[1]
|
J. W. Kim, A. S. Utada, A. F. Nieves, Z. B. Hu and D. A. Weitz, “Fabrication of Monodisperse Gel Shells and Func- tional Microgels in Microfluidic Devices,” Angewandte Chemie International Edition, Vol. 46, No. 11, 2007, pp. 1819-1822. doi:10.1002/anie.200604206
|
[2]
|
Y. Qiu and K. Park, “Environment-Sensitive Hydrogels for Drug Delivery,” Advanced Drug Delivery Reviews, Vol. 53, No. 3, 2001, pp. 321-339.
doi:10.1016/S0169-409X(01)00203-4
|
[3]
|
R. Langer and N. A. Peppas, “Advances in Biomaterials, Drug Delivery and Bionanotechnology,” AIChE Journal, Vol. 49, No. 12, 2003, pp. 2990-3006.
doi:10.1002/aic.690491202
|
[4]
|
S. Seiffert and D. A. Weitz, “Microfluidic Fabrication of Smart Microgels from Macromolecular Precusors,” Poly- mer, Vol. 51, No. 25, 2010, pp. 5883-5889.
doi:10.1016/j.polymer.2010.10.034
|
[5]
|
S. Abraham, E. H. Jeong, T. Arakawa, S. Shoji, K. C. Kim, I. Kim and J. S. Go, “Microfluidic Assisted Syn- thesis of Well-Defined Spherical Polymeric Microcap- sules and Their Utilization as Potential Encapsulants,” Lab Chip, Vol. 6, No. 6, 2006, pp. 752-756.
doi:10.1039/b518006f
|
[6]
|
G. F. Christopher and S. L. Anna, “Microfluidic Methods for Generating Continuous Droplets Stream,” Journal of Physics D: Applied PhysicsEmail alert RSS feed, Vol. 40, No. 19, 2007, pp. R319.
doi:10.1088/0022-3727/40/19/R01
|
[7]
|
J. D. Wan, “Microfluidic-Based Synthesis of Hydrogel Particles for Cell Microencapsulation and Cell-Based Drug Delivery,” Polymer, Vol. 4, No. 4, 2012, pp. 1084- 1108. doi.10.3390./polymer4021084
|
[8]
|
J. D. Wan, A. Bick, M. Sullivan, H. A. Stone, “Con- trollable Microfluidic Production of Microbubbles in Water-In-Oil Emulsion and the Formation of Porous Microparticles,” Advanced Materials, Vol. 20, No. 17, 2008, pp. 3314-3318. doi:10.1002/adma.200800628
|
[9]
|
M. Seo, Z. H. Nie, S. Q. Xu, M. Mok, P. C. Lewis, R. Graham and E. Kumacheva, “Continuous Microfluidic Reactors for Polymer Particles,” Langmuir, Vol. 21, No. 25, 2005, pp. 11614-11622. doi:10.1021/la050519e
|
[10]
|
D. Dendukuri and P. S. Doyle, “The Synthesis and Assem- bly of Polymeric Microparticles Using Microfluidics,” Advanced Materials, Vol. 21, No. 41, 2009, pp. 1-16.
doi:10.1002/adma.200803386
|
[11]
|
B. Kintses, L. D. Van Vliet, S. R. A. Devenish and F. Holfelder, “Microfluidic Droplets: New Integrated Work- flows for Biological Experiments,” Current Opinion in Chemical Biology, Vol. 14, No. 5, 2010, pp. 548-555.
doi:10.1016/j.cbpa.2010.08.013
|
[12]
|
A. B. Theberge, F. Courtois, Y. Schaerli, M. Fischlechner, C. Abell, F. Hollfelder and W. T. S. Huck, “Microdrop- lets in Microfluidics: an Evolving Platform for Discove- ries in Chemistry and Biology,” Angewandte Chemie International Edition, Vol. 49, No. 34, 2010, pp. 5846- 5868. doi:10.1002/anie.200906653
|
[13]
|
R. L. Srinivas, S. C. Chapin and P. S. Doyle, “Aptamer- Functionalized Microgel Particles for Protein Detection,” Analytical Chemistry, Vol. 83, No. 23, 2011, pp. 9138- 9145. doi:10.1021/ac202335u
|
[14]
|
C. Berkland, K. Kim, D. W. Pack, “Precision Polymer Microparticles for Controlled-Release Drug Delivery,” ACS Symposium Series, Vol. 879, Chapter 14, 2004, pp. 197-213.
