[1]
|
Esteller, M. (2011) Non-coding RNAs in human disease. Nature Reviews. Genetics, 12, 861-874.
doi:10.10398/nrg3074
|
[2]
|
Knowling, S. and Morris, K.V. (2011) Non-coding RNA and antisense RNA. Nature’s trash or treasure? Biochimie, 93, 1922-1927. doi:10.1016/j.biochi.2011.07.031
|
[3]
|
Lee, J.T. (2012) Epigenetic regulation by long non-coding RNAs. Science, 338, 1435-1439.
doi:10.1126/science.1231776
|
[4]
|
Rougeulle, C. and Heard, E. (2002) Antisense RNA in imprinting: spreading silence through Air. Trends in Genetics, 18, 434-437.
doi:10.1016/S0168-9525(02)0274-X
|
[5]
|
Sleutels, F., Zwart, R. and Barlow, D.P. (2002) The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature, 415, 810-813.
doi:10.1038/415810a
|
[6]
|
Mitsuya, K., Meguro, M., Lee, M.P., Katoh, M., Schulz, T.C., Kugoh, H., Yoshida, M.A., Niikawa, N., Feinberg, A.P. and Oshimura, M. (1999) LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids. Human Molecular Genetics, 8, 1209-1217. doi:10.1093/hmg/8.7.1209
|
[7]
|
Lee, M.P., DeBaun, M.R., Mitsuya, K., Galonek, H.L., Brandenburg, S., Oshimura, M. and Feinberg, A.P. (1999) Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting. Proceedings of the National Academy of Sciences of the USA, 96, 52035208. doi:10.1073/pnas.96.9.5203
|
[8]
|
Du, M., Zhou, W., Beatty, L.G., Weksberg, R. and Sadowski, P.D. (2004) The KCNQ1OT1 promoter, a key regulator of genomic imprinting in human chromosome 11p15.5. Genomics, 84, 288-300.
doi:10.1016/j.ygeno.2004.03.008
|
[9]
|
Pandey, R.R., Ceribelli, M., Singh, P.B., Ericsson, J., Mantovani, R. and Kanduri, C. (2004) NF-Y regulates the antisense promoter, bidirectional silencing, and differential epigenetic marks of the Kcnq1 imprinting control region. Journal of Biological Chemistry, 279, 52685-52693.
doi:10.1074/jbc.M408084200
|
[10]
|
Thakur, N., Tiwari, V.K., Thomassin, H., Pandey, R.R., Kanduri, M., G?nd?r, A., Grange, T., Ohlsson, R. and Kanduri, C. (2004) An antisense RNA regulates the bidirectional silencing property of the Kcnq1 imprinting control region. Molecular and Cellular Biology, 24, 78557862. doi:10.1128/MCB.24.18.7855-7862.2004
|
[11]
|
Bernard, D., Prasanth, K.V., Tripathi, V., Colasse, S., Nakamura, T., Xuan, Z., Zhang, M.Q., Sedel, F., Jourdren, L., Coulpier, F., et al. (2010) A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO Journal, 29, 3082-3093.
doi:10.1038/emboj.2010.199
|
[12]
|
Tripathi, V., Ellis, J.D., Shen, Z., Song, D.Y., Pan, Q., Watt, A.T., Freier, S.M., Bennett, C.F., Sharma, A., Bubulya, P.A., et al. (2010) The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular Cell, 39, 925-938. doi:10.1016/j.molcel.2010.08.011
|
[13]
|
Loewer, S., Cabili, M.N., Guttman, M., Loh, Y.-H., Thomas, K., Park, I.H., Garber, M., Curran, M., Onder, T., Agarwal, S., et al. (2010) Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nature Genetics, 42, 1113-1117.
doi:10.1038/ng.710
|
[14]
|
Dinger, M.E., Amaral, P.P., Mercer, T.R., Pang, K.C., Bruce, S.J., Gardiner, B.B., Askarian-Amiri, M.E., Ru, K., Soldà, G., Simons, C., et al. (2008) Long non-coding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Research, 18, 1433-1445.
doi:10.1101/gr.078378.108
|
[15]
|
Rinn, J.L., Kertesz, M., Wang, J.K., Squazzo, S.L., Xu, X., Brugmann, S.A., Goodnough, L.H., Helms, J.A., Farnham, P.J., Segal, E., et al. (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by non-coding RNAs. Cell, 129, 1311-1323.
