A Kind of Improved Susceptible-Infected Model

By analyzing the susceptible-infected model, susceptible-infected-recovered-susceptible model and susceptible infectedrecovered model, we get the improved Kermachk-Mckendrick model. And by applying the controlled threshold value, we get the conditions of isolated rate for infectious disease eventually disappeared.


Introduction
With the acceleration of global economy, the contact and communication among people are more and more frequent.In addition, as the environmental pollution is increasingly serious, more and more infectious diseases have brought huge impact and harm to human beings.Infectious diseases prediction is an important scientific controlled means for infectious diseases, so how to forecast infectious diseases accurately is an important issue in the field of current medical research [1].At present, the forecasting methods for infectious diseases are mainly qualitative prediction [2], quantitative prediction and comprehensive prediction [3].The quantitative prediction has many methods, including regression analysis [4], gray system [5], markov chain [6] and neural network [7] forecasting method.Using mathematical models to forecast the popular trend of infectious diseases has become a consensus and further can help find the spread mechanism of infectious disease.In this paper, mathematical models for several kinds of common infectious diseases were reviewed, and by analysing the controlled threshold value of Kermachk-Mckendrick model, we obtain the isolation rate of infectious diseases terminated.It is conducive for government departments to take effective measures to prevent the further spread of infectious diseases, and control the spread of infectious diseases effectively.

Susceptible Infected Model
Supposed the total number in examined area remains the same at the spread of disease period, regardless of people's life and death and migration, population are divided into healthy subjects and patients, the two in proportion of the total number are ( ) s t and at moments respectively, is the proportion of patients at the initial time, and Assume that the average number of each patient contact effectively at every day is a constant .That is to say, turn the healthy subjects into infected patients when the patients contact with healthy subjects effectively.Model is as follows: The model is called Logistic model.We can find ( ) ( ) , That is all people will be infected and become the patient, this is obviously not conform to the truth.So we consider the condition that patient can be cured or immune, the improved models are following.

Susceptible Infected Recovered Susceptible Model
Let infectious diseases be immunity that patients can be cured to be healthy people, on the other hand, healthy people can be infected again, assuming that the proportion of patients healed every day is μ , μ is cure rate for days.The model is as follows: ( ) Supposed the rate of patients daily contact is .
σ is called the contact number and is the number of each patient has contacted effectively during the period of infection.

Susceptible Recovered Model
Assumed that the total number of people is constant N, the proportion of patients, health, and out of proportion is respectively.Let the patient's contact rate be , cured rate be μ , contacted number be λ σ μ = , and .

Kermachk-Mckendrick Model for Epidemics
Assumption 1: the total number of people in the area we study is constant, not changed along with time.Assumption 2: Due to the effects by infectious diseases, the rate of the number of susceptible persons changed along with time is directly proportional to the product of the number of susceptible and infected person.
Assumption 3: Let the speed of the class from the infected person to move out is proportional to the number of infected person at that time.
Assumption 4: Regardless of the natural birth rate and death rate of the population at the area in research time.
The mathematical model of infectious diseases is as follows: By solving the model, we have

Improved Kermachk-Mckendrick Model
the number of ( ) In a word, applying isolation control of susceptible infectious disease model is the key to prevent the spread of susceptible infectious diseases.The isolated rate must meet some conditions, then we can control max I . ( reduced function by ρ .From this theorem we know, if we want to reduce max I , we can complete it by improving ρ , that is to say, we can adopt isolation control to the class I .Let the isolation rate be , and , then we obtain the improved Kermachk-Mckendrick model. Wang, B. Qu and H. Q. Guo, "Mathematical Model of Infectious Disease Prediction," Chinese Journal of HealthStatistics, Vol. 24, No. 5, 2007, pp.536-540.Fu and G. S. Deng, "The Application of the Markov Chain in Forecasting," Journal of Shenyang Normal University (Natural Science Edition), Vol.1, 2009, pp.28-31.is the isolated rate.By theorem 1, we know[7] X. Y. Zhao, "Infectious Diseases of Self-Organizing Neural Network Prediction Research," Journal ofMathematical Medicine, Vol. 23, No. 4, 2012, pp.379-383.