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Mapping the EQ-5D-5L Utility Scores: A Pilot Study in Orthopaedic Patients

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DOI: 10.4236/ojo.2015.54010    2,582 Downloads   3,050 Views  


Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor; it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT; they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.

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The authors declare no conflicts of interest.

Cite this paper

Hung, M. , Cheng, C. , Hon, S. and Bounsanga, J. (2015) Mapping the EQ-5D-5L Utility Scores: A Pilot Study in Orthopaedic Patients. Open Journal of Orthopedics, 5, 67-81. doi: 10.4236/ojo.2015.54010.


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