Apparent Solubility of Natural Products Extracted with Near-Critical Carbon Dioxide

Helena Sovová

Institute of Chemical Process Fundamentals of the Academy of Sciences of the Czech Republic, Prague, Czech Republic.

DOI: 10.4236/ajac.2012.312A127                

Abstract

The apparent solubility controls the initial stage of supercritical fluid extraction of natural products, which is most important for the process economics. Based on the literature, data on CO₂ apparent solubility of volatile substances from different matrices as leaves, flowers, rhizomes and seeds were collected and compared with their thermodynamic solubility. The adsorption isotherm derived by del Valle and Urrego as a modification of the isotherm proposed by Perrut et al. is universal enough to interpret these data as well as the apparent solubility of vegetable oils from seeds, for which it was originally proposed. When the apparent solubility of minor extract components in CO₂ is compared with their thermodynamic solubility, their fraction in the extracted mixture should be taken into account.

Keywords

Supercritical Fluid Extraction; Solubility; Adsorption Isotherm; Vegetable Oils; Volatile Compounds

Conflicts of Interest

The authors declare no conflicts of interest.

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