Ten Rules Preventing COVID-19

The new Coronavirus disease or COVID-19 is a contagious viral/immunological systemic disorder with predominantly respiratory features caused by human infection with SARS-CoV-2, which is rapidly spreading from person-to-person all around the world as a pandemic. As long as there is no effective vaccine available to prevent this disease and no definitive treatment is provided to cure it, it is better to prevent this disease by following a series of principles, which are: home quarantine of asymptomatic to mild COVID-19 patients and hospitalization of severe cases, physical distancing, staying at home, handwashing, cleaning and disinfecting high-touch surfaces, face-mask using, cough and sneeze covering, healthy nutritious diet along with the routine life activities and daily exercise, video communication by phone/online with family, and finally practice to relieve stress/anxiety.


Introduction
The new Coronavirus disease is a contagious viral/immunological systemic disorder with predominantly respiratory features caused by human infection with a novel and emerging virus from Beta RNA-Coronavirus group; SARS-CoV-2, that is rapidly spreading from person-to-person all around the world as a pandemic. The SARS-CoV-2 is transmitted from human to human in various ways: 1) Airway: After coughing and sneezing, the viruses are thrown out with macro droplets of saliva (5 -10 micrometers) and landing on the ground immediately up to a distance of 1 meter.
2) Aerosol way or airborne transmission: while talking and breathing (exhaled phase) the viruses are released up to 4 meters in the air with tiny micro-droplets As long as there is no effective vaccine available to prevent this disease and no definitive treatment is provided to cure it, it is better to prevent this disease by following a series of principles.
The Persian scholar of medicine Ebne Sina (980-1037) suspected that some diseases were spread by microorganisms, and to prevent human to human contamination he came up with the method of isolating people for 40 days in Persian is called Cheleh. Traders from Venice saw his success and took this knowledge back to Italy and called it quarantine (forty in Italian). This is the origin of the word quarantine to fight pandemics, another bright idea coming from ancient Persia (Iran). Also, the historical history of using face masks goes back to the civilization of ancient Iran [4].

Methods
The principles of prevention of becoming infected with the SARS-CoV2 as Ten Rules Preventing COVID-19 include: • Home quarantine of asymptomatic to mild COVID-19 patients and hospitalization of severe cases: Self-isolation of asymptomatic to mild COVID-19 patient from others in a specific room as sick room, with face-mask and with no visitors, and if available, with a separate bathroom, while his/her communication with the first level of COVID-19 Referral System or Family Physician could be continued by phone (telemedicine). Resting, warm-keeping, humidifier using and hot shower taking for cough and sore throat, hands cleaning after nose blowing or coughing or sneezing or use the bathroom and especially before eating or preparing foods, drinking plenty of fluids, a healthy nutritious diet and if needed symptomatic therapy are the only treatments available during this period. It is necessary to explain that home quarantine for parents with COVID-19 will not be effective without children's quarantine in another room at home [4] [5] [6] [7].

Results
Following a contact; the transmission probability of virus: 1) From a SARS-CoV-2 carrier without a mask, to a healthy person with a mask is 70% 2) From a SARS-CoV-2 carrier with a mask, to a healthy person without a mask is 5% 3) From a SARS-CoV-2 carrier with a mask, to a healthy person with a mask is 1.5% 4) From a SARS-CoV-2 carrier without a mask, to a healthy person without a mask is ≥90% [3] [4] [5] [6] [7].
In the cases with positive SARS-CoV-2 kit test but without any symptoms/signs or with mild clinical features, four options could be possible: 1) Carrier state for SARS-CoV-2.
3) Pre-symptomatic COVID-19 within the incubation period. 4) Mild COVID-19. The above cases are silent spreaders, who have a major role in the spread of SARS-CoV-2. In other words, they can spread SARS-CoV-2 for up to 2 weeks [7]. If such a person passes by an average of 100 people daily without physical distancing, and both face-masks are not worn; there is a 90% chance, and if only the silent spreader is without a face-mask; there is a 70% chance that the other person will get it. This means that 90 and 70 people will be infected with the SARS-CoV-2 on a daily basis, respectively, of which; 40% will be asymptomatic, 40% will suffer from mild COVID-19, and 20% of cases will be severe/critical and cause hospitalization, and in the end, 5% of all these people will die. Then, if we multiply the resulting numbers by 14, the results are two rows of numbers, which in order from left to right, indicate: the new cases of COVID-19 in the forms of; asymptomatic, mild, hospitalized candidates, and dead cases within 14 days: 504, 504, 252, 63 392, 392, 196, 49 This is due to the presence of an asymptomatic person infected with SARS-CoV-2 that has the personalities of ignorant, thoughtless, selfish, incomprehensible, unconscious, or a complex person that is called "More Dangerous than a Zombie" who refuses to the face-mask is not applied. Of course, provided that the government financially supports the poor and needy in society.
The fate of the COVID-19 patients after home quarantine or self-isolation at home is as follows: 1) Asymptomatic patients can terminate home quarantine after 2 weeks because they carry the virus for up to 2 weeks.
2) Mild patients can terminate home quarantine after 3 weeks because they carry the virus for up to 3 weeks. Provided, of course, that there are criteria for recovery.
3) Hospitalization of mild to moderate cases of COVID-19 who do not or cannot afford home quarantine, in semi-specialized or field Hospital of the level (II) of COVID-19 Referral System. 4) With the occurrence of initial alarming/warning symptom, on the other hand, shortness of breath (new or worsening, for no other cause); the patient must be hospitalized in Corona Hospital Centre of the level (III) of COVID-19 Referral system. 5) Severe to very severe patients should be quarantined in the Corona hospital and then at home for a total of at least 4 to 6 weeks. Provided, of course, that there are criteria for recovery.
So, asymptomatic and mild COVID-19 patients, who make up 80% of cases, recover after 2 to 3 weeks. Moderate to severe COVID-19 patients usually recover within 3 to 6 weeks but the recovery in critical cases of COVID-19 varies with the person [

Conclusion
According to the corresponding author, the combination of quarantine, staying at home, physical distancing, handwashing, face-mask using and cough/sneeze covering are the main foundation of COVID-19 prevention.