Health> Vol.6 No.1, January 2014

Influence of hyperbaric oxygenation treatment (HBOT) on clinical outcomes (recurrent myocardial infarction and survival rate) during five-year monitoring period after acute myocardial infarction

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ABSTRACT

Surgical treatments of acute myocardial infarction (MI) possess a high clinical effectiveness, but there are fixed limitations, related to the patient’s state, which are limited by medical resources and organizational problems. The development of new medical technologies provides a better and effective non-surgical treatment of acute MI and increases long-term prognosis in this category of patients. The study aims to investigate the influence of hyperbaric oxygenation treatment on clinical outcomes (survival rate and recurrent myocardial infarction (rMI)) during the five-year period of monitoring. The study involved 697 patients who suffered from acute MI, having undergone the standard treatment. The patients were randomly divided into two groups: Group 1 (reference, n = 363); Group 2 (test, n = 334). Patients of Group 2 were given the traditional treatment, accompanied with HBOT (isopression for forty minutes at a working pressure of 0.03 MPa). HBOT was applied first through the fifth day following MI. The treatment course included six cycles, once per day. The clinical assessment was focused on clinical outcome: rMI and mortality related to cardiovascular events. HBOT application that accompanied the acute MI with traditional pharmacotherapy has been proved to reduce rMI within five years following inpatient discharge (rMI rate was 14% in the reference group and 5.4% in the test group, χ2 = 13.3, р < 0.05). The combination of HBOT with traditional methods in treating acute MI makes it possible to raise the five-year survival rate from 84.4% up to 95.9%.

Cite this paper

Dotsenko, E. , Salivonchyk, D. , Welcome, O. , Dotsenko, K. , Salivonchyk, S. , Bobkov, V. , Nikulina, N. , Semeniago, E. and Nerobeeva, S. (2014) Influence of hyperbaric oxygenation treatment (HBOT) on clinical outcomes (recurrent myocardial infarction and survival rate) during five-year monitoring period after acute myocardial infarction. Health, 6, 51-56. doi: 10.4236/health.2014.61008.