|
[15]
|
B. Rotman, “Measurement of Activity of Single Mole- cules of β-D-Galactosidase,” Proceedings of the National Academy Science of USA, Vol. 47, No. 12, 1961, pp. 1981-1991. doi:10.1073/pnas.47.12.1981
|
[16]
|
J. K. Oh, R. Drumright, D. J. Siewart and K. Matyjas- zewski, “The Development of Microgels/Nanogels for Drug Delivery Application,” Progress in Polymer Science, Vol. 33, No. 4, 2008, pp. 448-477.
doi:10.1016/j.progpolymsci.2008.01.002
|
[17]
|
H. C. Shum, A. R. Abate, D. lee, A. R. Studart, B. G. Wang, C. H. Chen, J. L. Thiele, R. K. Shah, A. Krummel and D. A. Weitz, “Droplet Microfluidic for Fabrication of Non-Spherical Particles,” Macromolecular Rapid Commu- nications, Vol. 31, No. 2, 2010, pp. 108-118.
doi:10.1002/marc200900590
|
[18]
|
M. Marquis, D. Renard, and B. Cathala, “Microfluidic Generation and Selective Degradation of Biopoly-mer- Based Janus Microbeads,” Biomacromolecules, Vol. 13, No. 4, 2012, pp. 1197-1203. doi:10.1021/bm300159u
|
[19]
|
B. K. Lee, Y. H. Yun, J. S. Choi, Y. C. Choi, J. D. Kim and Y. W. Cho, “Fabrication of Drug-Loaded Polymer Mi- croparticles with Arbitrary Geometries Using a Piezo- electric Inject Printing System,” International Journal of Pharmaceutics, Vol. 427, No. 2, 2012, pp. 305-310.
doi:10.1016/j.ijpharm.2012.02.011
|
[20]
|
F. Ikkai, S. Iwamoto, E. Adachi and M. Nakajima, “New Method of Producing Mono-Sized Polymer Gel Particles Using Microchannel Emulsification and UV Irradiation,” Colloid and Polymer Science, Vol. 283, No. 10, 2005, pp. 1149-1153. doi:10.1007/s00396-005-1271-z
|
[21]
|
Z. Q. Chang, C. A. Serra, M. Bouquey, L. Prat and G. Hadziioannou, “Co-Axial Capillaries Microfluidic Device for Synthesizing Size- and Morphology-Controlled Poly- mer Core-Polymer Shell Particles,” Lab Chip, Vol. 9, No. 20, 2009, pp. 3007-3011. doi:10.1039/b913703c
|
[22]
|
M. Zourob, S. Mohr, A. G. Mayes, A. Macaskill, N. Perez- moral, P. R. Fielden and N. J. Goddard, “A Micro-Reac- tor for Preparing Uniform Molecularly Imprinted Polymer Beads,” Lab Chip, Vol. 6, No. 2, 2006, pp. 296-301.
doi:10.1039/b513195b
|
[23]
|
E. Brouzes, “Droplet Microfluidics for Single-Cell Analy- sis,” Methods in Molecular Biology, Vol. 853, No. 10, 2012, pp. 105-139. doi.10.1007/978-1-61779-567-1_10
|
[24]
|
H. Song, D. L. Chen, R. F. Ismagilov, “Reactions in Drop- lets in Microfluidic Channels,” Angewandte Chemie Inter- national Edition, Vol. 45, No. 44, 2006, pp. 7336-7365.
doi:10.1002/anie.200601554
|
[25]
|
K. S. Huang, T. H. Lai and Y. C. Lin, “Manipulating the Generation of Ca-Alginate Microspheres Using Micro- fluidic Channels as a Carrier of Gold Nanoparticles,” Lab Chip, Vol. 6, No. 7, 2006, pp. 954-957.
doi.10.1039/B606424H
|
[26]
|
P. Garstecki, M. J. Fuerstman, H. A. Stoen and G. M. Whiteside, “Formation of Droplets and Bubbles in a Micro- fluidic T-Junction-Scaling and Mechanism of Break-Up,” Lab Chip, Vol. 6, No. 3, 2006, pp. 437-446.
doi:10.1039/b510841a
|
[27]
|
C. N. Baroun, F. Gallaire and R. Dangla, “Dynamics of Microfluidic Droplets,” Lab Chip, Vol. 10, No. 16, 2010, pp. 2032-2045. doi:10.1039/c001191f
|
[28]
|
Z. H. Nie, M. S. Seo, S. Q. Xu, P. C. Lewis, M. Mok, E. Kumacheva, G. M. Whitesides, P. Garstecki and H. A. Stone, “Emulsification in a Microfluidic Flow-Focusing Device: Effect of the Viscosities of the Liquids,” Micro- fluid Nanofluid, Vol. 5, No. 5, 2008, pp. 585-594.