doi:10.1016/j.cell.2007.05.022
|
[16]
|
Tano, K. and Akimitsu, N. (2012) Long non-coding RNAs in cancer progression. Frontiers in Genetics, 3, 219. doi:10.3389/fgene.2012.00219
|
[17]
|
Shore, A.N., Herschkowitz, J.I. and Rosen, J.M. (2012) Non-coding RNAs Involved in Mammary Gland Development and Tumorigenesis: There’s a Long Way to Go. Journal of Mammary Gland Biology and Neoplasia, 17, 43-58. doi:10.1007/s10911-012-9247-3
|
[18]
|
Gupta, R.A., Shah, N., Wang, K.C., Kim, J., Horlings, H.M., Wong, D.J., Tsai, M.-C., Hung, T., Argani, P., Rinn, J.L., et al. (2010) Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature, 464, 1071-1076. doi:10.1038/nature08975
|
[19]
|
Cai, X. and Cullen, B.R. (2007) The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA, 13, 313-316. doi:10.1261/rna.351707
|
[20]
|
Tsang, W.P., Ng, E.K.O., Ng, S.S.M., Jin, H., Yu, J., Sung, J.J.Y. and Kwok, T.T. (2010) Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis, 31, 350-358.
doi:10.1093/carcin/bgp181
|
[21]
|
Keniry, A., Oxley, D., Monnier, P., Kyba, M., Dandolo, L., Smits, G. and Reik, W. (2012) The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and IGF1r. Nature Cell Biology, 14, 659-665.
|
[22]
|
Leighton, P.A., Ingram, R.S., Eggenschwiler, J., Efstratiadis, A. and Tilghman, S.M. (1995) Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature, 375, 34-39. doi:10.1038/375034a0
|
[23]
|
Ripoche, M.A., Kress, C., Poirier, F. and Dandolo, L. (1997) Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes and Development, 11, 1596-1604.
doi:10.1101/gad.11.12.1596
|
[24]
|
DeChiara, T.M., Robertson, E.J. and Efstratiadis, A. (1991) Parental imprinting of the mouse insulin-like growth factor II gene. Cell, 64, 849-859.
doi:10.1016/0092-8674(91)90513-X
|
[25]
|
Bartolomei, M.S., Webber, A.L., Brunkow, M.E. and Tilghman, S.M. (1993) Epigenetic mechanisms underlying the imprinting of the mouse H19 gene. Genes and Development, 7, 1663-1673. doi:10.1101/gad.7.9.1663
|
[26]
|
Ferguson-Smith, A.C., Sasaki, H., Cattanach, B.M. and Surani, M.A. (1993) Parental-origin-specific epigenetic modification of the mouse H19 gene. Nature, 362, 751755. doi:10.1038/362751a0
|
[27]
|
Grandjean, V., O’Neill, L., Sado, T., Turner, B. and Ferguson-Smith, A. (2001) Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted IGF2-H19 domain. FEBS Letters, 488, 165-169. doi:10.1016/S0014-5793(00)02349-8
|
[28]
|
Sasaki, H., Jones, P.A., Chaillet, J.R., Ferguson-Smith, A.C., Barton, S.C., Reik, W. and Surani, M.A. (1992) Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (IGF2) gene. Genes and Development, 6, 18431856. doi:10.1101/gad.6.10.1843
|
[29]
|
Feil, R., Walter, J., Allen, N.D. and Reik, W. (1994) Developmental control of allelic methylation in the imprinted mouse IGF2 and H19 genes. Development, 120, 2933-2943.
|
[30]
|
Murrell, A., Heeson, S., Bowden, L., Constancia, M., Dean, W., Kelsey, G. and Reik, W. (2001) An intragenic methylated region in the imprinted IGF2 gene augments transcription. EMBO Reports, 2, 1101-1106.
doi:10.1093/embo-reports/kve248
|
[31]
|
Constancia, M., Dean, W., Lopes, S., Moore, T., Kelsey, G. and Reik, W. (2000) Deletion of a silencer element in IGF2 results in loss of imprinting independent of H19. Nature Genetics, 26, 203-206. doi:10.1038/79930
|
[32]
|
Tremblay, K.D., Duran, K.L. and Bartolomei, M.S. (1997) A 5’ 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Molecular and Cellular Biology, 17, 43224329.
|
[33]
|
Drewell, R.A., Arney, K.L., Arima, T., Barton, S.C., Brenton, J.D. and Surani, M.A. (2002a) Novel conserved elements upstream of the H19 gene are transcribed and act as mesodermal enhancers. Development, 129, 12051213.
