AAD> Vol.3 No.2, June 2014

Prevalence of Dementia and Its Associated Factors in Cotonou Teaching Hospital, Benin

DownloadDownload as PDF (Size:369KB)  HTML   XML  PP. 94-106  

ABSTRACT

Introduction: Dementia constitutes a public health hazard in developing countries. There is little data in the sub-Saharan region of African especially in Benin. Objective: Determining dementia hospitalization prevalence and identifying its associated factors in CNHU-HKM, Cotonou. Method: It was a cross-sectional, prospective, descriptive and analytical research conducted from October 2012 to July 2013 in the neurology department; it involved 251 patients aged 50 and above. Dementia screening was conducted using a modified and adapted Mini Mental Scale Examination (MMSE). Dementia clinical and etiological diagnoses were respectively conducted based on DMS-IV and HACHINSKI criteria. Results: Patients were averagely aged 60.9 ± 8.1. Sex ratio (Male/Female) was 1.07. Dementia prevalence was 8.8%. This rate increased proportionally with age, from 5.3% with patients aged below 60 to 12.7% with patients aged above 60. Degenerative dementia was the most predominant type (50%). Following multi-varied analysis, smoking (RC = 6.05 [IC 95% = 1.26 - 29.38] p = 0.0001) and stroke past records (RC = 6.05 [IC 95% = 1.26 - 29.38] p = 0.001) revealed to be the factors associated with dementia. Conclusion: This research showed that dementia affects a significant part of the aging population in CNHU-HKM. It is imperative to combat its associated factors so as to defuse its prevalence.

Cite this paper

Gnonlonfoun, D. , Adjien, C. , Ossou-Nguiet, P. , Diallo, L. , Houannou, O. , Acakpo, J. , Goudjinou, G. , Houinato, D. and Avode, D. (2014) Prevalence of Dementia and Its Associated Factors in Cotonou Teaching Hospital, Benin. Advances in Alzheimer's Disease, 3, 94-106. doi: 10.4236/aad.2014.32010.

