A holographic analysis of large scale structure in the universe provides an upper bound on the mass of supermassive black holes at the center of large scale structures with matter density varying as as a function of distance r from their center. The upper bound is consistent with two important test cases involving observations of the supermassive black hole with mass times the galactic mass in Sagittarius A^* near the center of our Milky Way and the 2 × 10⁹ solar mass black hole in the quasar ULAS J112001.48 + 064124.3 at redshift z = 7.085. It is also consistent with upper bounds on central black hole masses in globular clusters M15, M19 and M22 developed using the Jansky Very Large Array in New Mexico.