A Multi-Center International Survey Related to the Nutritional Support after Hematopoietic Stem Cell Transplantation Endorsed by the ASIA Pacific Blood and Marrow Transplantation (APBMT)

Shigeo Fuji^1#, Takehiko Mori², Vincent Lee³, Jessica Cheng⁴, Natalie Linton⁴, Albert Lie⁵, Navin Khattry⁶, Akio Shigematsu⁷, Naoyuki Uchida⁸, Tetsuya Eto⁹, Nguyen Duy Thang¹⁰, Yi-Chang Liu¹¹, Deok-Hwan Yang¹², Jin Seok Kim¹³, Joon Ho Moon¹⁴, Dae-Young Kim¹⁵, Minako Iida¹⁶, Ritsuro Suzuki¹⁶, Yoshihisa Kodera¹⁷, Sung-Won Kim¹⁸

¹Department of Hematology, University Hospital Wuerzburg, Wuerzburg, Germany.
²Division of Hematology, Keio University Hos- pital, Tokyo, Japan.
³Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (China).
⁴Department of Nutrion Services, St Vincent’s Hospital Sydney, Sydney, Australia.
⁵Department of Medicine, Queen Mary Hospital, Hong Kong (China).
⁶Department of Medical Oncology, Tata Memorial Center, Mumbai, India.
⁷Department of Hematology and Oncology, Hokkaido University Hospital, Hokkaido, Japan.
⁸Department of Hematology, Toranomon Hospital, Tokyo, Japan.
⁹Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
¹⁰Hue Regional Hematology and Blood Transfusion Center, Hue Central Hospital, Hue City, Vietnam.
¹¹Department of Hematology and Oncology, Kaohsiung Medical University Hospital, Taiwan (China).
¹²Department of Hematology and Oncology, Chonnam National University Hwasun Hospital, Jeollanam-do, Korea.
¹³Division of Hematology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea (South).
¹⁴Department of Hematology and Oncology, Kyungpook National University Hospital, Daegu, Korea (South).
¹⁵Department of Hematology, Asan Medical Center, Seoul, Korea (South).
¹⁶Department of HSCT Data Management and Biostatistics, School of Medicine, Nagoya University, Nagoya, Japan.
¹⁷Department of Promotion for Blood and Marrow Transplantation, School of Medicine, Aichi Medical University, Nagakute, Japan.
¹⁸Department of Hematology and Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.

DOI: 10.4236/fns.2012.33060                

Abstract

Background: The nutritional support after hematopoietic stem cell transplantation (HSCT) has not been well established due to the scarcity of clinical trials. To conduct international clinical trials in Asia, we performed the questionnaire survey to investigate the current standard of nutritional support after HSCT. Method: We sent the questionnaire to the physicians nominated by the Asia Pacific Blood and Marrow Transplantation (APBMT) members of each country/ region. Result: We received 15 responses from 7 different countries/regions. The target calorie amount is 1.0 - 1.3 × basal energy expenditure (BEE) in 11 institutes when partial parenteral nutrition is used. When total parenteral nutrition (TPN) is used, the target calorie amount is 1.0 - 1.3 × BEE in 9 institutes and 1.3 - 1.5 × BEE in 4 institutes. Lipid emulsion is routinely used in 12 institutes. Multivitamins and trace elements are routinely added to TPN used in most institutes. It is still uncommon to use the immunonutrition. Blood glucose levels are routinely monitored in all institutes, but the target range varies (<110 in 2 institutes, <150 in 4 institutes, and <200 in 8 institutes). Conclusions: Basic nutritional support is similar in participating institutes. However, the target glucose level varies and the use of immunonutrition is rather rare. These points can be the theme of future clinical trials.

Keywords

Stem Cell Transplantation; Nutritional Support; Asia Pacific Blood and Marrow Transplantation

Conflicts of Interest

The authors declare no conflicts of interest.

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