doi:10.1007/s10404-008-0271-y
|
[29]
|
M. Seo, I. Gorelikov, R. Williams and N. Matsuura, “In- fluence of Electrolyte Composition on the Photovoltaic Performance and Stability of Dye-Sensitized Solar Cells with Multiwalled Carbon Nanotube Catalysts,” Langmuir, Vol. 26, No. 12, 2010, pp. 13855-13860.
doi:10.1021/la100406p
|
[30]
|
L. S. Roach, H. Song, R. F. Ismagilov, “Controlling Non- Specific Protein Adsorption in a Plug-Based Microfluidic System by Controlling Interfacial Chemistry Using Fluo- rous-Phase Surfactants,” Analytical Chemistry, Vol. 77, No. 3, 2005, pp. 785-796. doi:10.1021/ac049061w
|
[31]
|
J. W. Choi, D. K. Kang, H. Park, A. J. deMello and S. I. Chang, “High-Throughput Analysis of Protein-Protein In- teractions in Picoliter-Volume Droplets Using Fluore- scence Polarization,” Analytical Chemistry, Vol. 84, No. 8, 2012, pp. 3849-3854.doi:10.1021/ac300414g
|
[32]
|
S. Y. Jung, S. T. Retterer and C. P. Collier, “Interfacial Tension Controlled Fusion of Individual Femolitre Drop- lets and Triggering of Confined Chemical Reactions on Demand,” Lab Chip, Vol. 10, No. 24, 2010, pp. 3373- 3376. doi.10.1039/C0LC00376J
|
[33]
|
M. Meier, J. Kennedy-Darling, S. H. Choi, E. M. Nor- strom, S. S. Sisodia and R. F. Ismagilov, “Plug-Based Micro- fluidics with Defined Surface Chemistry to Miniaturize and Control Aggregation of Amyloidogenic Peptides,” An- gewandte Chemie International Edition, Vol. 48, No. 8, 2009, pp. 1487-1489.
|
[34]
|
J. Clausell-Tormos, D. Lieber, J. C. Baret, A. Ei-Harrak, O. J. Miller, L. Frenz, J. Blouwolff, K. J. Humphry, S. Koster, H. Duan. C. Holtze, D. A. Weitz, A. D. Griffiths and C. A. Merten, “Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms,” Chemical Biology, Vol. 15, No. 7, 2008, pp. 427-437.
|
[35]
|
A. P. Aijian, D. Chatterjee and R. L. Garrell, “Fluorinated Liquid-Enabled Protein Handing and Surfactant-Aided Crystallization for Fully in Situ Digital Microfluidic MADI-MS Analysis,” Lab Chip, Vol. 12, No. 14, 2012, pp. 2552-2559. doi:10.1039/c2lc21135a
|
[36]
|
C. Holtze, A. C. Rowat, J. J. Agresti, J. B. Hutchison, F. E. Angile, C. H. J. Schmitz, S. Koster, H. Duan, K. J. Humphry, R. A. Scanga, J. S. Johnson, D. Pisignano and D. A. Weitz, “Biocompatible Surfactants for Water-In- Fluorocarbon Emulsions,” Lab Chip, Vol. 8, No. 10, 2008, pp. 1632-1639. doi:10.1039/b806706f
|
[37]
|
C. H. Chen, A. Sarkar, Y. A. Song, M. A. Miller, S. J. Kim, L. G. Griffith, D. A. Lauffenburger and J. Y. Han, “Enhancing Protease Activity Assay in Droplet-Based Mi- crofluidics Using a Biomolecule Concentrator,” Journal of American Chemical Society, Vol. 133, No. 27, 2011, pp. 10368-10371. doi:10.1021/ja2036628
|
[38]
|
J. C. Baret, “Surfactants in Droplet-Based Microfluidics,” Lab Chip, Vol. 12, No. 3, 2012, pp. 422-433.
doi:10.1039/c1lc20582j
|
[39]
|
D. Velasco, E. Tumarkin and E. Kumacheva, “Micro- fluidic Encapsulation of Cells in Polymer Microgels,” Small, Vol. 8, No. 11, 2012, pp. 1633-1642.
doi:10.1002/smll.201102464
|
[40]
|
E. Tumarkin and E. Kumacheva, “Microfluidic Genera- tion of Microgels from Synthetic and Natural Polymers,” Chemical Society Reviews, Vol. 38, No. 8, 2009, pp. 2161- 2168. doi:10.1039/b809915b
|
[41]
|
E. Kumacheva and P. Garstecki, “Microfluidic Reactors for Polymer Particles,” John Wiley & Sons, New York, 2011.
|
[42]
|
T. Thorsen, R. W. Roberts, F. H. Arnold and S. R. Quake, “Dynamic Pattern Formation in a Vesicle-Generating Mi- crofluidic Device,” Physical Review Letters, Vol. 86, No. 18, 2001, pp. 4163-4166.
