Therapeutic Aspects of Chronic Bone Infections and Management Challenges - Open Journal of Orthopedics

OJO > Vol.4 No.2, February 2014

Open Journal of Orthopedics

Volume 4, Issue 2 (February 2014)

ISSN Print: 2164-3008 ISSN Online: 2164-3016

Google-based Impact Factor: 0.25 Citations h5-index & Ranking

Therapeutic Aspects of Chronic Bone Infections and Management Challenges ()

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DOI: 10.4236/ojo.2014.42004 4,832 Downloads 7,555 Views Citations

Author(s)

Charles Diémé, Lamine Sarr, Alioune Badara Guèye, Ndeye Fatou Coulibaly, André Sané, Abdoulaye Ndiaye, Seydina Sèye

Affiliation(s)

Department of Orthopaedic and Trauma Surgery, Aristide Le Dantec Teaching Hospital, Dakar, Sénégal.
Department of Orthopaedic and Trauma Surgery, Aristide Le Dantec Teaching Hospital, Dakar, Sénégal..

ABSTRACT

This study aims to investigate various aspects of the treatment of chronic bone infections and the challenges in their management. The characterization of treatment of 73 patients with chronic bone infection was reported. The four management challenges including consultation delay, immune depression, extreme variety of clinical manifestations and non-use of CT or MRI were discussed in this study. We conducted a retrospective study at Aristide Le Dantec Hospital on 90 cases of chronic bone infection in 73 patients. The mean duration of symptoms before consultation was 36 months. More than half of the patients had a productive fistula at the first consultation. Sickle cell anemia was found in 6 patients. Multiple lesions were found in 10 patients; and long bones were affected in 90% of cases. The bacterial culture was positive in 93.15%. Staphylococcus aureus was the most isolated germ (68.35%). Seventy-two out of seventy-three patients were operated on. The procedure depended on anatomical and radiological lesions. Surgical treatment was associated with antibiotherapy which was firstly probabilistic and secondarily adapted to the results of bacterial culture. A favorable trend was found in 41 patients (56.16%). 32 cases of adverse effects were noted (43.83%), and 27 patients had recurrence after a favorable outcome. Several complications and sequelae were observed demonstrating the tenacity of these chronic infections.

KEYWORDS

Chronic Bone Infection; Management; Challenges

Share and Cite:

C. Diémé, L. Sarr, A. Guèye, N. Coulibaly, A. Sané, A. Ndiaye and S. Sèye, "Therapeutic Aspects of Chronic Bone Infections and Management Challenges," Open Journal of Orthopedics, Vol. 4 No. 2, 2014, pp. 21-26. doi: 10.4236/ojo.2014.42004.

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