Quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) in quetiapine fumarate by gas chromatogaraphy ()
ABSTRACT
A simple and specific gas chromatographic method developed and validated for the determination of 2-(2-chloroethoxy) ethanol in Quetiapine Fumarate. The method is carried out with a flame ionization detector and DB-FFAP capillary column. The linearity was established over a range of 40-150 µg ml-1 and correlation coefficient is more than 0.999.
Share and Cite:
Tiwari, P. , Yadav, R. , Sathe, P. and Gangrade, D. (2010) Quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) in quetiapine fumarate by gas chromatogaraphy.
Advances in Bioscience and Biotechnology,
1, 367-371. doi:
10.4236/abb.2010.15049.