Treatment of Wrinkles and Acne Scars Using the TriFractional, a Novel Fractional Radiofrequency Technology—Clinical and Histological Results

Alex Levenberg, Andrea Gat, Marie Christine Branchet, Sylvie Boisnic

Dermatopathology Unit, Sourasky Medical Center, Tel Aviv, Israel.
GREDECO Research Group, Paris, France.
Physicians Center, Plastic Surgery Department, Tel Aviv, Israel.

DOI: 10.4236/jcdsa.2012.23023                

Abstract

Introduction: The need for cosmetic facial enhancement procedures with minimal down time and low risk has led to the development of methods for non-surgical skin rejuvenation. Various ablative lasers were developed, which remove the full skin surface in a controlled manner. However, the prolonged recovery and the significant risks prompted the development of fractional lasers which ablate the skin in a fractional manner, leaving untreated areas to improve healing process. In the past few years, fractional radiofrequency (RF) systems have been introduced that enable controlled skin resurfacing accompanied with dermal collagen remodeling. The new TriFractional technology from Pollogen? is designed to enable skin resurfacing and treatment of wrinkles using RF energy. The objective of the current research was to evaluate the safety and effectiveness of the novel TriFractional technology using the TriFractional applicator (A3F) for micro-ablative skin resurfacing and the treatment of wrinkles and acne scars. Methods: Healthy volunteers consented to undergo TriFractional treatments for various aesthetic indications. In addition, in-vivo and ex-vivo histologycal results showing immediate and long term effects of the TriFractional technology were obtained. A portion of the subjects underwent the complete TriLipo Med^TM Procedure which includes 2 TriFractional treatments spaced one month apart, with 2 TriLipo RF + Dynamic Muscle Activation (DMA) face treatments two weeks after each TriFractional treatment. Results: Subjects experienced an improvement of wrinkles, skin texture and acne scars along with facial contouring. No significant adverse effects were detected post-treatment. Histology findings demonstrated immediate and long term TriFractional effects on both epidermal and dermal skin layers. Conclusions: TriFractional is a promising technology for skin resurfacing, treatment of wrinkles and improvement of additional aesthetic indications such as acne scars. The TriLipo MED^TM procedure is a unique combination approach for total facial rejuvenation and contouring.

Keywords

Radiofrequency; Trifractional; Wrinkles; Acne Scars; Collagen

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	C. A. Nanni and T. S. Alster, “Complications of CO2 Laser Resurfacing: An Evaluation of 500 Patients,” Dermatologic Surgery, Vol. 24, No. 3, 1998, pp. 315-320.
[2]	E. L. Tanzi and T. S. Alster, “Side Effects and Complications of Variable Pulsed Erbium: YAG Laser Skin Resurfacing: Extended Experience with 50 Patients,” Plastic and Reconstructive Surgery, Vol. 111, No. 4, 2003, pp. 1524-1529. doi:10.1097/01.PRS.0000049647.65948.50
[3]	D. Manstein, G. S. Herron, R. K. Sink, et al., “Fractional Photothermolysis: A New Concept for Cutaneous Remodeling Using Microscopic Patterns of Thermal Injury,” Lasers in Surgery and Medicine, Vol. 34, No. 5, 2004, pp. 426-438. doi:10.1002/lsm.20048
[4]	H. J. Laubach, Z. Tannous, R. R. Anderson and D. Manstein, “Skin Responses to Fractional Photothermolysis,” Lasers in Surgery and Medicine, Vol. 38, No. 2, 2006, pp. 142-149. doi:10.1002/lsm.20254
[5]	E. P. Tierney, R. F. Eisen and C. W. Hanke, “Fractionated CO2 Laser Skin Rejuvenation,” Dermatology and Therapy, Vol. 24, No. 1, 2011, pp. 41-53. doi:10.1111/j.1529-8019.2010.01377.x
[6]	H. Kaplan and A. Gat, “Clinical and Histopathological Results Following TriPollar Radiofrequency Skin Treatments,” Journal of Cosmetic and Laser Therapy, Vol. 11, No. 2, 2009, pp. 78-84.
[7]	S. Boisnic and M. C. Branchet, “Ex Vivo Human Skin Evaluation of Localized Fat Reduction and Anti-Aging Effect by TriPollar Radio Frequency Treatments,” Journal of Cosmetic and Laser Therapy, Vol. 12, No. 1, 2010, pp. 25-31. doi:10.3109/14764170903376232
[8]	A. Levenberg, “Clinical Experience with a TriPollar Radiofrequency System for Facial and Body Aesthetic Treatments,” European Journal of Dermatology, Vol. 20, No. 5, 2010, pp. 615-619.
[9]	G. Hruza, A. F. Taub, S. L. Collier and S. R. Mulholland, “Skin Rejuvenation and Wrinkle Reduction Using a Fractional Radiofrequency System,” Journal of Drugs in Dermatology, Vol. 8, No. 3, 2009, pp. 259-265.
[10]	L. Brightman, M. P. Goldman and A. F. Taub, “Sublative Rejuvenation: Experience with a New Fractional Radio-frequency System for Skin Rejuvenation and Repair,” Journal of Drugs in Dermatology, Vol. 8, No. 11, 2009, pp. 9-13.
[11]	N. S. Sadick, M. Sato, D. Palmisano, et al., “In Vivo Animal Histology and Clinical Evaluation of Multisource Fractional Radiofrequency Skin Resurfacing (FSR) Applicator,” Journal of Cosmetic and Laser Therapy, Vol. 13, No. 5, 2011, pp. 204-209.