doi:10.1103/PhysRevLett.86.4163
|
[43]
|
C. Priest, S. Herminghaus and R. Seemann, “Generation of Monodisperse Gel Emulsion in a Microfluidic Device,” Applied Physical Letters, Vol. 88, No. 2, 2006, 3 p.
doi:10.1063/1.2164393
|
[44]
|
A. R. Abate, A. Poitzsch, Y. Hwang, J. Lee, J. Czerwin- ska and D. A. Weitz, “Impact of Inlet Channel Geome- try on Microfluidic Drop Formation,” Physical Review E, Vol. 80, No. 2, 2009, 5 p.
doi:10.1103/PhysRevE.80.026310
|
[45]
|
I. Kobayashi, S. Mukataka and M. Nakajima, “Production of Monodisperse Oil-in-Water Emulsion Using a Large Silicon Straight-Through Microchannel Plate,” Industrial & Engineering Chemisrty Research, Vol. 44, No. 15, 2005, pp. 5852-5856. doi:10.1021/ie050013r
|
[46]
|
I. Kobayashi, K. Uemura and M. Nakajima, “Formulation of Monodisperse Emulsions Using Submicron-Channel Arrays,” Colloids and Surfaces A: Physicochemical and Engineering Aspects, Vol. 296, No. 1-3, 2007, pp. 285- 289. doi:10.1016/j.colsurfa.2006.09.015
|
[47]
|
I. Kobayashi, M. Nakajima, H. Nabetani, Y. J. Kikuchi, A. Shohno and K. Satoh, “Preparation of Micron-Scale Mono- disperse Oil-in-Water Microspheres by Microchannel Emul- sification,” Journal of the American Oil Chemists’ Society, Vol. 78, No. 8, 2001, pp. 797-802.
doi:10.1007/s11746-001-0345-5
|
[48]
|
M. T. Guo, A. Rotem, J. A. and D. A. Weitz, “Droplet Microfluidics for High-Throughput Biological Assays,” Lab Chip, Vol. 12, No. 12, 2012, pp. 2146-2155.
doi:10.1039/c2lc21147e
|
[49]
|
S. Y. Teh, R. Lin, L. H. Hung and A. P. Lee, “Droplet Microfluidics,” Lab Chip, Vol. 8, No. 2, 2008, pp. 198- 220. doi:10.1039/b715524g
|
[50]
|
H. N. Yow and A. F. Routh, “Formation of Liquid Core- Polymer Shell Microcapsules,” Soft Matter, Vol. 2, No. 11, 2006, pp. 940-949. doi:10.1039/b606965g
|
[51]
|
T. Kanai, D. Lee, H. C. Shum and D. A. Weitz, “Fabri- cation of Tunable Spherical Colloidal Crystals Immo- bilized in Soft Hydrogels,” Small, Vol. 6, No. 7, 2010, pp. 807-810. doi:10.1002/smll.200902314
|
[52]
|
S. Seiffert, J. Dubbert, W. Richtering, D. A. Weitz, “Re- duced UV Light Scattering in PDMS Microfluidic De- vices,” Lab Chip, Vol. 11, No. 5, 2011, pp. 966-968.
doi:10.1039/c0lc00594k
|
[53]
|
P. Panda, S. Ali, E. Lo, B. G. Chung, T. A. Hatton, A. Khademhosseini and P. S. Doyle, “Stop-Flow Lithogra- phy to Generate Cell-Laden Microgel Particles,” Lab Chip, Vol. 8, No. 7, 2008, pp. 1056-1061.
doi:10.1039/b804234a
|
[54]
|
Y. Deng, N. Zhang, L. Zhao, X. Yu, X. Ji, W. Liu, S. Guo, K. Liu and Z. A. Zhao, “Rapid Purification of Cell En- capsulated Hydrogel Beads from Oil Phase to Aqueous Phase in a Microfluidic Device,” Lab Chip, Vol. 11, No. 23, 2011, pp. 4117-4121. doi:10.1039/c1lc20494g
|
[55]
|
Y. Morimoto, R. Tanaka and S. J. Takeuchi, “Cons- truction of 3D, Layered Skin, Microsized Tissues by Us- ing Cell Beads for Cellular Function Analysis,” Advanced Healthcare Materials, 2012.
doi:10.1002/adhm.201200189
|
[56]
|
S. Dror, “Designing Cell-Compatible Hydrogels for Bio- medical Application,” Science, Vol. 336, No. 6085, 2012, pp. 1124-1128.