|
[34]
|
Takai, D., Gonzales, F.A., Tsai, Y.C., Thayer, M.J. and Jones, P.A. (2001) Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. Human Molecular Genetics, 10, 2619-2626.
doi:10.1093/hmg/10.23.2619
|
[35]
|
Hark, A.T., Schoenherr, C.J., Katz, D.J., Ingram, R.S., Levorse, J.M. and Tilghman, S.M. (2000) CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/IGF2 locus. Nature, 405, 486-489.
doi:10.1038/35013106
|
[36]
|
Srivastava, M., Hsieh, S., Grinberg, A., Williams-Simons, L., Huang, S.P. and Pfeifer, K. (2000) H19 and IGF2 monoallelic expression is regulated in two distinct ways by a shared cis-acting regulatory region upstream of H19. Genes and Development, 14, 1186-1195.
|
[37]
|
Murrell, A., Heeson, S. and Reik, W. (2004) Interaction between differentially methylated regions partitions the imprinted genes IGF2 and H19 into parent-specific chromatin loops. Nature Genetics, 36, 889-893.
|
[38]
|
Kurukuti, S., Tiwari, V.K., Tavoosidana, G., Pugacheva, E., Murrell, A., Zhao, Z., Lobanenkov, V., Reik, W. and Ohlsson, R. (2006) CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Proceedings of the National Academy of Sciences of the USA, 103, 10684-10689.
doi:10.1073/pnas.0600326103
|
[39]
|
Dekker, J., Rippe, K., Dekker, M. and Kleckner, N. (2002) Capturing chromosome conformation. Science, 295, 13061311. doi:10.1126/science.1067799
|
[40]
|
Taylor, E.R., Seleiro, E.A. and Brickell, P.M. (1991) Identification of antisense transcripts of the chicken insulin-like growth factor-II gene. Journal of Molecular Endocrinology, 7, 145-154. doi:10.1677/jme.0.0070145
|
[41]
|
Moore, T., Constancia, M., Zubair, M., Bailleul, B., Feil, R., Sasaki, H. and Reik, W. (1997) Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse IGF2. Proceedings of the National Academy of Sciences USA, 94, 12509-12514.
doi:10.1073/pnas.94.23.12509
|
[42]
|
Okutsu, T., Kuroiwa, Y., Kagitani, F., Kai, M., Aisaka, K., Tsutsumi, O., Kaneko, Y., Yokomori, K., Surani, M.A., Kohda, T., et al. (2000) Expression and imprinting status of human PEG8/IGF2as, a paternally expressed antisense transcript from the IGF2 locus, in Wilms’ tumors. Journal of Biochemistry, 127, 475-483.
doi:10.1093/oxfordjournals.jbchem.a022630
|
[43]
|
Duart-Garcia, C. and Braunschweig, M.H. (2013) The IGF2as transcript is exported into cytoplasm and associated with polysomes. Biochemical Genetics, 51, 119-130.
doi:10.1007/s10528-012-9547-8
|
[44]
|
Berteaux, N., Aptel, N., Cathala, G., Genton, C., Coll, J., Daccache, A., Spruyt, N., Hondermarck, H., Dugimont, T., Curgy, J.-J., et al. (2008) A novel H19 antisense RNA overexpressed in breast cancer contributes to paternal IGF2 expression. Molecular and Cellular Biology, 28, 6731-6745. doi:10.1128/MCB.02103-07
|
[45]
|
Tran, V.G., Court, F., Duputié, A., Antoine, E., Aptel, N., Milligan, L., Carbonell, F., Lelay-Taha, M.-N., Piette, J., Weber, M., et al. (2012) H19 antisense RNA can up-regulate IGF2 transcription by activation of a novel promoter in mouse myoblasts. PLoS ONE, 7, e37923.
doi:10.1371/journal.pone.0037923
|
[46]
|
Onyango, P. and Feinberg, A.P. (2011) A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript. Proceedings of the National Academy of Sciences of the USA, 108, 16759-16764.
doi:10.1073/pnas.1110904108
|
[47]
|
Court, F., Baniol, M., Hagege, H., Petit, J.S., Lelay-Taha, M.-N., Carbonell, F., Weber, M., Cathala, G. and Forne, T. (2011) Long-range chromatin interactions at the mouse IGF2/H19 locus reveal a novel paternally expressed long non-coding RNA. Nucleic Acids Research, 39, 5893-5906.
