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Avocado and Cardiovascular Health

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DOI: 10.4236/ojemd.2015.57010    3,330 Downloads   4,149 Views   Citations

ABSTRACT

Avocado is a fruit which had a caloric density of 1.7 kcal per gram and a half unit (~70 g) is composed by 114 kcal, 4.6 g of fibers, 345 mg of potassium, 19.5 mg of magnesium, 1.3 mg of vitamin E and 57 mg of phytosterols. Approximately 75% of fiber’s avocado contents are considered insoluble and 25% are soluble. The avocado contains lipids that consist of 71% from monounsaturated fatty acids (MUFA), 13% from polyunsaturated (PUFA) and 16% from saturated fatty acids (SFA). Recent researches have shown that avocado may improve hypercholesterolemia and may be useful in the treatment of hypertension and type 2 diabetes mellitus (T2DM). This way, avocado plays an important role in the cardiovascular health. This review summarizes the potential benefits of avocado consumption in the prevention of cardiovascular risk factors and metabolic diseases.

Cite this paper

Weschenfelder, C. , dos Santos, J. , de Souza, P. , de Campos, V. and Marcadenti, A. (2015) Avocado and Cardiovascular Health. Open Journal of Endocrine and Metabolic Diseases, 5, 77-83. doi: 10.4236/ojemd.2015.57010.

