Polymeric biomaterial hydrogels. I. Behavior of some ionotropic cross-linked metal-alginate hydrogels especially copper-alginate membranes in some organic solvents and buffer solutions

Abstract

The change in rheological and mechanical properties for some ionotropic cross-linked metal-alginate hydrogel complexes in particularly copper-alginate membranes in the presence of some organic solvents (benzene, toluene, xylene, carbon tetrachloride, ace-tone, chloroform, dichloroethane, isobutyl alcohol and ethyl alcohol) or buffer solutions (acetates, borates and universal buffers) have been investigated. The experimental results showed a remarkable tendency of the studied hydrogels for shrinking in polar solvents, whereas no influence was observed for the hydrogels in non-polar solvents. On the other hand, the gels were found to swell or shrink in the buffer solutions depending on the pH of the buffer used. The swelling extent for hydrogel spheres was found to decrease in the order Cu > Ba ≈ Ca > Zn > Pb-alginates in universal buffers of pH = 5.33. The factors affected this behavior have been examined and discussed.

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Hassan, R. , Tirkistani, F. , Zaafarany, I. , Fawzy, A. , Khairy, M. and Iqbal, S. (2012) Polymeric biomaterial hydrogels. I. Behavior of some ionotropic cross-linked metal-alginate hydrogels especially copper-alginate membranes in some organic solvents and buffer solutions. Advances in Bioscience and Biotechnology, 3, 845-854. doi: 10.4236/abb.2012.37105.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Ozeroglu, C. and Birdol, A. (2009) Swelling properties of acrylamide-N,N-methylene bis (acrylamide) hydrogel synthesized by using meso-2,3-dimercaptosuccinic acidcerium (IV) redox couple. Express Polymer Letter, 3, 168- 176. doi:10.3144/expresspolymlett.2009.22
[2] Saha, N., Saarai, A., Ray, N., Kilano, T. and Shasaha, P. (2011) Polymeric biomaterial based hydrogels for biomedical application. Journal of biomaterial nanotechnology, 2, 85-90.
[3] Torres, L.G., Sanchezdela-Vega, A., Beltran, N.A. and Jimenez, B.E. (1998) Production and characterization of a Ca-alginate biocatalyst for removal of phenol and chlorophenols from wastewaters. Process Biochemistry, 33, 625-634. doi:10.1016/S0032-9592(98)00026-0
[4] Torres, L.G., Velasquez, A. and Brito-Arias, M.A. (2011) Ca-alginate spheres behavior in presence of some solvents and water-solvent mixtures. Advances in Bioscience and Biotechnology, 2, 8-12. doi:10.4236/abb.2011.21002
[5] Schweiger, R. (1962) Acetylation of alginic acid. II. Reaction of algin acetates with calcium and other divalent ions. Journal of Organic Chemistry, 27, 1789-1791. doi:10.1021/jo01052a073
[6] Haugh, A. and Smidsrod, O. (1965) The effect of divalent metals on the properties of alginate solution. I & II Calcium ions. Acta Chemica Scandinavica, 19, 341. doi:10.3891/acta.chem.scand.19-0341
[7] Thiele, H. and Awad, A. (1966) Ions and their biological effects. Investigation on ionotropic gels. Biotechnology, 3, 63-75.
[8] Awad, A., El-Cheikh, F. and Hassan, R.M. (1979) Kinetics of solgel transformation especially ionotropic gels. Revue Roumaine de Chimie, 2, 8-12.
[9] Hassan, R.M., Wahdan, M.H. and Hassan, A. (1988) Kinetics and mechanism of solgel transformation on polyelectrolytes of nickel alginate ionotropic membranes. European Polymer Journal, 24, 281-283. doi:10.1016/0014-3057(88)90223-6
[10] Hassan, R.M., El-Shatoury, S.A., Mousa, M.A. and Hassan, A. (1988) Kinetics and mechanism of solgel transformation for polyelectrolytes of capillary copper alginate ionotropic membranes. European Polymer Journal, 24, 1173-1175. doi:10.1016/0014-3057(88)90106-1
[11] Hassan, R.M., Summan, A.M., Hassan, M.K. and El-Shatoury, S.A. (1989) Kinetics and mechanism of solgel transformation on polyelectrolytes of some transition metal ions especially cobalt alginate ionotropic membranes. European Polymer Journal, 25, 1209-1212. doi:10.1016/0014-3057(89)90083-9
[12] Khairou, K.S., El-Gethami, W.M. and Hassan, R.M. (2002) Kineticsand mechanism of solgel transformation between sodium alginate polyelectrolyte and some heavy divalent metal ions with formation of capillary polymembranes ionotropic gels. Journal of Membrane Science, 209, 445-465. doi:10.1016/S0376-7388(02)00353-8
[13] Hassan, R.M., Makhlouf, M.Th. and El-Shatoury, S.A. (1992) Alginate polyelectrolyte ionotropic gels. IX. Diffusion control effects on the relaxation time of solgel transformation of divalent metal alginate ionotropic gel complexes. Colloid and Polymer Science, 12, 1237-1242. doi:10.1007/BF01095065