|
[57]
|
J. W. Nichol and A. Khademhosseini, “Modular Tissue Engineering: Engineering Biological Tissue from the Bottom up,” Soft Matter, Vol. 5, No. 7, 2009, pp. 1312- 1319. doi:10.1039/b814285h
|
[58]
|
B. G. Chung, K. H. Lee, A. Khademhosseini and S. H. Lee, “Microfluidic Fabrication of Microengineered Hydro- gels and Their Application in Tissue Engineering,” Lab Chip, Vol. 12, No. 1, 2012, pp. 45-59.
doi:10.1039/c1lc20859d
|
[59]
|
Y. M. Ren, B. Yu, H. L. Cong, Y. R. Ma, Z. Z. Ma and X. Yuan, “Preparation of Monodisperse PEG Microspheres by a T-Junction Microfluidic Chip,” Advanced Materials Research, Vol. 465, No. 12, 2012, pp. 178-181.
doi:10.4028/www.scientific.net/AMR.465.178
|
[60]
|
Z. H. Nie, W. Li, M. Seo, S. Q. Xu and E. Kumacheva, “Janus and Ternary Particles Generated by Microfluidic Synthesis: Design, Synthesis and Self-Assembly,” Journal of American Chemical Society, Vol. 128, No. 29, 2006, pp. 9408-9412. doi:10.1021/ja060882n
|
[61]
|
C. H. Choi, J. H. Jung, T. S. Hwang and C. S. Lee, “In Situ Microfluidic Synthesis of Monodisperse PEG Micro- spheres,” Macromolecular Research, Vol. 17, No. 3, 2009, pp. 163-167. doi:10.1007/BF03218673
|
[62]
|
G. De Geest, J. P. Urbanski, T. Thorsen, J. Demeester and S. C. De Smedt, “Synthesis of Monodisperse Biodegra- dable Microgels in Microfluidic Devices,” Langmuir, Vol. 21, No. 23, 2005, pp. 10275-10279.
doi:10.1021/la051527y
|
[63]
|
D. K. Hwang, D. Dendukuri and P. S. Doyle, “Microflui- dic-Based Synthesis of Non-Spherical Magnetic Hydrogel Microparticles,” Lab Chip, Vol. 8, No. 10, 2008, pp. 1640- 1647. doi:10.1039/b805176c
|
[64]
|
C. A. Serra and Z. Chang, “Microfluidic-Assisted Synthe- sis of Polymer Particles,” Chemical Engineering & Tech- nology, Vol. 31, No. 8, 2008, pp. 1099-1115.
doi:10.1002/ceat.200800219
|
[65]
|
K. W. Bong, S. C. Chapin and P. S. Doyle, “Magnetic Bar- coded Hydrogel Microparticles for Multiplexed Detec- tion,” Langmuir, Vol. 26, No. 11, 2010, pp. 8008-8014.
doi:10.1021/la904903g
|
[66]
|
C. H. Chen, A. R. Abate, D. Lee, E. M. Terentjev and D. A. Weitz, “Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure,” Advan- ced Materials, Vol. 21, No. 31, 2009, pp. 3201-3204.
doi:10.1002/adma.200900499
|
[67]
|
S. Seiffert, J. Thiele, A. R. Abate and D. A. Weitz, “Smart Microgels Capsules from Macromolecular Precursors,” Journal of American Chemical Society, Vol. 132, No. 18, 2010, pp. 6606-6609. doi:10.1021/ja102156h
|
[68]
|
K. J. Lee, J. Yoon and J. Lahann, “Recent Advances with Anisotropic Particles,” Current Opinion in Colloid & Inter- face Science, Vol. 16, No. 3, 2011, pp. 195-202.
doi:10.1016/j.cocis.2010.11.004
|
[69]
|
R. F. Shepherd, J. C. Conrad, S. K. Rhodes, D. R. Link, M. Marquez, D. A. Weitz and J. A. Lewis, “Microfluidic Assembly of Homogeneous and Janus Colloid-Filled Hy- drogel Granules,” Langmuir, Vol. 22, No. 21, 2006, pp. 8618-8622. doi:10.1021/la060759+
|
[70]
|
Q. Wang, D. Zhang, H. B. Xu, X. L. Yang, A. Q. Shen and Y. J. Yang, “Microfluidic One-Step Fabrication of Radiopaque Alginate Microgels with in Situ Synthesized Barium Sulfate Nanoparticles,” Lab Chip, Vol. 12, No. 22, 2012, pp. 4781-4786. doi:10.1039/c2lc40740j
|
[71]
|
S. Seiffert, M. B. Romanowsky and D. A. Weitz, “Janus Microgels Produced from Functional Precursor Poly- mers,” Langmuir, Vol. 26, No. 18, 2010, pp. 14842-14847.
