Education for the Practicing Veterinarian, Vol. 14, 1992, pp. 727-729.
[3]	W. B. Morrison, “Cancer of the Reproductive Tract,” Cancer in Dogs and Cats: Medical and Surgical Management, 2nd Edition, TNM Publishing, 2002.
[4]	S. D. Johnston, M. V. Root Kustritz and P. N. Olson, “Canine and Feline Theriogenology,” Saunders, Philadelphia, 2001.
[5]	M. D. McGavin and J. F. Zachary, “Female Reproductive System,” Pathologic Basis of Veterinary Disease, 4th Edition, Mosby Elsevie, 2007.
[6]	F. J. Pena, J. A. Gines, J. Duque, R. Martinez-Pe’re, L. Madejo, I. N. Martinez, J. M. Moran and S. Fernandez-Garcia, “Endometrial Adenocarcinoma and Mucometra in a 6 Years Old Alaska Malamute Dog,” Reproduction in Domestic Animals, Vol. 41, No. 2, 2006, pp. 189-190. doi:10.1111/j.1439-0531.2006.00645.x
[7]	K. Eker, M. R. Salmanoglu and S. A. Vural, “Unilateral Leiomyoma in the Mesosalpinx of a Dog,” Journal of the American Animal Hospital Association, Vol. 42, 2006, pp. 392-394.
[8]	D. J. Meuten, “Tumors of the Genital System. Tumors of the Skin and Soft Tissues,” Tumors in Domestic Animals, 4th Edition, Blackwell Publishing, 2002. doi:10.1002/9780470376928
[9]	W. B. Morrison, “Cancer of Reproductive Tract,” Cancer in Dogs and Cats, TNM Publishing, 2002.
[10]	C. E. Payne-Johnson, D. F. Kelly and P. T. Davies, “Endometrial Carcinoma in a Young Dog,” Journal of Comparative Pathology, Vol. 96, No. 4, 1986, pp. 463-467. doi:10.1016/0021-9975(86)90042-3
[11]	Y. Murakami, K. Uchida, R. Yamaguchi and S. Tateyama, “Diffuse Bilateral Hemangiosarcoma of the Uterus of a Dog,” Journal of Veterinary Medical Science, Vol. 63, 2001, pp. 191-193. doi:10.1292/jvms.63.191
[12]	T. A. Cave, R. Hine, F. Howie, H. Thompson and D. J. Arglye, “Uterine Carcinoma in a 10-Old-Month Golden Retriever,” Journal of Small Animal Practice, Vol. 43, No. 3, 2002, pp. 133-135. doi:10.1111/j.1748-5827.2002.tb00044.x
[13]	Y. K. Choi, J. Y. Lee, D. Y. Kim, J. I. Park, S. W. Jeong, H. M. Park and C. Park, “Uterine Extramedullary Plasmacytoma in a Dog,” Veterinary Record, Vol. 22, 2004, pp. 699-700. doi:10.1136/vr.154.22.699