doi:10.1093/nar/gkr209
|
[48]
|
Pachnis, V., Belayew, A. and Tilghman, S.M. (1984) Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes. Proceedings of the National Academy of Sciences of the USA, 81, 5523-5527.
doi:10.1073/pnas.81.17.5523
|
[49]
|
Pachnis, V., Brannan, C.I. and Tilghman, S.M. (1988) The structure and expression of a novel gene activated in early mouse embryogenesis. The EMBO Journal, 7, 673681.
|
[50]
|
Zhang, Y. and Tycko, B. (1992) Monoallelic expression of the human H19 gene. Nature Genetics, 1, 40-44.
doi:10.1038/ng0492-40
|
[51]
|
Joubel, A., Curgy, J.J., Pelczar, H., Begue, A., Lagrou, C., Stehelin, D. and Coll, J. (1996) The 5’ part of the human H19 RNA contains cis-acting elements hampering its translatability. Cellular and Molecular Biology, 42, 11591172.
|
[52]
|
Brannan, C.I., Dees, E.C., Ingram, R.S. and Tilghman, S.M. (1990) The product of the H19 gene may function as an RNA. Molecular and Cellular Biology, 10, 28-36.
|
[53]
|
Yang, J.-S. and Lai, E.C. (2011) Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Molecular Cell, 43, 892-903.
doi:10.1016/j.molcel.2011.07.024
|
[54]
|
Li, Y.M., Franklin, G., Cui, H.M., Svensson, K., He, X.B., Adam, G., Ohlsson, R. and Pfeifer, S. (1998) The H19 transcript is associated with polysomes and may regulate IGF2 expression intrans. Journal of Biological Chemistry, 273, 28247-28252. doi:10.1074/jbc.273.43.28247
|
[55]
|
Wilkin, F., Paquette, J., Ledru, E., Hamelin, C., Pollak, M., Deal, C.L. and Mamelin, C. (2000) H19 sense and antisense transgenes modify insulin-like growth factor-II mRNA levels. European Journal of Biochemistry, 267, 4020-4027. doi:10.1046/j.1432-1327.2000.01438.x
|
[56]
|
Lottin, S., Adriaenssens, E., Dupressoir, T., Berteaux, N., Montpellier, C., Coll, J., Dugimont, T. and Curgy, J.J. (2002) Overexpression of an ectopic H19 gene enhances the tumorigenic properties of breast cancer cells. Carcinogenesis, 23, 1885-1895.
doi:10.1093/carcin/23.11.1885
|
[57]
|
Poirier, F., Chan, C.T., Timmons, P.M., Robertson, E.J., Evans, M.J. and Rigby, P.W. (1991) The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development, 113, 1105-1114.
|
[58]
|
Lustig, O., Ariel, I., Ilan, J., Lev-Lehman, E., De-Groot, N. and Hochberg, A. (1994) Expression of the imprinted gene H19 in the human fetus. Molecular Reproduction and Development, 38, 239-246.
doi:10.1002/mrd.1080380302
|
[59]
|
Ohlsson, R., Hedborg, F., Holmgren, L., Walsh, C. and Ekström, T.J. (1994) Overlapping patterns of IGF2 and H19 expression during human development: Biallelic IGF2 expression correlates with a lack of H19 expression. Development, 120, 361-368.
|
[60]
|
Hemberger, M., Redies, C., Krause, R., Oswald, J., Walter, J. and Fundele, R.H. (1998) H19 and IGF2 are expressed and differentially imprinted in neuroecto-dermderived cells in the mouse brain. Development Genes and Evolution, 208, 393-402.doi:10.1007/s004270050195
|
[61]
|
Douc-Rasy, S., Coll, J., Barrois, M., Joubel, A., Prost, S., Dozier, C., Stéhelin, D. and Riou, G. (1993) Expression of the human fetal BAC/H19 gene in invasive cancer. International Journal of Oncology, 2, 753-758.
|
[62]
|
Okamoto, K., Morison, I.M., Taniguchi, T. and Reeve, A.E. (1997) Epigenetic changes at the insulin-like growth factor II/H19 locus in developing kidney is an early event in Wilms tumorigenesis. Proceedings of the National Academy of Sciences of the USA, 94, 5367-5371.