doi:10.1021/la101868w
|
[72]
|
C. L. Lewis, Y. Lin, C. X. Yang, A. K. Manocchi, K. P. Yuet, P. S. Doyle and H. M. Yi, “Microfluidic Fabrication of Hydrogel Microparticles Containing Functionalized Viral Nanotemplates” Langmuir, Vol. 26, No. 16, 2010, pp. 13436-13441. doi:10.1021/la102446n
|
[73]
|
D. Dendukuri, D. C. Pregibon, J. Collins, T. A. Hatton and P. S. Doyle, “Continuous-Flow Lithography for High- Throughput Microparticle Synthesis,” Nature Materials, Vol. 5, No. 5, 2006, pp. 365-369. doi.10.1038/nmat1617
|
[74]
|
G. J. M. Fechine, J. A. G. Barros and L. H. Catalani, “Poly(N-Vinyl-2-Pyrrolidone) Hydrogel Production by Ul- traviolet Radiation: New Methodologies to Accelerate Crosslinking,” Vol. 45, No. 14, Polymer, pp. 4705-4709.
doi:10.1016/j.polymer.2004.05.006
|
[75]
|
S. A. Lee, S. E. Chung, W. Park, S. H. Lee and S. H. Kwon, “Three-Dimensional Fabrication of Heterogeneous Microstructures Using Soft Membrane Deformation and Opofluidic Maskless Lithography,” Lab Chip, Vol. 9, No. 12, 2009, pp. 1670-1675. doi:10.1039/b819999j
|
[76]
|
T. Rossow, J. A. Heyman, A. J. Ehrlicher, A. Langhoff, D. A. Weitz, R. Haag and S. Seiffert, “Controlled Synthesis of Cell-Laden Microgels by Radical-Free Gelation in Drop- let Microfluidics,” Journal of American Chemical Society, Vol. 134, No. 10, 2012, pp. 4983-4989.
doi:10.1021/ja300460p
|
[77]
|
R. K. Shah, J. W. Kim, J. J. Agresti, D. A. Weitz and L. Y. Chu, “Fabrication of Monodisperse Thermosensitive Microgels and Gel Capsules in Microfluidic Devices,” Soft Matter, Vol. 4, No. 12, 2008, pp. 2303-2309.
doi:10.1039/b808653m
|
[78]
|
L. Y. Chu, J. W. Kim, R. K. Shah and D. A. Weitz, “Mono- disperse Thermoresponsive Microgels with Tunable Vo- lume-Phase Transition Kinetics,” Advanced Functional Ma- terials, Vol. 17, No. 17, 2007, pp. 3499-3504.
doi:10.1002/adfm.200700379
|
[79]
|
W. J. Duncanson, T. Lin, A. R. Abate, S. Seiffert, R. K. Shah and D. A. Weitz, “Microfluidic Synthesis of Advan- ced Microparticles for Encapsulation and Controlled Re- lease,” Lab Chip, Vol. 12, No. 12, 2012, pp. 2135-2145.
doi:10.1039/c2lc21164e
|
[80]
|
N. Raz, J. K. Li, L. K. Fiddes, E. Tumarkin, G. C. Walker and E. Kumacheva, “Microgels with an Interpenetrating Network Structure as a Model System for Cell Studies,” Macromolecules, Vol. 43, No. 17, 2010, pp. 7277-7281.
doi:10.1021/ma101231z
|
[81]
|
P. Roca-Cusachs, I. Almendros, R. Sunyer, N. Gavara, R. Farre and D. Navajas, “Rheology of Passive and Adhe- sion-Activated Neutrophils Probed by Atomic Force Mi- croscopy,” Biophysical Journal, Vol. 91, No. 9, 2006, pp. 3508- 3518. doi:10.1529/biophysj.106.088831
|
[82]
|
E. P. Wojcikiewicz, X. H. Zhang, A. Chen and V. T. Moy, “Contributions of Molecular Binding Events and Cellular Compliance to the Modulation of Leukocyte Adhesion,” Journal of Cell Science, Vol. 116, No. 15, 2003, pp. 2531-2539. doi:10.1242/jcs.00465
|
[83]
|
K. Q. Jiang, C. Xue, C. Arya, C. R. Shao, E. O. George, D. L. DeVoe and S. R. Raghavan, “A New Approach to in Situ Micromanufacturing: Microfluidic Fabrication of Magnetic and Fluorescent Chains Using Chitosan Micro- particles as Building Blocks,” Small, Vol. 7, No. 17, 2011, pp. 2470-2476.