References

[1] Dutta, P., Courties, G., Wei, Y., Leuschner, F., Gorbatov, R., Robbins, C.S., Iwamoto, Y., Thompson, B., Carlson, A.L., Heidt, T., Majmudar, M.D., Lasitschka, F., Etzrodt, M., Waterman, P., Waring, M.T., Chicoine, A.T., van der Laan, A.M., Niessen, H.W., Piek, J.J., Rubin, B.B., Butany, J., Stone, J.R., Katus, H.A., Murphy, S.A., Morrow, D.A., Sabatine, M.S., Vinegoni, C., Moskowitz, M.A., Pittet, M.J., Libby, P., Lin, C.P., Swirski, F.K., Weissleder, R. and Nahrendorf, M. (2012) Myocardial infarction accelerates atherosclerosis. Nature, 487, 325-329.
http://dx.doi.org/10.1038/nature11260
[2] Madrigano, J., Mittleman, M.A., Baccarelli, A., Goldberg, R., Melly, S., von Klot, S. and Schwartz J. (2013) Temperature, myocardial infarction, and mortality: Effect modification by individualand area-level characteristics. Epidemiology, 24, 439-446.
http://dx.doi.org/10.1097/EDE.0b013e3182878397
[3] Qian, G., Liu, H.-B., Wang, J.-W., Wu, C. and Chen, Y.-D. (2013) Risk of cardiac rupture after acute myocardial infarction is related to a risk of hemorrhage. Journal of Zhejiang University—SCIENCE B (Biomedicine & Biotechnology), 14, 736-742.
[4] Yeh, R.W., Sidney, S., Chandra, M., Sorel, M., Selby, J.V. and Go, A.S. (2010) Population trends in the incidence and outcomes of acute myocardial infarction. New England Journal of Medicine, 362, 2155-2165.
http://dx.doi.org/10.1056/NEJMoa0908610
[5] van Oeffelen, A.A., Vaartjes, I., Stronks, K., Bots, M.L. and Agyemang, C. (2013) Incidence of acute myocardial infarction in first and second generation minority groups: Does the second generation converge towards the majority population? International Journal of Cardiology, 168, 5422-5429. http://dx.doi.org/10.1016/j.ijcard.2013.08.046
[6] Laatikainen, T., Critchley, J., Vartiainen, E., Salomaa, V., Ketonen, M. and Capewell, S. (2005) Explaining the decline in coronary heart disease mortality in Finland between 1982 and 1997. American Journal of Epidemiology, 162, 764-773. http://dx.doi.org/10.1093/aje/kwi274
[7] Capewell, S., Unal, B., Critchley, J.A. and McMurray, J.J.V. (2006) Over 20000 avoidable coronary deaths in England and Wales in 2000: The failure to give effective treatments to many eligible patients. Heart, 92, 521-523.
http://dx.doi.org/10.1136/hrt.2004.053645
[8] Murphy, N.F., MacIntyre, K., Stewart, S., Capewell, S. and McMurray, J.J.V. (2005) Reduced between-hospital variation in short term survival after acute myocardial infarction: The result of improved cardiac care? Heart, 91, 726-730. http://dx.doi.org/10.1136/hrt.2004.042929
[9] Giorda, C.B., Avogaro, A., Maggini, M., Lombardo, F., Mannucci, E., Turco, S., Alegiani, S.S., Raschetti, R., Velussi, M. and Ferrannini, E. (2008) Recurrence of cardiovascular events in patients with type 2 diabetes. Diabetes Care, 31, 2154-2159.
[10] Launbjerg, J., Fruergaard, P., Madsen, J.K., Mortensen, L.S. and Hansen, J.F. (1994) Ten year mortality in patients with suspected acute myocardial infarction. British Medical Journal, 308, 1196-1199.
http://dx.doi.org/10.1136/bmj.308.6938.1196
[11] Goldberg, R.J., Yarzebski, J., Lessard, D. and Gore, J.M. (1999) A two-decade (1975-1995) long experience in incidence, in-hospital and long term case-fatality rates of acute myocardial infarction: A community-wide perspective. Journal of the American College of Cardiology, 33, 1533-1539.
http://dx.doi.org/10.1016/S0735-1097(99)00040-6
[12] Capewell, S., Livingston, B.M., MacIntyre, K., Chalmers, J.W., Boyd, J., Finlayson, A., Redpath, A., Pell, J.P., Evans, C.J. and McMurray, J.J. (2000) Trends in casefatality in 117718 patients admitted with acute myocardial infarction in Scotland. European Heart Journal, 21, 1833-1840. http://dx.doi.org/10.1053/euhj.2000.2318
