CRCM> Vol.3 No.8, August 2014
Review Paper

Clinically Diagnosed Guillain-Barre Syndrome in Pregnancy: Case Report and Review of Literature

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ABSTRACT

Background: Guillain-Barre syndrome (GBS) is an autoimmune disorder characterized by a heterogeneous group of pathological and clinical entities. It is associated with ascending areflexic paralysis, some autonomic dysfunction and respiratory failure in severe cases and ultimately death if not promptly diagnosed and treated. It may be preceded by an antecedent event in about two-third of cases. This could be an upper respiratory tract infection, viral illness, recent history of vaccination, pregnancy, cancer or even trauma. The condition is exceedingly rare in pregnancy and only few cases have been reported in literature. Case Report: This is a case of a 28-year-old Gravida 3, Para 1+1 and Estimated Gestational Age of 30 weeks and 4 days. There was a history of upper respiratory tract infection eight weeks prior to presentation which spontaneously resolved. On examination, she was a young woman, anxious, weak, afebrile, not pale, the neck could not hold the head upright and there was bilateral non tender pitting pedal oedema extending to her mid-shin. There were no cranial nerve deficits and no sign of meningeal irritation. There were normal muscle bulk with global hypotonia and flaccid quadriparesis, Power was 3/5. The proximal groups of muscles were more affected than the distal parts. Reflexes were diminished globally with plantar flexor response. She had immunoglobulin as treatment. Conclusion: In a low resource setting like ours it is important to have a high index of suspicion of GBS when an apparently healthy gravid woman presents with progressive weakness of the limbs.

Cite this paper

Koledade, A. , Oguntayo, A. , Abubakar, S. , Katung, G. and Shittu, S. (2014) Clinically Diagnosed Guillain-Barre Syndrome in Pregnancy: Case Report and Review of Literature. Case Reports in Clinical Medicine, 3, 487-490. doi: 10.4236/crcm.2014.38106.

References

[1] Seneviratne, U. (2000) Guillain-Barre Syndrome. Postgraduate Medical Journal, 76, 774-782.
http://pmj.bmj.com/content/76/902/774.full
[2] Zeeman, G.G. (2001) A Case of Acute Inflammatory Demyelinating Polyradiculoneuropathy in Early Pregnancy. American Journal of Perinatology, 18, 213-215.
[3] Soliven, B. and Roos, R.P. (2013) Neurology Medlink.
http://www.medlink.com/medlinkcontent.asp
[4] Vasudev, R. and Raina, T.R. (2014) A Rare Case of Guillain-Barré Syndrome in Pregnancy Treated with Plasma Exchange. Asian Journal of Transfusion Science, 8, 59-60.
http://www.ajts.org/article.asp?issn=0973-6247;year=2014;volume=8;issue=1;spage=59;
epage=60;aulast=Vasudev
[5] Owolabi, L.F., Ibrahim A., Samaila A.A. (2011) Profile and Outcome of Non-Traumatic Paraplegia in Kano, Northwestern Nigeria. Annals of African Medicine, 10, 86-90.
http://www.annalsafrmed.org/article.asp?issn=1596-3519;year=2011;volume=10;issue=2;
spage=86;epage=90;aulast=Owolabi
[6] Zafar, M.S.H., Naqash, M.M., Bhat, T.A. and Malik, G.M. (2013) Guillain-Barré Syndrome in Pregnancy: An Unusual Case. Journal of Family Medicine and Primary Care, 2, 90-91.
http://www.jfmpc.com/article.asp?issn=2249-4863;year=2013;volume=2;issue=1;spage=90;
epage=91;aulast=Zafar
[7] Furara, S., Maw, M., Khan, F. and Powell, K. (2008) Weakness in Pregnancy-Expect the Unexpected. Obstetric Medicine, 1, 99-101.
http://dx.doi.org/10.1258/om.2008.080011
[8] Elovaara, I., Apostolski, S., Van Doorn, P., Gilhus, N.E., Hietaharju, A., Honkaniemi, J., et al. (2008) EFNS Guidelines for the Use of Intravenous Immunoglobulin in Treatment of Neurological Diseases: EFNS Task Force on the Use of Intravenous Immunoglobulin in Treatment of Neurological Diseases. European Journal of Neurology, 15, 893-908.
http://www.ncbi.nlm.nih.gov/pubmed/18796075

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