Prof. Jane Hoover-PLow

Cleveland Clinic Lerner Research Institute, USA

Email: hooverj@ccf.org

Qualifications

1977 Ph.D., University of California, Biochemical Nutrition
1970 M.S., West Virginia University, Biochemistry
1967 B.S., Marshall University, Medical Technology

Publications(Selected)

1. Sa, Q., Nadeau, J.H., Hoover-Plow, J. Mouse Chromosome 17 Candidate Modifier Genes for Thrombosis.Mamm. Genome 21, 337–349, 2010.
2. Hoover-Plow, J. Does Plasmin have Anticoagulant Activity? Vascular Health and Risk Management 6, 199-205, 2010.
3. Hoover-Plow, J., Shchurin, A., Hart, E., Gong, Y., Schneeman, T., Sha, J. A Physiological Function for Apolipoprotein(a): A Natural Regulator of the Inflammatory Response. Exp. Biol. Med. 234, 28-34, 2009 Featured Article.
4. Hoover-Plow, J.L., Gong, Y., Shchurin, A., Busuttil, S.J., Schneeman, T.A., Hart, E. Strain and Model Dependent Differences in Inflammatory Cell Recruitment in Mice. Inflamm. Res. 57, 457-463, 2008.
5. Sa, Q., Hart, E., Hill, A.E., Sinasac, D.S., Nadeau, J.H., Hoover-Plow, J. Quantitative trait locus analysis and candidate gene identification for hemostasis and thrombosis. Mamm. Genome 19, 406-412, 2008.
6. Gong, Y., Hart, E., Shchurin, A., Hoover-Plow, J. Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice. J. Clin. Invest. 118, 3012-3024, 2008.
7. Hoover-Plow, J., Shchurin, A., Hart, E., Sha, J., Hill, A.E., Singer, J.B., Nadeau, J.H. Genetic background determines response to haemostasis and thrombosis. BMC Blood Disord. 6, 6, 2006.
8. Hoover-Plow, J. Elusive proatherothrombotic role of Lp(a), A new direction? J. Thromb. Haemost. 4, 971–972, 2006.
9. Sha, J., McCullough, B., Hart, E., Shchurin, A., Nassir, F., Davidson, N.O., Hoover-Plow, J. Apo(a) promotes thrombosis in plasminogen deficient mice in a vascular injury model. J. Thromb. Haemost 3, 2281–2289, 2005.
10. Wang, N., Zhang, L,. Miles, L., Hoover-Plow, J. Plasminogen regulates pro-opiomelanocortin processing. J. Thromb. Haemost. 2, 785–796, 2004.
11. Plow, E.F., Hoover-Plow, J. The functions of plasminogen in cardiovascular disease. Trends Cardiovasc. Med. 14, 180–186, 2004.
12. Hoover-Plow, J. Lessons learned from the plasminogen deficient mice.In: Plasminogen: Structure, Activation, and Regulation. (D.M. Waisman, ed.) Kluwer Academic/Plenum Publishers, New York, pp. 159–176, 2003.
13. Oh, C.-W., Hoover-Plow, J., Plow, E.F. The role of plasminogen in angiogenesis in vivo. J. Thromb. Haemost. 1, 1683–1682, 2003.
14. Hoover-Plow, J. The fibrinolytic system and obesity. Thromb. Haemost. 89, 594–595, 2003.
15. Hoover-Plow, J., Ellis, J., Yuen, L. In vivo plasminogen deficiency delays adipocyte differentiation and reduces fat accumulation. Thromb. Haemost. 87, 1011–1019, 2002.
16. Ellis, J., Lake, A., Hoover-Plow, J. Monounsaturated canola oil reduces fat deposition in growing female rats fed a high or low fat diet. Nutr. Res. 22, 609–621, 2002.
17. Simó, J.M., Joven, J., Vilella, E., Ribas, Figuera, L., Virgos, C., Sundaram, I., Hoover-Plow, J.L. Polymorphisms in human apolipoprotein(a) kringle IV-10 and coronary artery disease: relationship to allele size, plasma lipoprotein(a) concentration and lysine binding site activity. J. Mol. Med. 79, 294–299, 2001.
18. Hoover-Plow, J., Yuen, L. Plasminogen binding increased with adipocyte differentiation. Biochem. Biophys. Res. Commun. 284, 389–394, 2001.
19. Hoover-Plow, J., Skomorovska-Prokvolit, O., Welsh, S. Selective behaviors altered in plasminogen deficient mice are reconstituted with intracerebroventricular injection of plasminogen. Brain Res. 898, 256–264, 2001.
20. Simó, J.M., Joven, J., Vilella, E., Ribas, M., Pujana, M.A., Sundaram, I.M., Hoover-Plow, J.L. Impact of apolipoprotein(a) isoform size heterogeneity on the lysine binding function of lipoprotein(a) in early onset coronary artery disease. Thromb. Haemost. 85, 412–417, 2001.

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Last Updated: August, 2012
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