[13] Ulvenstam, G., Aberg, A., Bergstrand, R., Johansson, S., Pennert, K., Vedin, A., Wedel, H., Wilhelmsen, L. and Wilhelmsson, C. (1985) Recurrent myocardial infarction. 1. Natural history of fatal and non-fatal events. European Heart Journal, 6, 294-302.
[14] Ulvenstam, G., Aberg, A., Pennert, K., Vedin, A., Wedel, H., Wilhelmsen, L. and Wilhelmsson, C. (1985) Recurrent myocardial infarction, 2: Possibilities of prediction. European Heart Journal, 6, 303-311.
[15] Madsen, J.K., Grande, P., Saunamaki, K., Thayssen, P., Kassis, E., Eriksen, U., Rasmussen, K., Haunso, S., Nielsen, T.T., Haghfelt, T., Fritz-Hansen, P., Hjelms, E., Paulsen, P.K., Alstrup, P., Arendrup, H., Niebuhr-Jorgensen, U. and Andersen, L.I. (1997) Danish Multicenter randomized study of invasive versus conservative treatment in patients with inducible ischemia after thrombolysis in acute myocardial infarction (DANAMI). Circulation, 96, 748-755. http://dx.doi.org/10.1161/01.CIR.96.3.748
[16] Vaccarino, V., Berkman, L.F. and Krumholz, H.M. (2000) Long-term outcome of myocardial infarction in women and men: A Population Perspective. American Journal of Epidemiology, 152, 965-973.
http://dx.doi.org/10.1093/aje/152.10.965
[17] Nikulina, N.V., Dotsenko, E.A., Salivonchyk, D.P., Welcome, M.O., Lappo, O.G., Dotsenko, K.E. and Bobkov V.Ya. (2013) Low doses hypoxia effectively reduces the size of necrosis in rats with experimental myocardial infarction. World Journal of Medical Sciences, 9, 88-92.
[18] Nylander, G., Nordstrom, H., Franzén, L., Henriksson, K.-G. and Larsson, J. (1988) Effect of hyperbaric oxygen treatment in post-ischemic muscle: A quantitative morphological study. Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, 22, 31-39.
http://dx.doi.org/10.3109/02844318809097932
[19] van Poucke, S., Jorens, P. and Beaucourt, L. (2006) Physiological effects of hyperbaric oxygen on ischemia reperfusion phenomenon. In: Mathieu, D., Ed., Handbook on hyperbaric Medicine, Springer, Berlin, 121-134.
http://dx.doi.org/10.1007/1-4020-4448-8_8
[20] Tabrah, F.L., Tanner, R., Vega, R. and Batkin, S. (1994) Ваrоmedicine today—Rational uses of hyperbaric oxygen therapy. Hawaii Medical Journal, 53, 112-119.
[21] Wattle, F. (2006) A history of hyperbaric medicine. In: Mathieu, D., Ed., Handbook on Hyperbaric Medicine, Springer, Berlin, 1-11.
http://dx.doi.org/10.1007/1-4020-4448-8_1
[22] Ingle, R. (1990) Hyperbaric oxygen therapy. Journal of the American Medical Association, 264, 1811.
http://dx.doi.org/10.1001/jama.1990.03450140031024
[23] Yin, X., Meng, F., Wang, Y., Wei, W., Li, A., Chai, Y. and Feng, Z. (2013) Effect of hyperbaric oxygen on neurological recovery of neonatal rats following hypoxicischemic brain damage and its underlying mechanism. International Journal of Clinical and Experimental Pathology, 6, 66-75.
[24] Efrati, S., Fishlev, G., Bechor, Y., Volkov, O., Bergan, J., Kliakhandler, K., Kamiager, I., Gal, N., Friedman, M., Ben-Jacob, E. and Golan, H. (2013) Hyperbaric oxygen induces late neuroplasticity in post stroke patients—Randomized, prospective trial. PLoS ONE, 8, e53716.
http://dx.doi.org/10.1371/journal.pone.0053716
[25] Clower, J.H., Hampson, N.B., Iqbal, S. and Yip, F.Y. (2012) Recipients of hyperbaric oxygen treatment for carbon monoxide poisoning and exposure circumstances. American Journal of Emergency Medicine, 30, 846-851.
http://dx.doi.org/10.1016/j.ajem.2011.05.028
[26] Rossignol, D.A. (2012) Hyperbaric oxygen treatment for inflammatory bowel disease: A systematic review and analysis. Medical Gas Research, 2, 6.
http://dx.doi.org/10.1186/2045-9912-2-6
[27] Leach, R.M., Rees, P.J. and Wilmshurst, P. (1998) ABC of oxygen: Hyperbaric oxygen therapy. British Medical Journal, 317, 1140-1143.
http://dx.doi.org/10.1136/bmj.317.7166.1140
