Oral spindle cell lipomas

Abstract

Spindle cell lipoma is an histological type of lipoma which are rarely found in the oral cavity. We describe two cases of intraoral spindle cell lipomas. The pa- tients were men and presented painless slow growing masses in the left cheek and hard palate, measuring 50 × 30 mm and 23 × 20 mm respectively. Microsco- pically, both lesions presented a solid proliferation of mature fat cells intermixed with bundles of connec- tive tissue. Cells were immunopositive for S100 pro- tein and CD34 (one case), with low mitotic activity (Ki-67). The final diagnosis was spindle cell lipomas. The lesions were excised and no recurrence was no- ticed after six months. Oral spindle cell lipomas are unexpected to occur in the oral mucosa, and the main differential diagnosis is well-differentiated liposar- coma/atypical lipoma. Lesions are treated with sur-gical excision and recurrences are rare.

Share and Cite:

Caldeira, P. , Bernardes, V. , Miranda, A. , Telles, D. , Batista, R. , Ribeiro, C. and Silva, T. (2011) Oral spindle cell lipomas. Open Journal of Stomatology, 1, 202-206. doi: 10.4236/ojst.2011.14031.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Said-Al-Naief, N., Zahurullah, F.R. and Sciubba, J.J. (2001) Oral spindle cell lipoma. Annals of Diagnostic Pathology, 5, 207-215. doi:10.1053/adpa.2001.26973
[2] Vecchio, G., Amico, P., Caltabiano, R., Colella, G., Lanzafame, S. and Magro, G. (2009) Spindle cell/pleomor- phic lipoma of the oral cavity. Journal of Craniofacial Surgery, 20, 1992-1994. doi:10.1097/SCS.0b013e3181bd2dad
[3] Barnes, L., Eveson, J., Reichart, P., Sidransky, D., Eds. (2002) Pathology and genetics of tumours of soft tissue and bone. World Health Organization Classification of Tumours, IARC Press, Lyon, 427.
[4] Atik, E., Usta, U. and Aydin, N.E. (2002) Pleomorphic lipoma of the tongue. Otolaryngol Head Neck Surg, 126, 430-431. doi:10.1067/mhn.2002.123919
[5] Billings, S.D., Henley, J.D., Summerlin, D.J., Vakili, S. and Tomich, C.E. (2006) Spindle cell lipoma of the oral cavity. American Journal of Dermatopathology, 28, 28- 31. doi:10.1097/01.dad.0000189615.13641.4b
[6] Coimbra, F., Lopes, J.M., Figueiral, H. and Scully, C. (2006) Spindle cell lipoma of the floor of the mouth. A case report. Medicina Oral Patologia Oral y Cirugia Bucal, 11, E401-E403.
[7] Darling, M., Thompson, I. and Schneider, J. (2002) Spindle cell lipoma of the alveolar mucosa: a case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics, 93, 171-173. doi:10.1067/moe.2002.120520
[8] Imai, T., Michizawa, M., Shimizu, H., Imai, T., Yamamoto, N. and Yura, Y. (2008) Bilateral multiple spindle cell lipomas of the tongue. Oral Medicine, Oral Pathology, Oral Radiology & Endodontics, 106, 264-269.
[9] Piattelli, A., Perrotti, V., Fioroni, M. and Rubini, C. (2005) Spindle cell lipoma of the floor of the mouth: Report of a case. Auris Nasus Larynx, 32, 205-207. doi:10.1016/j.anl.2005.01.013
[10] Chikui, T., Yonetsu, K., Yoshiura, K., Miwa, K., Kanda, S., Ozeki, S. and Shinohara, M. (1997) Imaging findings of lipomas in the orofacial region with CT, US, and MRI. Oral Medicine, Oral Pathology, Oral Radiology & Endodontics, 84, 88-95.
[11] Bandéca, M.C., De Pádua, J.M., Nadalin, M.R., Ozório, J.E., Silva-Sousa, Y.T. and Da Cruz, P.D.E. (2007) Oral soft tissue lipomas: A case series. Journal of the Canadian Dental Association, 73, 431-434.
[12] Cappabianca, S., Colella, G., Pezzullo, M.G., Russo, A., Iaselli, F., Brunese, L. and Rotondo, A. (2008) Lipomatous lesions of the head and neck region: Imaging findings in comparison with histological type. Radiology Medicine, 113, 758-770. doi:10.1007/s11547-008-0258-5
[13] Nascimento, A.F., McMenamin, M.E. and Fletcher, C.D. (2002) Liposarcomas/atypical lipomatous tumors of the oral cavity: A clinicopathologic study of 23 cases. Annals of Diagnostic Pathology, 6, 83-93. doi:10.1053/adpa.2002.32375

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.