Causes of Maternal Mortality According to Reports of Maternal Death Audits in the University Teaching Hospital Bogodogo ( UTH-B ) from January to December 2017

Objective: To study causes of maternal mortality according to reports of maternal death audits in the University Teaching Hospital Bogodogo (UTH-B) of Ouagadougou, Burkina Faso. Materials and Method: This was a prospective study that took place over a year from 1 January to 31 December 2017. It concerned maternal deaths that occurred during this period in the obstetrics and gynecology department of the University Teaching Hospital Bogodogo (UTH-B). All maternal deaths were systematically audited by the audit committee; interviews with providers and families were sometimes conducted. The record books of all patients were analyzed by the audit committee; if necessary, interviews were conducted with care providers and families. The main information collected were recorded on individual files, entered and analyzed using the software Epi-info 7. Result: During the study period, we recorded 32 maternal deaths i.e., 587 per 100,000 live births. Deceased women under age 20 were the most numerous, followed by women aged 20 to 24. The death occurred in most cases in the puerperium in 69.80% of cases. Complications of pregnancy were the most incriminated causes in maternal deaths. Bleeding was the leading cause, accounting for 34.3%. They are followed by hypertensive disorders of pregnancy (21.8%) and infections (18.8%). In the contributing factors, resource factors were incriminated in 56.2% of cases, social factors in 43.7% of cases and medical factors in 25.4% of cases. How to cite this paper: Adama, O., Smaila, O., Natacha, L.B.C., Paul, K.D., Aline, T.S., Charlemagne, O.M., Ali, O. and Blandine, T.B. (2018) Causes of Maternal Mortality According to Reports of Maternal Death Audits in the University Teaching Hospital Bogodogo (UTH-B) from January to December 2017. Open Journal of Obstetrics and Gynecology, 8, 1345-1353. https://doi.org/10.4236/ojog.2018.813136 Received: October 6, 2018 Accepted: November 9, 2018 Published: November 12, 2018 Copyright © 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access


Introduction
Awareness of the quality of care as a determinant in the reduction of maternal mortality leads to a process of critical and systematic analysis of the quality of medical care by comparing procedures or services with reference to quality standards, in order to make corrections [1].Burkina Faso, a west African developing country, had made considerable progress in combating maternal mortality and the maternal mortality ratio decreased from 566 per 100,000 live births in 1993 to 484 per 100,000 in 1998 and 341 per 100,000 in 2010 [2].The known causes of maternal death are dominated by bleeding, dystocia, infections and complications of arterial hypertension [3].These causes of death often reflect a lack of obstetric supervision and care, thus calling into question the quality of patient management in health facilities.In addition to the medical cause of maternal death, the audit highlights all the contributing factors that contributed to the death.It is knowledge of these factors that will enable relevant recommendations to be made at the end of the audit to resolve the relevant and priority problems identified.In the University Teaching Hospital Bogodogo (UTH-B), and more specifically at the maternity ward, there is already a team in charge of recording maternal deaths and organising audit sessions.Thus, we felt it necessary to conduct this study to report the experience of our obstetrical team on maternal death audits.

Patients and Method
It was a retrospective study that focused on women who died in the obstetrical gynecology department of the University Teaching Hospital Bogodogo (UTH-B) of Ouagadougou, Burkina Faso.It had been held over a period of one year from January 1, 2017 to December 31, 2017.Included were all women admitted alive to the UTH-B maternity ward who died during the study period and who met the World Health Organization (WHO) definition of maternal death.According to WHO, maternal death is defined as "the death of a woman during pregnancy or within 42 days of its termination, regardless of its duration and location, for any cause determined or aggravated by pregnancy or the care it caused, but neither accidental nor adventitious" [1].The medical records of deceased patients were the primary sources of information.These files were analysed by the audit committee; where necessary, interviews were held with service providers and families.All deaths were systematically analysed by the audit committee; interviews with providers and families were sometimes conducted.It should be noted that the audit of each case usually begins with the staff or questions are asked to understand the case and at the same time challenge all actors to redouble their efforts to ensure optimal care offered to patients.Some of the cases audited were presented in plenary sessions and resulted in recommendations.At each restitution session, each recommendation is entrusted to an agent who is responsible for it.This person is responsible for implementing the recommendation in question.Four (4) restitution sessions were conducted and resulted in recommendations.We got the approval of the Ethics Committee on Research.The main information collected was recorded on individual sheets, entered and analysed using the Epi-info 7 software.

Mortality Ratio
During the study period, we recorded 32 maternal deaths i.e., 587 per 100,000 live births (LB).

Distribution of Patients According to the Number of Anterior Childbirth
The distribution of patients according to the number of anterior childbirth is shown in Figure 2.

Period of Death
Death occurred during pregnancy in 69.80% of cases (Figure 3).

Distribution of Direct and Indirect Causes of Maternal Death
Death was related to a direct cause in 73% of cases.Indirect causes accounted for 27%.The distribution of deaths by cause is shown in Table 1.

Medical Factors
Table 2 shows the distribution of medical factors contributing to death.
Delay at referral and incorrect treatments were encountered in 12.7% and 6.3% respectively.