References

[1] Montenegro, H.W.S. (1951) The Culture of Avocado. Melhoramentos, S?o Paulo, 11:102.
[2] Maranca, G. (1980) Commercial Fruit Growing: Mango and Avocado. Nobel, S?o Paulo, 81-133.
[3] Koller, O.C. (1992) Abacaticultura. UFRGS, Porto Alegre, 138.
[4] Canto, W.L., Santos L.C. and Travaglini, M.M.E. (1978) Avocado: The Crop to Processing and Marketing. Série frutas tropicais-1. ITAL, Campinas, 212.
[5] Dreher, M.L. and Davenport, A.J. (2013) Hass Avocado Composition and Potential Health Effects. Critical Reviews in Food Science and Nutrition, 53, 738-750. http://dx.doi.org/10.1080/10408398.2011.556759
[6] Naveh, E., Werman, M.J., Sabo, E. and Neeman, I. (2002) Defatted Avocado Pulp Reduces Body Weight and Total Hepatic Fat But Increases Plasma Cholesterol in Male Rats Fed Diets with Cholesterol. The Journal of Nutrition, 132, 2015-2018.
[7] USDA (U.S. Department of Agriculture) (2011) Avocado, Almond, Pistachio and Walnut Composition. Nutrient Data Laboratory. USDA National Nutrient Database for Standard Reference, Release 24. U.S. Department of Agriculture. Washington, DC.
[8] Unlu, N., Bohn, T., Clinton, S.K. and Schwartz, S.J. (2005) Carotenoid Absorption from Salad and Salsa by Humans Is Enhanced by the Addition of Avocado or Avocado Oil. The Journal of Nutrition, 135, 431-436.
[9] Wang, L., Bordi, P.L., Fleming, J.A., Hill, A.M. and Kris-Etherton, P.M. (2015) Effect of a Moderate Fat Diet with and without Avocados on Lipoprotein Particle Number, Size and Subclasses in Overweight and Obese Adults: A Randomized, Controlled Trial. Journal of the American Heart Association, 4, e001355. http://dx.doi.org/10.1161/jaha.114.001355
[10] Fulgoni 3rd, V.L., Dreher, M. and Davenport, A.J. (2013) Avocado Consumption Is Associated with Better Diet Quality and Nutrient Intake, and Lower Metabolic Syndrome Risk in US Adults: Results from the National Health and Nutrition Examination Survey (NHANES) 2001-2008. The Journal of Nutrition, 12, 1. http://dx.doi.org/10.1186/1475-2891-12-1
[11] Nicholson, G. and Hall, G.M. (2011) Diabetes Mellitus: New Drugs for a New Epidemic. British Journal of Anaesthesia, 107, 65-73. http://dx.doi.org/10.1093/bja/aer120
[12] Tangvarasittichai, S. (2015) Oxidative Stress, Insulin Resistance, Dyslipidemia and Type 2 Diabetes Mellitus. World Journal of Diabetes, 6, 456-480. http://dx.doi.org/10.4239/wjd.v6.i3.456
[13] American Diabetes Association (2014) Standards of Medical Care in Diabetes. Diabetes Care, 37, 14-80.
[14] Alhassan, A.J., Sule, M.S., Atiku, M.K., Wudil, A.M., Abubakar, H. and Mohammed, S.A. (2012) Effects of Aqueous Avocado Pear (Persea americana) Seed Extract on Alloxan Induced Diabetes Rats. Greener Journal of Medical Sciences, 2, 5-11.
[15] N’guessan, K., Amoikon, K.E. and Soro, D. (2009) Effect of Aqueous Extract of Persea americana Seeds on the Glycemia of Diabetic Rabbits. European Journal of Scientific Research, 26, 376-385.
[16] Ezejiofor, A.N., Okorie, A. and Orisakwe, O.E. (2013) Hypoglycaemic and Tissue-Protective Effects of the Aqueous Extract of Persea americana Seeds on Alloxan-Induced Albino Rats. The Malaysian Journal of Medical Sciences, 20, 31-39.
[17] Oboh, G., Isaac, A.T., Akinyemi, A.J. and Ajani, R.A. (2014) Inhibition of Key Enzymes Linked to Type 2 Diabetes and Sodium Nitroprusside Induced Lipid Peroxidation in Rats’ Pancreas by Phenolic Extracts of Avocado Pear Leaves and Fruit. International Journal of Biomedical Sciences, 10, 208-216.
[18] Rao, U.S. and Adinew, B. (2011) Remnant B-Cell-Stimulative and Anti-Oxidative Effects of Persea americana Fruit Extract Studied in Rats Introduced into Streptozotocin-Induced Hyperglycaemic State. African Journal of Traditional, Complementary and Alternative Medicines, 8, 210-217.
http://dx.doi.org/10.4314/ajtcam.v8i3.65277
