Is There Any Indication for Prophylactic Brain Irradiation in the Management of Small Cell Prostate Cancer?

Joseph Kattan, Hampig Kourie, Pierre Sarkis, Joseph Gharios, Joelle Antoun

Saint Joseph Hospital, Raymond and Aida Najjar Medical Center, Saint Joseph University, Beirut, Lebanon.

DOI: 10.4236/jct.2013.44A001                

Abstract

Small cell prostate carcinoma (SCPC) is an extremely rare pathology with an aggressive behavior, characterized by early brain metastases. We describe three cases of SCPC where brain metastases occurred despite response to chemotherapy. The benefit of prophylactic brain irradiation (PBI), as part of the management of SCPC, is discussed and compared to its indications in small cell lung cancer.

Keywords

Small Cell Carcinoma; Prostate Cancer; Brain Metastases; Prophylactic Brain Irradiation

Conflicts of Interest

The authors declare no conflicts of interest.

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