|
[84]
|
R. C. Luo, B. Neu and S. S. Venkatraman, “Surface Func- tionalization of Nanoparticles to Control Cell Interactions and Drug Release,” Small, Vol. 8, No. 16, 2012, pp. 2585- 2594. doi:10.1002/smll.201200398
|
[85]
|
R. A. A. Muzzarelli, “Genipin-Crosslinked Chitosan Hydro- gels as Biomedical and Pharmaceutical Aids,” Carbon- hydrate Polymers, Vol. 77, No. 1, 2009, pp. 1-9.
doi:10.1016/j.carbpol.2009.01.016
|
[86]
|
M. Rubinstein and R. H. Colby, “Polymer Physics,” Oxford University Press, Oxford, 2003.
|
[87]
|
S. Ladet, L. David and A. Domard, “Multi-Membrane Hydrogels,” Nature, Vol. 452, No. 6, 2008, pp. 76-80.
doi:10.1038/nature06619
|
[88]
|
S. Q. Xu, Z. H. Nie, M. Seo, P. Lewis, E. Kumacheva, H. A. Stone, P. Garstecki, D. B. Weibel, I. Gitlin and G. M. Whitesides, “Generation of Monodisperse Particles by Us- ing Microfluidics: Control over Size, Shape and Com- position,” Angewandte Chemie International Edition, Vol. 44, No. 5, 2005, pp. 724-728.
doi:10.1002/anie.200462226
|
[89]
|
S. Iwamoto, K. Nakagawa, S. Sugiura and M. Nakajima, “Preparation of Gelatin Microbeads with a Narrow Size Distribution Using Microchannel Emulsification,” AAPS PharmSciTech, Vol. 3, No. 3, 2002, pp. 72-76.
doi:10.1007/BF02830623
|
[90]
|
B. Walther, C. Cramer, A. Tiemeyer, L. Hamberg, P. Fis- cher, E. J. Windhab and A. M. Hermansson, “Drop De- formation Dynamics and Gel Kinetics in a Co-Flowing Water-in-Oil System,” Journal of Colloid and Interface Science, Vol. 286, No. 1, 2005, pp. 378-386.
doi:10.1016/j.jcis.2005.01.054
|
[91]
|
G. A. Di Lullo, S. M Sweeney, J. Korkko, L. Ala-Kokko and J. D. San Antonio, “Mapping the Ligand-Binding Sites and Disease-Associated Mutations on the Most Abundant Protein in the Human, Type I Collagen,” Journal of Bio- logical Chemistry, Vol. 277, No. 8, 2002, pp. 4223-4230.
doi:10.1074/jbc.M110709200
|
[92]
|
Y. Morimoto, W. H. Tan and S. Takeuchi, Biomed. “Three- Dimensional Axisymmetric Flow-Focusing Device Using Stereolithography,” Microdevices, Vol. 11, No. 2, 2009, pp. 369-377. doi:10.1007/s10544-008-9243-y
|
[93]
|
S. M. Hong, H. J. Hsu, R. Kaunas and J. Kameoka, “Col- lagen Microsphere Production on a Chip,” Lab Chip, Vol. 12, No. 18, 2012, pp. 3277-3280. doi:10.1039/c2lc40558j
|
[94]
|
S. Sugiura, T. Oda, Y. Izumida, Y. Aoyagi, M. Satake, A. Ochiai, N. Ohkohchi and M. Nakajima, “Size Control of Calcium Alginate Beads Containing Living Cells Using Micro-Nozzle Array,” Biomaterials, Vol. 26, No. 16, 2005, pp. 3327-3331.
doi:10.1016/j.biomaterials.2004.08.029
|
[95]
|
W. H. Tan, and S. Takeuchi, “Monodisperse Alginate Hy- drogel Microbeads for Cell Encapsulation,” Advanced Ma- terials, Vol. 19, No. 18, 2007, pp. 2696-2701.
doi:10.1002/adma.200700433
|
[96]
|
H. Zhang, E. Tumarkin, R. Peerani, Z. Nie, M. A. Sullan, G. C. Walker and E. Kumacheva, “Microfluidic Produc- tion of Biopolymer Microcapsules with Controlled Mor- phology,” Journal of American Chemical Society, Vol. 128, No. 37, 2006, pp. 12205-12210.
doi:10.1021/ja0635682
|
[97]
|
P. S. Dittrich and A. Manz, “Lab-on-a-Chip: Microflui- dics in Drug Discovery,” Nature Reviews Drug Discovery, Vol. 5, No. 5, 2006, pp. 210-218. doi:10.1038/nrd1985
|
[98]
|
C. H. Yang, K. S. Huang and J. Y. Chang, “Manufac- turing Monodisperse Chitosan Microparticles Containing Ampicillin Using a Microchannel Chip,” Biomedical Micro- devices, Vol. 9, No. 2, 2007, pp. 253-259.
