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Zoon’s balanitis with mucinous metaplasia: A case report and review of literature

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DOI: 10.4236/ojcd.2013.32008    4,288 Downloads   6,128 Views   Citations


Mucinous metaplasia of the squamous epithelium of the glans penis is very rarely seen in the setting of Zoon’s balanitis. We report a case of 40 year old male with a past medical history of paroxysmal nocturnal hemoglobinuria, status-post allogeneic hematopoietic cell transplantation from an HLA-matched sibling 6 years prior to evaluation, complicated by oral and cutaneous chronic graft-versus-host disease. Mucinous metaplasia was confirmed by PAS and Mucin stains, and plasmacytosis was confirmed by immunohistochemistry for CD138 and MUM1 markers. Kappa and Lambda immunostains revealed a polyclonal pattern. The etiology of zoon’s balanitis as well as the significance of mucinous metaplasia in these setting are unclear and need to be further investigated.

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Lai, J. , Cowen, E. , Stern, J. , Ballester, L. , Chu, E. , Chirinos, R. , Childs, R. and Lee, C. (2013) Zoon’s balanitis with mucinous metaplasia: A case report and review of literature. Open Journal of Clinical Diagnostics, 3, 33-36. doi: 10.4236/ojcd.2013.32008.


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