References

[1] Napon, C., Traore, S., Idris, S., Niakara, A., Ouango, G.G., Kabré, A., et al. (2009) Dementia in Sub-Saharan Africa: Clinic and Etiological Aspects in Ouagadougou Hospital (Burkina Faso). African Journal of Neurological Sciences, 28, 1-5.
[2] Ferri, C.P. (2005) Global Prevalence of Dementia. Delphy Consensus Study, 366, 2112-2117.
[3] Baiyewu, O., Bella, A.F., Adeyemi, J.D., Bamgboye, E.A., Ikuesan, B.A. and Jegede, R.O. (1997) Health Problems and Socio-Demographic Findings in Elderly Nigerians. African Journal of Medicine and Medical Sciences, 2, 13-17.
[4] Touré, K., Coumé, M., Ndiaye-Ndongo, N.D., Thiam, M.H., Zunzunegui, M.V., Bacher, Y., et al. (2008) Dementia Prevalence in a Senegalese Elderly Population. African Journal of Neurological Sciences, 27, 15-22.
[5] Avode, D.G., Gandaho, P., Da-Cruz, P.C., Ahyi, R.G. and Zohoun, Th. (1998) Senile Dementia in Cotonou Hospital. Le Bénin Médical, 7, 23-27.
[6] Paraiso, M.N. (2010) Dementia Epidemiology in Elderly Benin Population Aged 65 and Above (Afrique de l’Ouest). Ph.D. Heath Science Biology. University of Limoges, Limoges, 486p.
[7] Coume, M., Touré, K., Thiam, M.H., Zunzunegui, M.V., Bacher, Y., Diop, T.M., et al. (2012) Evaluation of Cognitive Deficiency Prevalence in Elderly Population in a Senegalese Health Center “Institution Retraite”. Geriatr Psychol Neuropsychiatr Vieil, 10, 39-46.
[8] Mbelesso, P., Tabo, A., Guerchet, M., Mouanga, A.M., Bandzouzi, B., Houinato, D., et al. (2012) Dementia Epidemiology in Elderly Population Living in Bangui 3rd Municipality (Central Africa Republic)]. Bulletin de la Société de pathologie exotique, 105, 388-395. http://dx.doi.org/10.1007/s13149-012-0247-8
[9] Molero, A.E., Pino-Ramirez, G. and Maestre, G.E. (2007) High Prevalence of Dementia in a Caribbean Population. Neuroepidemiology, 29, 107-112. http://dx.doi.org/10.1159/000109824
[10] Uwakwe, R., Ibeh, C.C., Modebe, A.I., Bo, E., Ezeama, N., Njelita, I., et al. (2009) Dependence Epidemiology in Elderly Population in Nigeria: Prevalence, Determinants, Informal Care and the Use of Health Services; Research Group 10/66 Dementia. Journal of the American Geriatrics Society, 57, 1620-1627. http://dx.doi.org/10.1111/j.1532-5415.2009.02397.x
[11] Ndiaye, N.N.D., Sylla, A., Touré, K., Thiam, M.H. and Gueye, M. (2011) Operations Assessment in a Senegalese Memory Clinic, Fann Teaching Hospital Psychiatric Department (Dakar, Senegal). African Journal of Neurological Sciences, 30, 2-10.
[12] Guerchet, M., Houinato, D., Paraiso, M.N., von-Ahsen, N., Nubukpo, P., Otto, M., et al. (2009) Dementia and Cognitive Disorders in Elderly Population Living in Benin Rural Areas, West Africa. Dementia and Geriatric Cognitive Disorders, 27, 34-41. http://dx.doi.org/10.1159/000188661
[13] Longdon, A.R., Paddick, S.M., Kisoli, A., Dotchin, C., Gris, W.K., Dewhurst, F., et al. (2013) Dementia Prevalence in Rural Tanzania: A Community Cross-Sectional Research. International Journal of Geriatric Psychiatry, 28, 728-737. http://dx.doi.org/10.1002/gps.3880
[14] El-Tallawy, H.N., Farghly, W.M., Shehata, G.A., Rageh, T.A., Hakeem, N.A., Abo-Elfetoh, N., et al. (2012) Dementia Prevalence in Kharga District Al, New Valley Governorate, Egypt. Neuroepidemiology, 38, 130-137. http://dx.doi.org/10.1159/000335655
[15] Yusuf, A.J., Baiyewu, O., Sheikh, T.L. and Shehu, U.A. (2011) Prevalence of Dementia and Sub-Types of Dementia in a Northern Nigerian Elderly Population. International Psychogeriatrics, 3, 379-386. http://dx.doi.org/10.1017/S1041610210001158
[16] Llibre-Rodriguez, J.J., Ferri, C.P., Acosta, D., Guerra, M., Huang, Y., Jacob, K.S., et al. (2008) 10/66 Dementia Research Group. Prevalence of Dementia in Latin America, India, and China: A Population-Based Cross-Sectional Survey. Lancet, 372, 464-474. http://dx.doi.org/10.1016/S0140-6736(08)61002-8
[17] Stewart, R., Kim, J., Shin, S. and Yoon, J. (2003) Education and the Association between Vascular Risk Factors and Cognitive Function. A Cross-Sectional Study in Older Koreans with Cognitive Impairment. International Psychogeriatrics, 15, 27-36. http://dx.doi.org/10.1017/S1041610203008731
[18] Letenneur, L., Gilleron, V., Commenges, D., Helmer, C., Orgogozo, J.M. and Dartigues, J.F. (1999) Are Sex and Educational Level Independent Predictors of Dementia and Alzheimer’s Disease? Incidence Data from the PAQUID Project. Journal of Neurology, Neurosurgery & Psychiatry, 66, 177-183. http://dx.doi.org/10.1136/jnnp.66.2.177
[19] Nitrini, R., Caramelli, P., Herrera, E., Bahia, V.S., Caixeta, L.F., Radanovic, M., et al. (2004) Incidence of Dementia in A Community-Dwelling Brazilian Population. Alzheimer Disease and Associated Disorders, 18, 241-246.
[20] Fratiglioni, L., Paillard-Borg, S. and Winblad, B. (2004) An Active and Socially Integrated Lifestyle in Late Life Might Protect against Dementia. The Lancet Neurology, 3, 343-353. http://dx.doi.org/10.1016/S1474-4422(04)00767-7
[21] Van-Gelder, B,M., Tijhuis, M., Kalmijn, S., Giampaoli, S., Nissinen, A. and Kromhou, D. (2006) Marital Status and Living Situation During a 5-Year Period Are Associated With a Subsequent 10-Year Cognitive Decline in Older Men: The FINE Study. The Journals of Gerontology, 61, 213-219. http://dx.doi.org/10.1093/geronb/61.4.P213
[22] Chen, C.H., Mizuno, T., Elston, R., Kariuki, M.M., Hall, K., Unverzagt, F., et al. (2010) Comparative Study to Screen Dementia and APOE Genotypes in an Ageing East African population. Neurobiology Aging, 31, 732-740. http://dx.doi.org/10.1093/geronb/61.4.P213
[23] Shelley, B.P. and Al-Khabouri, J. (2007) Dementia Spectrum: Prevalence, Causes and Clinic Profile. A National Reference; Research in Oman Hosptial. Dementia and Geriatric Cognitive Disorders, 24, 280-287. http://dx.doi.org/10.1159/000107494
[24] Alladi, S., Mekala, S., Chadalawada, S.K., Jala, S., Mridula, R. and Kaul, S. (2011) Dementia Subtypes Divisions: A Study from an Indian Memory Clinic. Dementia and Geriatric Cognitive Disorders, 32, 32-38. http://dx.doi.org/10.1159/000329862
[25] Pendlebury, S.T. (2012) Dementia in Patients Hospitalized with Stroke: Rates, Time Course, and Clinico-Pathologic Factors. International Journal of Stroke, 7, 570-581.
[26] Altieri, M., Di-Piero, V., Pasquini, M., Gasparini, M., Vanacore, N., Vicenzini, E., et al. (2004) Delayed Post Stroke Dementia. A 4-Year Follow-Up Study. Neurology, 62, 2193-2197.
http://dx.doi.org/10.1212/01.WNL.0000130501.79012.1A
[27] Pasquier, F. and Leys, D. (1997) Post Stroke Dementia Mechanism. Blood Thrombosis Vessels, 9, 220-226.
[28] Juan, D., Zhou, D.H., Li, J., Wang, J.Y., Gao, C. and Chen M.A. (2004) 2-Year Follow-Up Study of Cigarette Smoking and Risk of Dementia. European Journal of Neurology, 11, 277-282.
http://dx.doi.org/10.1212/01.WNL.0000130501.79012.1A
[29] Rusanen, M., Kivipelto, M., Quesenberry, C.P. and Whitmer, R.A. (2011) Heavy Smoking in Midlife and Long-Term Risk of Alzheimer Disease and Vascular Dementia. JAMA Internal Medicine, 171, 333-339.
[30] Dong, M.J., Peng, B., Lin, X.T., Zhao, J., Zhou, Y.R. and Wang, R.H. (2007) The Prevalence of Dementia in the People’s Republic of China: A Systematic Analysis of 1980-2004 Studies. Age Ageing, 36, 619-624. http://dx.doi.org/10.1093/ageing/afm128

comments powered by Disqus

Copyright © 2014 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.