doi:10.1007/s10544-006-9029-z
|
[99]
|
C. H. Yang, K. S. Huang, Y. S. Lin, K. Lu, C. C. Tzeng, E. C. Wang, C. H. Lin, W. Y. Hsu and J. Y. Chang, “Micro- fluidic Assisted Synthesis of Multi-Functional Polycapro- lactone Microcapsules: Incorporation of CsTe Quantum Dots, Fe3O4 Superparamagnetic Nanoparticles and Tamo- xifen Anticancer Drugs,” Lab Chip, Vol. 9, No. 7, 2009, pp. 961-965. doi:10.1039/b814952f
|
[100]
|
L. Y. Chu, A. S. Utada, R. K. Shah, J. W. Kim and D. A. Weitz, “Controllable Monodisperse Multiple Emulsion,” Angewandte Chemie International Edition, Vol. 46, No. 47, 2007, pp. 8907-8974. doi:10.1002/anie.200702736
|
[101]
|
G. Karoubi, M. L. Ormiston, D. J. Stewart and D. W. Cour- tman, “Single-Cell Hydrogel Encapsulation for Enhanced Survival of Human Marrow Stromal Cells,” Biomaterials, Vol. 30, No. 29, 2009, pp. 5445-5455.
doi:10.1016/j.biomaterials.2009.06.035
|
[102]
|
J. F. Edd, D. Di Carlo, K. J. Humphry, S. Koster, D. Irimia, D. A. Weitz and M. Toner, “Controlled Encapsu- lation of Single-Cells into Monodisperse Picolitre Drops,” Lab Chip, Vol. 8, No. 8, 2008, pp. 1262-1264.
doi:10.1039/b805456h
|
[103]
|
E. Tumarkin, L. Tzadu, E. Csaszar, M. Seo, H. Zhang, A. Lee, R. Peerani, K. Purpura, P. W. Zandstra and E. Kuma- cheva, “High-Throughput Combinatorial Cell Co-Culture Using Microfluidics,” Integrative Biology, Vol. 3, No. 6, 2011, pp. 653-662. doi:10.1039/c1ib00002k
|
[104]
|
B. M. Leung and M. V. Sefton, “A Modular Approach to Cardiac Tissue Engineering,” Tissue Engineering Part A, 2010, Vol. 16, No. 10, pp. 3207-3218.
doi:10.1089/ten.tea.2009.0746
|
[105]
|
D. A. Bruzewicz, A. P. McGuigan and G. M. Whitesides, “Fabrication of a Modular Tissue Construct in a Micro- fluidic Chip,” Lab Chip, Vol. 8, No. 5, 2008, pp. 663-671.
doi:10.1039/b719806j
|
[106]
|
C. C. Wang, K. C. Yang, K. H. Lin, H. C. Liu and F. H. Lin, “A Highly Organized Three-Dimensional Alginate Scaffold for Cartilage Tissue Engineering Prepared by Microfluidic Technology,” Biomaterials, Vol. 32, No. 29, 2011, pp. 7118-7126.
doi:10.1016/j.biomaterials.2011.06.018
|
[107]
|
J. Lee, M. J. Cuddihy, G. M. Cater and N. A. Kotov, “Engineering Liver Tissue Spheroids with Inverted Col- loidal Crystal Scaffolds,” Biomaterials, Vol. 30, No. 27, 2009, pp. 4687-4694.
http://dx.doi:10.1016/j.biomaterials.2009.05.024
|
[108]
|
C. S. Liu, J. J. Liu, D. Gao M. Y. Ding and J. M. Lin, “Fabrication of Microwell Arrays Based on Two-Dimen- tional Ordered Polystyrene Microspheres for High-Through- put Single-Cell Analysis,” Analytical Chemistry, Vol. 82, No. 22, 2010, pp. 9418-9424. doi:10.1021/ac102094r
|
[109]
|
C. Y. Li, D. K. Wood, C. M. Hsu and S. N. Bhatia, “DNA- Templated Assembly of Droplet-Derived PEG Micro- tissues,” Lab Chip, Vol. 11, No. 17, 2011, pp. 2967-2975.
doi:10.1039/c1lc20318e
|
[110]
|
Y. T. Matsunaga, Y. Morimoto and S. J. Takeuchi, “Mold- ing Cell Beads for Rapid Construction of Macroscopic 3D Tissue Architecture,” Advanced Healthcare Materials, Vol. 23, No. 3, 2011, pp. H90-H94.
|
[111]
|
N. K. Bawolin, M. G. Li, X. B. Chen and W. J. Zhang, “Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds,” Journal of Biomechanical Engineering, Vol. 132, No. 11, 2010, pp. 111001-111008.
doi:10.1115/1.4002551
|