Metastasis to Paranasal Sinuses as the First Presenting Sign of Renal Cell Carcinoma

Abstract

The clear cell carcinoma is a relatively rare tumor, represented approximately 85% by renal cell carcinoma (RCC), but has a characteristic of early metastatic, which sometimes spread to unusual places. Metastatic tumors in the paranasal sinuses are very rare. This case report a 65 years-old patient who presented sinusitis and epitaxis as a first sign of renal cell carcinoma with metastasis to the right maxillary sinus, which was opereted at Lagoa Hospital—RJ and strengthen the inclusion of this disease in the differential diagnosis of sinus disease. The renal cell carcinoma is a relatively rare tumor, representing approximately 3% of malignant tumors. About a third of patients with renal cell carcinoma have metastasis at diagnosis. The sinuses are a rare location of metastasis. The maxillary sinuses and the paranasal sinuses are most commonly affected by metastatic tumors to the sinuses region. The most frequent primary tumor to metastasis to paranasal sinuses is the renal cell carcinoma. This report highlights the rarity of the case and the importance in the differential diagnosis of sinus disease.

Share and Cite:

G. Bechara, J. Júnior, H. Gouveia and T. Souza, "Metastasis to Paranasal Sinuses as the First Presenting Sign of Renal Cell Carcinoma," Open Journal of Urology, Vol. 2 No. 1, 2012, pp. 28-31. doi: 10.4236/oju.2012.21006.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] A. J. Wein, L. R. Kavoussi, A. C. Novick, A. W. Partin and C. A. Partin, “Campbell-Walsh Urology,” Saunders: An Imprint of Elsevier, Philadelphia, 2007.
[2] B. T. Muros, J. R. S. Romero, J. G. B. Rodriguez and R. B. Parrilla, “Maxillary Sinus Metastasis of Renal Cell Carcinoma,” ACTAS Urologicas Espanolas, Vol. 30, No. 9, 2006, pp. 954-957. doi:10.4321/S0210-48062006000900015
[3] G. Fischetti, S. Cuzari, P. Leone, P. De Martino, M. Musy, S. Mariane, A. Fraioli and M. A. Valentini, “Immunotherapy in the Management of Metastatic Renal Carcinoma”, Minerva Urologica e Nefrologica, Vol. 54, No. 2, 2002, pp. 113-117.
[4] J. Avolius, D. Astorokos, C. Avlovich and P. Usso, “Resection of Metastatic Renal Cell Carcinoma,” Journal of Clinical Oncology, Vol. 16, No. 6, 1998, pp. 2261-2266.
[5] H. A. Koutnouyan, G. J. Rumore and J. M. Kahn, “Skull Metastasis from Renal Cell Carcinoma. Case Report and Literature Review,” Annals of Otology, Rhinology and Laryngology, Vol. 107, No. 7, 1998, pp. 598-602.
[6] C. S. Duque-Fisher, R. Casiano, A. Vélez-Hoyos and A. F. Londono-Bustamente, “Metastasis to the Sinonasal Re- gion,” Acta Otorrinolaringologica Espanola, Vol. 60, No. 6, 2009, pp. 428-431. doi:10.1016/j.otorri.2009.06.003
[7] J. M. Del Portal, F. Anaya, E. Solis, J. Segura, A. Robles and J. M. Castilla, “Transitional Vesical Cell Carcinoma Metastatizing to the Sphenoid Sinus,” Acta Otorrinolaringologica Espanola, Vol. 57, No. 2, 2006, pp. 118-120.
[8] A. Precher, M. Santis and D. Brors, “Renal Cell Carcinoma Presenting with Orbital Metastases,” Laryngorhinootologie, Vol. 80, 2001, pp. 583-594.
[9] B. Kaminski, J. Kobirorska-Nowak and S. Bien, “Distant Metastases to Nasal Cavities and Paranasal Sinuses, from the Organs outside the Head and Neck,” The Polish otolaryngology, Vol. 62, No. 4, 2008, pp. 422-425.
[10] F. L. Heldwein, B. Escudier, G. Smyth, C. A. Souto and G. Vallancien, “Metastatic Renal Cell Carcinoma Management,” International Journal of the Brazilian Society of Urology, Vol. 35, No. 3, 2009, pp. 256-270. doi:10.1590/S1677-55382009000300002
[11] J. B. Morvan, J. B. Veyrières, O. Mimouni, O. Cathelinaud, L. Allali and P. Verdalle, “Clear-Cell Renal Carcinoma Metastasis to the Base of the Tongue and Sphenoid Sinus: Two very Rare Atypical ENT Locations,” European Annals of Otorhinolaryngology, Head and Neck Diseases, Vol. 128, No. 2, 2011, pp. 91-94. doi:10.1016/j.anorl.2010.11.003
[12] L. Zini, U. Capitanio, P. Perrotte, C. J. Claudio, S. F. Shariat, P. Arjane, H. Widmer, F. Montorsi, J. J. Patard and P. I. Karakiewicz, “Population-Based Assessment of Survival after Cytoreductive Nephrectomy versus No Surgery in Patients with Metastatic Renal Cell Carcinoma,” Urology, Vol. 73, No. 2, 2009, pp. 342-346. doi:10.1016/j.urology.2008.09.022

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.