[19] Ros, E. (2003) Dietary Cis-Monounsaturated Fatty Acids and Metabolic Control in Type 2 Diabetes. The American Journal of Clinical Nutrition, 78, 617-625.
[20] Wien, M., Haddad, E., Oda, K. and Sabaté, J. (2013) A Randomized 3 × 3 Crossover Study to Evaluate the Effect of Hass Avocado Intake on Post-Ingestive Satiety, Glucose and Insulin Levels, and Subsequent Energy Intake in Overweight Adults. Nutrition Journal, 12,155.
http://dx.doi.org/10.1186/1475-2891-12-155
[21] Colquhoun, D.M., Moores, D., Somerset, S.M. and Humphries, J.A. (1992) Comparison of the Effects on Lipoproteins and Apolipoproteins of a Diet High in Monounsaturated Fatty Acids, Enriched with Avocado, and a High-Carbohydrate Diet. The American Journal of Clinical Nutrition, 56, 671-677.
[22] Pahua-Ramos, M.E., Gardu?o-Siciliano, L., Dorantes-Alvarez, L., Chamorro-Cevallos, G., Herrera-Martínez, J., Osorio-Esquivel, O., et al. (2014) Reduced-Calorie Avocado Paste Attenuates Metabolic Factors associated with a Hypercholesterolemic-High Fructose Diet in Rats. Plant Foods for Human Nutrition, 69, 18-24. http://dx.doi.org/10.1007/s11130-013-0395-4
[23] Mendis, S., Puska, P. and Norrving, B. (2011) Global Atlas on Cardiovascular Disease Prevention and Control. World Health Organization.
[24] World Health Organization (2009) Global Health Risks: Mortality and Burden of Disease Attributable to Selected Major Risks. World Health Organization.
[25] Eckel, R.H., Jakicic, J.M., Ard, J.D., de Jesus, J.M., Houston, M.N., Hubbard, V.S., et al. (2013) AHA/ACC Guideline on Life Style Management to Reduce Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation, 129, S76-S99. http://dx.doi.org/10.1161/01.cir.0000437740.48606.d1
[26] Xavier, H.T., Izar, M.C., Faria Neto, J.R., Assad, M.H., Rocha, V.Z., Sposito, A.C., et al. (2013) V Brazilian Guideline of Dyslipidemia and Prevention of Atherosclerosis. Arquivos Brasileiros de Cardiologia, 101, 1-20. http://dx.doi.org/10.5935/abc.2013S010
[27] Santos, R.D., Gagliardi, A.C.M., Xavier, H.T., Magnoni, C.D., Cassani, R. and Lottenberg, A.M. (2013) Guidelines on the Consumption of Fats and Cardiovascular Health. Arquivos Brasileiros de Cardiologia, 100, 1-40.
[28] Sposito, A.C., Caramelli, B., Fonseca, F.A.H., Bertolami, M.C., Afiune Neto, A., Souza, A.D., et al. (2007) IV Brazilian Guideline of Dyslipidemia and Prevention of Atherosclerosis: Department of Atherosclerosis of the Brazilian Society of Cardiology. Arquivos Brasileiros de Cardiologia, 88, 2-19.
http://dx.doi.org/10.1590/S0066-782X2007000700002
[29] Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M.I., Corella, D., Arós, F., et al. (2013) Primary Prevention of Cardiovascular Disease with Mediterranean Diet. The New England Journal of Medicine, 368, 1279-1290. http://dx.doi.org/10.1056/NEJMoa1200303
[30] Salgado, J.M., Bin, C., Mansi, D.N. and Souza, A. (2008) Effects of Avocado (Persea americana Mill) Variety Hass in Blood Lipids of Hypercholesterolemic Rats. Ciência e Tecnologia dos Alimentos, 28, 922-928. http://dx.doi.org/10.1590/S0101-20612008000400025
[31] Grant, W.C. (1960) Influence of Avocados on Serum Cholesterol. Proceedings of the Society for Experimental Biology and Medicine, 104, 45-47. http://dx.doi.org/10.3181/00379727-104-25722
[32] Carranza, J., Alvizouri, M., Alvarado, M.R., Chávez, F., Gómez, M. and Herrera, J.E. (1995) Effects of Avocado on the Level of Blood Lipids in Patients with Phenotype II and IV Dyslipidemias. Archivos del Instituto de Cardiología de México, 65, 342-348.
[33] Pérez Méndez, O. and García Hernández, L. (2007) High-Density Lipoproteins (HDL) Size and Composition Are Modified in the Rat by a Diet Supplemented with “Hass” Avocado (Persea americana Miller). Archivos del Instituto de Cardiología de México, 77, 17-24.
