Advances in Nanoparticles

Volume 2, Issue 1 (February 2013)

ISSN Print: 2169-0510   ISSN Online: 2169-0529

Google-based Impact Factor: 2.25  Citations  

Studies on Dissolution Behaviour of Nanoparticulate Curcumin Formulation

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DOI: 10.4236/anp.2013.21010    12,670 Downloads   22,071 Views  Citations
Author(s)

ABSTRACT

Curcumin is the main biologically active phytochemical compound of turmeric that has been widely used by ancient cultures throughout Asia. However the dissolution rate limited absorption and pre-absorption degradation limits its use as a potential therapeutic. In this study an attempt has been made to overcome the above limitations by curcumin delivery through nanotechnology. Nanocurcumin solid dosage formulations were prepared and studied for its dissolution behaviour. Considerable improvement in the dissolution behavior was observed in the drug nanocrystal-loaded solid dosage forms. This is expected to enhance the bioavailability of poorly soluble medicinal herbs such as turmeric in the body.

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Ravichandran, R. (2013) Studies on Dissolution Behaviour of Nanoparticulate Curcumin Formulation. Advances in Nanoparticles, 2, 51-59. doi: 10.4236/anp.2013.21010.

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