Advances in Bioscience and Biotechnology

Volume 1, Issue 5 (December 2010)

ISSN Print: 2156-8456   ISSN Online: 2156-8502

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Quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) in quetiapine fumarate by gas chromatogaraphy

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DOI: 10.4236/abb.2010.15049    6,044 Downloads   14,382 Views  Citations

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ABSTRACT

A simple and specific gas chromatographic method developed and validated for the determination of 2-(2-chloroethoxy) ethanol in Quetiapine Fumarate. The method is carried out with a flame ionization detector and DB-FFAP capillary column. The linearity was established over a range of 40-150 µg ml-1 and correlation coefficient is more than 0.999.

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Tiwari, P. , Yadav, R. , Sathe, P. and Gangrade, D. (2010) Quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) in quetiapine fumarate by gas chromatogaraphy. Advances in Bioscience and Biotechnology, 1, 367-371. doi: 10.4236/abb.2010.15049.

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