Influence of obstetric factors on the development of postpartum antithyroid antibodies

José Morales Roselló, Beatriz Tirado Pelaez, Nuria Peralta Llorens

Clínica Morales, Valencia, Spain.

DOI: 10.4236/ojog.2012.21008                

Abstract

Aim: To correlate obstetric data with the appearance of antithyroid antibodies. Methods: A 6 months follow up was performed on 135 healthy women with assessment of TSH, T3, T4 and antithyroid antibodies (anti thyroglobulin and anti peroxidase). Correlation of diverse obstetrical parameters with the appearance of antithyroid antibodies at 2 and 6 months postpartum was determined. Results: Only two parameters were significant during the complete follow up: the newborn weight, which correlated with both antibodies (anti-thyroglobulin and anti-peroxidase) positivity and the maternal height, which exclusively correlated with anti-thyroglobulin positivity. Conclusions: Correlation of maternal height and newborn weight with positive autoantibodies allows to consider a future clinical screening test for this disorder.

Keywords

Antithyroid Antibodies; Maternal Screening; Microchimerism; Postpartum Thyroiditis

Conflicts of Interest

The authors declare no conflicts of interest.

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