[14] Khairou, K.S., Al-Gethami, W.M. and Hassan, R.M. (2003) Diffusion controls influence on relaxation time and velocity of acceleration of solgel transformation for cross-linked metal alginate ionotropic gel complexes. Bulletin of Polish Academic of Sciences, 51, 209-220.
[15] Hassan, R.M. (1989) Influence of frequency on electrical properties of acid and trivalent metal alginate ionotropic gels. A correlation between strength of chelation and stability of polye1ectrolyre gels high perform. Polymer, 1, 275-284.
[16] Hassan, R.M., Makhlouf, M.Th. and Summan, A.M. (1989) Influence of frequency on specific conductance of polyelectrolyte gels with special correlation between strength of chelation and stability of divalent metal alginate ionotropic gels. European Polymer Journal, 25, 993-996. doi:10.1016/0014-3057(89)90126-2
[17] Hassan, R.M. (1991) Alginate polyelectrolyte ionotropic gels. III. Kinetics of exchange of chelated divalent transition metal ions especially cobalt (II) and copper (II) by hydrogen ions in capillary ionotropic metal alginate polymembrane gels. Journal of Material Science, 26, 5806- 5810. doi:10.1007/BF01130118
[18] Hassan, R.M. (1991) Alginate polyelectrolyte ionotropic gels. Part II: Kinetics and mechanism of exchange of chelated nickel (II) by hydrogen ions in capillary ionotropic nickel-alginate polymembrane gel complex. Journal of Material Science, 28, 384-388. doi:10.1007/BF00357813
[19] Said, A.A. and Hassan, R.M. (1993) Thermal decomposition of some divalent metal alginate gel compounds. Jour- nal of Polymer Degradation Stability, 39, 393-397. doi:10.1016/0141-3910(93)90015-B
[20] Khairou, K.S. (2002) Kinetics and mechanism of the non-isothermal decomposition of some divalent cross- linked metal alginate ionotropic gels. Journal of Thermal and Calorimetry, 69, 583-588. doi:10.1023/A:1019920108863
[21] Said, A.A., Abd El-Wahab, M.M. and Hassan, R.M. (1994) Thermal and electrical studies on some metal alginate compounds. Thermochimica Acta, 233, 13-24. doi:10.1016/S0040-6031(99)80002-1
[22] El-Gahami, M.A., Khairou, K.S. and Hassan, R.M. (2003) Thermal decomposition of Sn(II), Pb(II), Cd(II) and Hg(II) cross-linked metal-alginate complexes. Bulletin of Polish Academic Science, 51, 105-113.
[23] Khairou, K.S. and Hassan, R.M. (2002) Temperature-dependence of electrical conductivity for cross-linked mono- and divalent metal alginate complexes. High Performance Polymer, 14, 93-99. doi:10.1177/0954008302014001092
[24] Zaafarany, I.A., Khairou, K.S. and Hassan, R.M. (2010) Physicochemical studies on some cross-linked trivalent metal-alginate complexes especially the electrical conductivity and chemical equilibrium related to the coordination geometry. High Performance Polymer, 22, 69-81. doi:10.1177/0954008308095287
[25] Zaafarany, I.A., Khairou, K.S., Hassan, R.M. and Ikeda, Y. (2009) Physicochemical studies on cross-linked thorium(IV)-alginate complex especially the electrical conductivity and chemical equilibrium related to the coordination geometry. Arabian Saudi Journal, 2, 1-10.
[26] John, A.D. (1979) Langes handbook of chemistry. 11th Edition, McGraw-Hill Co., New York.
[27] Hassan, R.M., El-Shatoury, S.A. and Makhlouf, M.Th. (1992) Alginate polyelectrolyte ionotropic gels. XII. Chromatographic separation of metal ions in mixture solutions. High Performance Polymer, 4, 49-54. doi:10.1088/0954-0083/4/1/006
[28] Hassan, R.M., Awad, A. and Hassan, A. (1991) Separation of metal alginate ionotropic gels to polymembranes with especial evidence on the position of chelation in copper alginate complex. Journal of Polymer Science A, 29, 1645-1648. doi:10.1002/pola.1991.080291115
[29] Hellferich, F. (1962) Ion Exchange. McGraw-Hill, New York.
[30] Rees, D.A. (1972) Polysaccharide gels, a molecular view. Chemical Industry, 630-636.
[31] Hassan, R.M. (1993) Alginate polyelectrolyte ionotropic gels. XIII. Geometrical aspects for chelation in metal alginate complexes related to their physico-chemical properties. Polymer International, 31, 81-86. doi:10.1002/pi.4990310112
[32] Thiele, H. and Hallich, K.H. (1957) Capillary structure in ionotropic gels. Kolloid-Zeitschrift, 151, 1-12. doi:10.1007/BF01502248
[33] Obolonkova, E.M., Belavtseva, E.M., Braudo, E.E. and Tolstoguzov, V.B. (1974) Formation and structure of ionotropic gels. II. Electron microscopic investigation of anisotropic calcium-alginate gels. Colloid Polymer Science, 252, 526-529. doi:10.1007/BF01558145
[34] Tolstoguzov, V.B. (1974) I. Ionotropic gels of a laminated structure. Colloid and Polymer Science, 253, 109- 113. doi:10.1007/BF01775674

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