Author(s)

Indah Nur Pramesti, Yutaka Okada^*

Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan.

The Claisen rearrangement is a [3,3]-sigmatropic rearrangement which is an important method for new C-C bond formation in organic synthesis. This reaction is a typical thermal reaction that requires a high temperature and long reaction time. In this paper, the acceleration effects of the iron (III) chloride (FeCl₃) catalyst and microwave irradiation during the Claisen rearrangement reaction of allyloxyarene derivatives are reported. The FeCl₃ catalyst was able to initiate the reaction at low temperature and induced the subsequent cyclization reaction. The moderation of excellent yields was obtained in a short reaction time. The formation of complex ferric-arenes under microwave irradiation conditions to efficiently absorb the microwaves was expected and confirmed.

FeCl₃, Claisen Rearrangement, Allyloxyarenes, Microwave Irradiation Effect

Pramesti, I. and Okada, Y. (2017) Iron (III) Chloride Catalyzed Claisen Rearrangement Reaction of Allyloxyarenes under Microwave Conditions. Green and Sustainable Chemistry, 7, 234-245. doi: 10.4236/gsc.2017.73018.