[28] Stavitsky, Y., Shandling, A.H., Ellestad, M.H., Hart, G.B., Van Natta, B., Messenger, J.C., Strauss, M., Dekleva, M.N., Alexander, J.M., Mattice, M. and Clarke, D. (1998) Hyperbaric oxygen and thrombolysis in myocardial infarction: The “HOT MI” randomized multicenter study. Cardiology, 90, 131-136.
http://dx.doi.org/10.1159/000006832
[29] Schmutz, J. (2006) Myocardial infarction. In: Mathieu, D., Ed., Handbook on Hyperbaric Medicine, Springer, Berlin, 591-595. http://dx.doi.org/10.1007/1-4020-4448-8_35
[30] European Society of Cardiology, American College of Cardiology (2002) Myocardial infarction redefined—A consensus document of the joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction. European Heart Journal, 21, 1502-1513.
[31] Ferguson, J.L., Beckett, G.J., Stoddart, M., Walker, S.W. and Fox, K.A. (2002) Myocardial infarction redefined: The new ACC/ESC definition, based on cardiac troponin, increases the apparent incidence of infarction. Heart, 88, 343-347. http://dx.doi.org/10.1136/heart.88.4.343
[32] Report of the Joint International Society and Federation of Cardiology/World Health Organization Task Force on Standardization of Clinical Nomenclature (1979) Nomenclature and Criteria for Diagnosis of Ischemic Heart Disease. Circulation, 59, 607-609.
http://dx.doi.org/10.1161/01.CIR.59.3.607
[33] Roe, M.T., Parsons, L.S., Pollack Jr., C.V., Canto, J.G., Barron, H.V., Every, N.R., Rogers, W.J. and Peterson, E.D. (2005) Quality of care by classification of myocardial infarction: Treatment patterns for ST-segment elevation vs non-ST-segment elevation myocardial infarction. Archives of Internal Medicine, 165, 1630-1636.
http://dx.doi.org/10.1001/archinte.165.14.1630
[34] Dotsenko, E.A., Salivonchyk, D., Nikulina, N. and Welcome, M.O. (2009) The influence of hyperbaric oxygenation therapy on recurrent myocardial infarction and twoyear survival rate with acute myocardial infarction patients. Port-Harcourt Medical Journal, 3, 256-263.
http://dx.doi.org/10.4314/phmedj.v3i3.45267
[35] Lai, T., Fallon, J.T., Liu, J., Mangion, J., Gillam, L., Waters, D. and Chen C. (2000) Reversibility and pathohistological basis of left ventricular remodeling in hibernating myocardium. Cardiovascular Pathology, 9, 323-335.
http://dx.doi.org/10.1016/S1054-8807(00)00052-1
[36] Imperatore, F., Cuzzocrea, S., De Lucia, D., Sessa, M., Rinaldi, B., Capuano, A., Liguori, G., Filippelli, A. and Rossi, F. (2006) Hyperbaric oxygen therapy prevents coagulation disorders in experimental model of multiple organ failure syndrome. Intensive Care Medicine, 32, 1881-1888. http://dx.doi.org/10.1007/s00134-006-0367-3
[37] dos Santos, L., Serra, A.J., Antonio, E.L., Hull, H.F. and Tucci, P.J. (2009) Hyperbaric oxygenation applied immediately after coronary occlusion reduces myocardial necrosis and acute mortality in rats. Clinical and Experimental Pharmacology and Physiology, 36, 594-598.
http://dx.doi.org/10.1111/j.1440-1681.2008.05118.x
[38] Mathieu, D., Mathieu-Nolf, M., Linke, J.C., Favory, R. and Wattel, F. (2006) Carbon monoxide poisoning. In: Mathieu, D., Ed., Handbook on Hyperbaric Medicine, Springer, Berlin, 239-261.
http://dx.doi.org/10.1007/1-4020-4448-8_14
[39] Kim, C.H., Choi, H., Chun, Y.S., Kim, G.T., Park, J.W. and Kim, M.S. (2001) Hyperbaric oxygenation pretreatment induces catalase and reduces infarct size in ischemic rat myocardium. Pflügers Archiv: European Journal of Physiology, 442, 519-525.
[40] Kim, S., Yukishita, T., Lee, K., Yokota, S., Nakata, K., Suzuki, D. and Kobayashi, H. (2011) The effect of mildpressure hyperbaric therapy (Oasis O2) on fatigue and oxidative stress. Health, 3, 432-436.
http://dx.doi.org/10.4236/health.2011.37071
[41] Bennett, M.H., Lehm, J.P. and Jepson, N. (2011) Hyperbaric oxygen therapy for acute coronary syndrome. Cochrane Database of Systematic Reviews, 8, CD004818.

  
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