[34] Boshtam, M., Razavi, A.E., Pourfarzam, M., Ani, M., Naderi, G.A., Basati, G., et al. (2013) Serum Paraoxonase Activity Is Associated with Fatty Acid Composition of High Density Lipoprotein. Diseases Markers, 35, 273-280. http://dx.doi.org/10.1155/2013/612035
[35] Wang, L., Bordi, P.L., Fleming, J.A., Hill, A.M. and Kris-Etherton, P.M. (2015) Effect of a Moderate Fat Diet with and without Avocados on Lipoprotein Particle Number, Size and Subclasses in Overweight and Obese Adults: Randomized, Controlled Trial. Journal of the American Heart Association, 4, e001355. http://dx.doi.org/10.1161/jaha.114.001355
[36] Bastien, M., Poirier, P., Leimeux, I. and Després, J.P. (2014) Overview of Epidemiology and Contribution of Obesity to Cardiovascular Disease. Progress in Cardiovascular Disease, 56, 369-381.
http://dx.doi.org/10.1016/j.pcad.2013.10.016
[37] Schwingshackl, L. and Hoffmann, G. (2012) Monounsaturated Fatty Acids and Risk of Cardiovascular Disease: Synopsis of the Evidence Available from Systematic Reviews and Meta-Analyses. Nutrients, 4, 1989-2007. http://dx.doi.org/10.3390/nu4121989
[38] Pieterse, E., Jerling, J.C., Oosthuizen, W., Kruger, H.S., Hanekom, S.M., Smuts, C.M., et al. (2005) Substitution of High Monounsaturated Fatty Acid Avocado for Mixed Dietary Fats during an Energy-Restricted Diet: Effects on Weight Loss, Serum Lipids, Fibrinogen, and Vascular Function. Nutrition, 21, 67-75. http://dx.doi.org/10.1016/j.nut.2004.09.010
[39] Sloth, B., Due, A., Larsen, T.M., Holst, J.J., Heding, A. and Astrup, A. (2009) The Effect of a High-MUFA, Low-Glycaemic Index Diet and a Low-Fat Diet on Appetite and Glucose Metabolism during a 6-Month Weight Maintenance Period. British Journal of Nutrition, 101, 1846-1858.
http://dx.doi.org/10.1017/S0007114508137710
[40] Champagne, C.M., Broyles, S.T., Moran, L.D., Cash, K.C., Levy, E.J., Lin, P.-H., et al. (2011) Dietary Intakes Associated with Successful Weight Loss and Maintenance during the Weight Loss Maintenance Trial. Journal of the American Dietetic Association, 111, 1826-1835.
http://dx.doi.org/10.1016/j.jada.2011.09.014
[41] Schmidt, M.S., Duncan, B.B., Azevedo e Silva, G., Menezes, A.M., Monteiro, C.A., Barreto, S.M., et al. (2011) Chronic Non-Communicable Diseases in Brazil: Burden and Current Challenges. Lancet, 377, 1949-1961. http://dx.doi.org/10.1016/S0140-6736(11)60135-9
[42] Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Bohm, M., et al. (2013) ESH/ESC Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 34, 2159-2219. http://dx.doi.org/10.1093/eurheartj/eht151
[43] Schwingshackl, L., Strasser, B. and Hoffmann, G. (2011) Effects of Monounsaturated Fatty Acids on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Annals of Nutrition and Metabolism, 59, 176-186. http://dx.doi.org/10.1159/000334071
[44] Ojewole, J.A., Kamadyaapa, D.R., Gondwe, M.M., Moodley, K. and Musabayane, C.T. (2007) Cardiovascular Effects of Persea americana Mill (Lauraceae) (Avocado) Aqueous Leaf Extract in Experimental Animals. Cardiovascular Journal of Africa, 18, 69-76.
[45] Adeboye, J.O., Fajonyomi, M.O., Makinde, J.M. and Taiwo, O.B. (1999) A Preliminary Study on the Hypotensive Activity of Persea americana Leaf Extracts in Anaesthetized, Normotensive Rats. Fitoterapia, 70, 15-20. http://dx.doi.org/10.1016/S0367-326X(98)00015-X
[46] Owolabi, M.A., Jaja, S.I. and Coker, H.A.B. (2005) Vasorelaxant Action of Aqueous Extract of the Leaves of Persea americana on Isolated Thoracic Rat Aorta. Fitoterapia, 76, 567-573.
http://dx.doi.org/10.1016/j.fitote.2005.04.020
[47] Imafidon, K.E. and Amaechina, F.C. (2010) Effects of Aqueous Seed Extract of Persea americana Mill. (Avocado) on Blood Pressure and Lipid Profile in Hypertensive Rats. Advances in Biological Research, 4, 116-121.

  
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