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Influence of the Multispecies Probiotic Ecologic® BARRIER on Parameters of Intestinal Barrier Function

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DOI: 10.4236/fns.2014.518187    2,428 Downloads   3,335 Views   Citations

ABSTRACT

The intestinal epithelium is a single cell layer that forms the largest and most important barrier against the external environment. A proper functioning of the intestinal barrier is essential for maintaining optimal health. A disrupted intestinal barrier function has been associated with the development of autoimmune and inflammatory diseases. Probiotics are live microorganisms that confer a health benefit to the host and have been associated with prevention of diseases such as antibiotic-associated diarrhea, irritable bowel syndrome and inflammatory bowel disease. Probiotics can improve and restore the intestinal barrier function in diverse ways and effects are thought to be species- and even strain-specific. With this research the influence of probiotic bacteria in Ecologic? BARRIER on parameters of intestinal barrier function was investigated. The results show that each bacterial strain in Ecologic?BARRIER is in vitro capable to improve the epithelial barrier in diverse ways.

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Hemert, S. and Ormel, G. (2014) Influence of the Multispecies Probiotic Ecologic® BARRIER on Parameters of Intestinal Barrier Function. Food and Nutrition Sciences, 5, 1739-1745. doi: 10.4236/fns.2014.518187.

References

[1] Farhadi, A., Banan, A., Fields, J. and Keshavarzian, A. (2003) Intestinal Barrier: An Interface between Health and Disease. Journal of Gastroenterology and Hepatology, 18, 479-497.
http://dx.doi.org/10.1046/j.1440-1746.2003.03032.x
[2] Marchiando, A.M., Graham, W.V. and Turner, J.R. (2010) Epithelial Barriers in Homeostasis and Disease. Annual Review of Pathology-Mechanisms of Disease, 5, 119-144.
[3] Ohland, C.L. and Macnaughton, W.K. (2010) Probiotic Bacteria and Intestinal Epithelial Barrier Function. American Journal of Physiology. Gastrointestinal and Liver Physiology, 298, G807-G819.
[4] Hill. C., et al. (2014) The International Scientific Association for Probiotics and Prebiotics Consensus Statement on the Scope and Appropriate Use of the Term Probiotic. Nature Reviews Gastroenterology & Hepatology, 11, 506-514.
[5] Miyauchi, E., et al. (2012) Mechanism of Protection of Transepithelial Barrier Function by Lactobacillus Salivarius: Strain-Dependence and Attenuation by Bacteriocin Production. American Journal of Physiology and Gastrointestinal Liver Physiology, 303, G1029-G1104.
http://dx.doi.org/10.1152/ajpgi.00003.2012
[6] van Hemert, S., Verwer, J. and Schütz, B. (2013) Clinical Studies Evaluation Effects of Probiotics on Parameters of Intestinal Barrier Function. Advances in Microbiology, 3, 212-221,
[7] Zheng, P.Y., Feng, B.S., Oluwole, C., Struiksma, S., Chen, X., Li, P., Tang, S.G. and Yang, P.C. (2009) Psychological Stress Induces Eosinophils to Produce Corticotrophin Releasing Hormone in the Intestine. Gut, 58, 1473-1479.
http://dx.doi.org/10.1136/gut.2009.181701
[8] Lutgendorff, F. (2009) Defending the Barrier. Effects of Probiotic on Endogenous Defens Mechanims. Universiteit Utrecht, Utrecht.
[9] Hooper, L.V. and Gordon, J.I. (2001) Commensal Host-Bacterial Relationships in the Gut. Science, 292, 1115-1118.
http://dx.doi.org/10.1126/science.1058709
[10] Delcenserie, V., Martel, D., Lamoureux, M., Amiot, J., Boutin, Y. and Roy, D. (2008) Immunomodulatory Effects of Probiotics in the Intestinal Tract. Current Issues in Molecular Biology, 10, 37-54.
[11] Gill, H. and Prasad, J. (2008) Probiotics, Immunomodulation, and Health Benefits. Advances in Experimental Medicine and Biology, 606, 423-454.
[12] Nova, E., Warnberg, J., Gomez-Martinez, S., Diaz, L.E., Romeo, J. and Marcos, A. (2007) Immunomodulatory Effects of Probiotics in Different Stages of Life. British Journal of Nutrition, 98, S90-S95.

  
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