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Mediastinal Masses: Pathophysiological Issues and Management Challenges in a Developing World

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DOI: 10.4236/ss.2011.24047    4,500 Downloads   7,068 Views  


Context: Mediastinal masses occur worldwide. Compartmental occurrence and pathological variants vary widely, hence, the need for more studies. AIM: The study was conducted to further shed light on patho-physiological and current management challenges on mediastinal masses. Settings and Design: It was a pro-spective hospital based study spanning a period of 5 years. Methods and Materials: We gathered patients in series noting their ages and sex, presenting symptoms, investigation reports, treatment modalities and associ-ated postoperative complications. Statistical Analysis Used: Data was analysed manually looking at fre-quency distribution, correlation of malignancy with compartment involved and duration of symptoms against incidence of malignancy. Results: We saw 38 patients with significant male preponderance. Most tumours were in anterior mediastinum and population distribution was leptokurtic. Conclusions: Population distribu-tion of mediastinal masses is leptokurtic. The second to the fourth decades of life are mostly There was no correlation between occurrence of malignancy and the mediastinal compartment involved. Occurrence of malignancy had no bearing with duration of symptoms. affected. Most benign tumours are symptomatic and duration of symptoms is not discriminatory between benign and malignant variants. There is no correlation between occurrence of malignancy and the mediastinal compartment involved and occurrence of malignancy had no bearing with duration of symptoms.

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M. Thomas and E. Ogunleye, "Mediastinal Masses: Pathophysiological Issues and Management Challenges in a Developing World," Surgical Science, Vol. 2 No. 4, 2011, pp. 212-214. doi: 10.4236/ss.2011.24047.


[1] Zhang Y, yang SR, Cheng DU, Guan J. Clinical and pathological features of congenital bronchial cyst. Zhonghua Jie He He Hu Xi Za Zhi. 2003; 26(10): 619- 622.
[2] Cheng LH, Wells FC. A multidisciplinary approach to recurrent cervicothoracic cystic hygroma in an adult. Br J Maxillofac Surg 2004; 42(1): 66-68.
[3] Adzick NS. Management of foetal lung lesions. Clin Perinatol 2003; 30(3):481-492.
[4] Kim JH, Goo JM, Lee HJ, Chung MJ, Jung SI, Lim KY, Lee MW, Im JG. Cystic tumours in the anterior mediastinum. Radiologic-pathological correlation. J Comput Assist Tomogr 2003; 27(5): 714-723
[5] Ankermann T, Claviez A, Suttorp M. Mediastinal tumour in children initially misdiagnosed and treated as bronchial asthma. Dtsch Med Wochenschr 2004; 129(12): 613-616.
[6] Lam JC, Chui CH, Jacobsen AS, Tan AM, Joseph VT. When is a mediastinal mass critical in a child? An analysis of 29 patients. Pediatr Surg Int 2004; 20: 180-184.
[7] Adegboye VO, Ogunsehinde AO,Obajimi MO,Ogunbiyi O, Brimmo AI, Adebo OA. Presentation of primary mediastinal masses in Ibadan. East Afr Med J 2003; 80(9): 484-487.
[8] Krober SM, Marx A, Aebert H, Dohmen BM, Kaiserling E. Sarcoma of follicular dendritic cells in the dorsal mediastinum. Hum Pathol 2004; 35(2): 259-263.
[9] Al-Marzooq YM, Al-Bahrani AT, Chopra R, Al-Momatten MI. Fine needle aspiration biopsy diagnosis of intrathoracic extramedullary hematopoiesis presenting as a posterior mediastinal tumour in a patient with sickle-cell disease: Case report. Diagn Cytopathol 2004; 30(2): 119-121.
[10] Irabor DO, Ladipo JK, Nwachokor FN, Thomas JO. Schwannoma of the left branchial plexus mimicking a cervicomediastinal gotre in ayoung Nigerian lady. West Afr J Med 2002; 21(3): 195-196.
[11] Plaza JA, Dominguez F, Suster S. Cystic adenomatous tumour of the mediastinum. Am J Surg Pathol 2004; 28(1): 132-138.
[12] Pramesh CS, Deshpande MS, Pantvaidya GH, Sharma S, Deshpande RK. Thoracic duct cyst of the mediastinum. Ann Thorac Cardiovasc Surg 2003; 9(4): 264-265.
[13] Adegboye VO, Brimmo AI, Adebo OA, Ogunsehinde OO, Obajimi MO. The place of clinical features and standard chest radiography in evaluation of mediastinal masses. West Afr J Med 2003; 22(2): 156-160.
[14] Morgan JA, Kohmoto T, Smith CR, Oz MC, Argeziano M. Endoscopic computer-enhanced mediastinal mass resection using robotic technology. Heart Surg forum 2003; 6(6): E164-166.

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