Resource-Related Factors
Table 3 shows the distribution of factors related to resources contributing to death.Among the contributing factors related to resources, the lack of SLP and the lack of essential drugs were 28.6% and 15.9% respectively.

Social Factors
Table 4 shows the distribution of the social factors contributing to deaths.

Epidemiological Aspects
The mortality ratio in our study was 587 per 100,000 LB.It is clearly lower than that reported during a study in the same centre in 2012 [4].
The average age was 26 years in our study.This average age is comparable to that reported by OUEDRAOGO [4], ALIHONOU and collaborator [5]  Nulliparous women were the most represented in our study, at 28.6%.We find this explanation in the fact that young women were the most represented in our study.MBONGO BE and collaborators [8] in Brazzaville in Congo reported in their study in 2008 a predominance of primiparous women.Death occurred postpartum in 69.8% of cases.Indeed, post-natal periods are also dangerous and require special attention from health workers and families.Unfortunately, the high workload and sometimes the negligence of health workers and families mean that vigilance decreases once women give birth, thus explaining the high number of deaths in the postpartum period.Our figures are comparable to those of TRAORE in Mali, which reported 59.5% postpartum deaths in its series.

The Causes of Maternal Death
The causes of death are dominated by haemorrhages in (33.3%), followed by hypertensive disorders of pregnancy with (28.8%) and infections (17.5%).
Bleeding in most African series is the leading cause of death [3] [4] [9].They may reflect the significant dysfunction in the care provided by health services and the lack of SLPs.BOUVIER Colle M-H and colleagues [10] in France reported bleeding as the leading cause of death in 2004.Hypertensive pregnancy disorders ranked second in our series.This classification is comparable to that of BA M-G [11] in Senegal which classified eclampsia as the second cause of death in its series.In the OUEDRAOGO C and BOUVIER-Colle M-H [3] series, the second cause of death is contested by infection and eclampsia.Causes of death due to pregnancy complications accounted for 73.0% in our study.PRUAL [12] of the AQUASOU project reported in 2004 in its publication 79% of direct medical causes of maternal deaths in developing countries SAIZENOU [13] and collaborators in Benin reported in 2006 in their series 74% of direct causes of maternal deaths.The direct causes of death would reflect the quality of follow-up during pregnancy and childbirth.They therefore call on all actors to make greater efforts in the care of pregnant women.

Contributing Factors
Medical factors that contributed to deaths, delay at referral, incorrect treatments were the most observed.Patients evacuated to UTH-B sometimes arrive in a very critical state, complicating their care.Although most of the referrals were made by ambulance, most of them were not medicalized despite their critical condition at the time of evacuation.The plenary sessions to present the audits or all the health actors of the city of Ouagadougou were invited to solve even this dysfunction linked to the references.As highlighted by PRUAL A. [12], and TOURE B. [14] in Côte d'Ivoire, the role of providers is considerable in the occurrence of maternal mortality.This was also noted by RICHARD F. and colleagues [15] who mentioned the lack of enforcement of agents in their series.Factors related to resources, lack or insufficiency in SLP were noted several times (28.6%) of the cases.This same observation was made by SAIZENOUS J. and collaborators [13] in their 2006 series in Benin.
The lack of essential medicines (15.9%) is a factor limiting the rapid response of health services.Prescriptions given to parents for urgent cases will take several minutes or even hours to be filled due to the long queue at UTH-B's pharmaceutical depot.Also the incompleteness of emergency kits is a significant contributing factor.Of the contributing social factors, the delay in consultation was noted as in 20.6% of cases.This social factor was also reported by ALIHONOU and collaborator [5] in Benin in their study on escapement audits.Indeed, some patients consulted for the first time at a very advanced stage of the disease, as evidenced by the short delay between admission and death and the significant alteration of their condition at admission.This social phenomenon could be explained partly by ignorance, the lack of financial resources of the populations and partly by the loss of public confidence in health services.The use of traditional products (6.3%), home deliveries (4.8%) unassisted (4.8%) are social factors nowadays that negatively influence the health of the population.Audits with population interviews are the only opportunities for health workers to assess the perception of health services by the population.In this context, audits will enable health services to be adapted to the needs of the population so that these services can be harmoniously integrated into their social environment.GUNAWAN S.
[16] in Indonesia reported delay in consultation as the primary contributing factor to maternal deaths.

Conclusion
Maternal mortality is a major public health problem at the maternity hospital of the university hospital Bogodogo.Hemorrhage is the first cause of death.Hypertensive diseases are more and more worrying.Initiatives need to be taken to address this problem, which hampers the capture of the demographic dividend.

Figure 1
Figure 1 below shows the age distribution of women.The average age is 26.57years with extremes of 17 and 47 years.

Figure 2 .
Figure 2. Distribution of deceased according to the number of anterior childbirth.

Figure 3 .
Figure 3. Distribution of deceased women according to the period of death during pregnancy.

Table 1 .
Distribution of causes of death.

Table 2 .
Distribution of medical factors.

Table 3 .
Distribution of resource factors.

Table 4 .
Distribution of social factors.