Feeding Study with Bt Corn (MON810: Ajeeb YG) on Rats: Biochemical Analysis and Liver Histopathology

Eman Mohamed Abdo, Omar Mohamed Barbary, Omayma El-Sayed Shaltout

Food Science Department, Faculty of Agriculture (Saba-Basha), Alexandria University, Alexandria, Egypt..

DOI: 10.4236/fns.2014.52024                

Abstract

Bt corn “MON810: Ajeeb YG” produces delta endotoxins in the whole plant due to the genetic modification process. The chemical analysis of this variety showed significant differences from its conventional counterpart “Ajeeb”. Further, feeding studies on rats were designed to complete assessing the safety of “MON810: Ajeeb YG”. Three groups of rats (6 males and 6 females’ rats/group) were fed on control diet, non-Bt corn and Bt corn for 1.5 months and 3 months. After 1.5 months, 3 males and 3 females from each group were sacrificed, and after another 1.5 months, 3 males and 3 females from each group and their offspring were sacrificed. Histopathological examination, blood haematology and serum biochemical analysis were determined. Results indicated significant differences among the tested parameters in the three groups especially Bt group. Severe changes in the liver of Bt group after 3 months were observed.

Keywords

MON810: Ajeeb YG; Feeding Study; Blood Biochemical Analysis; Haematology; Histopathology

Conflicts of Interest

The authors declare no conflicts of interest.

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