doi:10.1073/pnas.94.10.5367
|
[63]
|
Steenman, M.J., Rainier, S., Dobry, C.J., Grundy, P., Horon, I.L. and Feinberg, A.P. (1994) Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms’ tumour. Nature Genetics, 7, 433-439. doi:10.1038/ng0794-433
|
[64]
|
Dugimont, T., Curgy, J.J., Wernert, N., Delobelle, A., Raes, M.B., Joubel, A., Stehelin, D. and Coll, J. (1995) The H19 gene is expressed within both epithelial and stromal components of human invasive adenocarcinomas. Biology of the Cell, 85, 117-124.
doi:10.1016/0248-4900(96)85272-5
|
[65]
|
Adriaenssens, E., Lottin, S., Dugimont, T., Fauquette, W., Coll, J., Dupouy, J.P., Boilly, B. and Curgy, J.J. (1999) Steroid hormones modulate H19 gene expression in both mammary gland and uterus. Oncogene, 18, 4460-4473.
doi:10.1038/sj.onc.1202819
|
[66]
|
Ariel, I., Ayesh, S., Perlman, E.J., Pizov, G., Tanos, V., Schneider, T., Erdmann, V.A., Podeh, D., Komitowski, D., Quasem, A.S., et al. (1997) The product of the imprinted H19 gene is an oncofetal RNA. Molecular Pathology, 50, 34-44. doi:10.1136/mp.50.1.34
|
[67]
|
Ariel, I., Lustig, O., Schneider, T., Pizov, G., Sappir, M., De-Groot, N. and Hochberg, A. (1995) The imprinted H19 gene as a tumor marker in bladder carcinoma. Urology, 45, 335-338. doi:10.1016/0090-4295(95)80030-1
|
[68]
|
Elkin, M., Shevelev, A., Schulze, E., Tykocinsky, M., Cooper, M., Ariel, I., Pode, D., Kopf, E., De Groot, N. and Hochberg, A. (1995). The expression of the imprinted H19 and IGF2 genes in human bladder carcinoma. FEBS Letters, 374, 57-61.
doi:10.1016/0014-5793(95)01074-O
|
[69]
|
Yang, F., Bi, J., Xue, X., Zheng, L., Zhi, K., Hua, J. and Fang, G. (2012) Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells. FEBS Journal, 279, 3159-3165.
doi:10.1111/j.1742-4658.2012.08694.x
|
[70]
|
Dugimont, T., Montpellier, C., Adriaenssens, E., Lottin, S., Dumont, L., Iotsova, V., Lagrou, C., Stéhelin, D., Coll, J. and Curgy, J.J. (1998) The H19 TATA-less promoter is efficiently repressed by wild-type tumor suppressor gene product p53. Oncogene, 16, 2395-2401.
doi:10.1038/sj.onc.1201742
|
[71]
|
Adriaenssens, E., Dumont, L., Lottin, S., Bolle, D., Leprêtre, A., Delobelle, A., Bouali, F., Dugimont, T., Coll, J. and Curgy, J.J. (1998) H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression. American Journal of Pathology, 153, 1597-1607. doi:10.1016/S0002-9440(10)65748-3
|
[72]
|
Matouk, I.J., DeGroot, N., Mezan, S., Ayesh, S., Abu-lail, R., Hochberg, A. and Galun, E. (2007) The H19 noncoding RNA is essential for human tumor growth. PLoS ONE, 2, e845. doi:10.1371/journal.pone.0000845
|
[73]
|
Matouk, I.J., Mezan, S., Mizrahi, A., Ohana, P., Abu-Lail, R., Fellig, Y., Degroot, N., Galun, E. and Hochberg, A. (2010) The oncofetal H19 RNA connection: Hypoxia, p53 and cancer. Biochimica et Biophysica Acta, 1803, 443-451.
|
[74]
|
Ravi, R., Mookerjee, B., Bhujwalla, Z.M., Sutter, C.H., Artemov, D., Zeng, Q., Dillehay, L.E., Madan, A., Semenza, G.L. and Bedi, A. (2000) Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes and Development, 14, 34-44.
|
[75]
|
Berteaux, N., Lottin, S., Monté, D., Pinte, S., Quatannens, B., Coll, J., Hondermarck, H., Curgy, J.-J., Dugimont, T. and Adriaenssens, E. (2005) H19 mRNA-like non-coding RNA promotes breast cancer cell proliferation through positive control by E2F1. Journal of Biological Chemistry, 280, 29625-29636. doi:10.1074/jbc.M504033200
|