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Biography

Dr. Igor Malyshev

Biomedical Sciences

University of North Texas Health Science Center, USA

Adjunct Professor


Email: iymalyshev1@gmail.com


Qualifications

Doctor of Medical Sciensies, Russian Academy of Medical Sciences, Institute of General Pathology and Pathophysiology, Moscow

Ph.D., USSR Academy of Medical Sciences, Institute of General Pathology and Pathophysiology, Moscow, USSR

M.Sc., Department of Medical Biology, Tomsk Institute of Medicine, Tomsk, Russia


Selected Publications

Books and Monographs

  1. Meerson F.Z., Malyshev I. Phenomenon of adaptive stabilization of structures. NAUKA, 1993. p. 198.
  2. Malyshev I. Stress proteins in biology and medicine. GEOTAR-MEDIA, 2012, p. 174.
  3. Malyshev I. Immunity, tumors and aging: the role of HSP70. SPRINGER, 2013, p. 145.

Journals

  1. Liamina S. V., Vedenikin T. Iu., Borodovitsyna O. A., Kruglov S. V., Malyshev I. Iu. M1 and M2 macrophage phenotypes functional activity as essential components in innate immune response assessment. Ross Fiziol Zh Im I M Sechenova. 2012, Aug; 98 (8): 1030-5. Russian. PubMed PMID: 23155628.
  2. Manukhina E. B., Goryacheva A. V., Pshennikova M. G., Malyshev I. Yu., Mallet R. T., Downey H. F. Protective effects of adaptation to hypoxia in experimental Alzheimer’s disease. Intermittent Hypoxia and Human Disease. L. Xi, T. V. Serebrovskaya, Springer-Verlag London, 2012, p. 155-171.
  3. Kruglov S. V., Bakhtina L. Iu., Kalish S. V., Malysheva E. V., Budanova O. P., Manukhina E. B., Larionov N. P., Malyshev I. Iu. Resistance to acute hypoxia and changes in the phenotype and phenotypic plasticity of macrophages in mice of different genetic strains. Patol Fiziol Eksp Ter. 2012 Jul-Sep; (3): 56-61. Russian. PubMed PMID: 23072113.
  4. Malyshev I. Iu., Kruglov S. V., Liamina S. V. Hypoxia, inflammation and phenotypic plasticity of macrophages: the central role of HIF-1 and NFkappaB. Patol Fiziol Eksp Ter. 2012 Jul-Sep; (3): 42-50. Review. Russian. PubMed PMID: 23072111.
  5. Lyamina S. V., Kruglov S. V., Vedenikin T. Y., Borodovitsyna O. A., Suvorova I. A., Shimshelashvili Sh. L., Malyshev I. Y. Alternative reprogramming of M1/M2 phenotype of mouse peritoneal macrophages in vitro with interferon-ќ≥ and interleukin-4. Bull Exp Biol Med. 2012 Feb; 152 (4): 548-51. English, Russian. PubMed PMID: 22803130.
  6. Liamina S. V., Shimshelashvili Sh. L., Malyshev I. Iu. Surfactant protein D--endogenous regulator of inflammation and immune defense. Patol Fiziol Eksp Ter. 2012 Jan-Mar; (1): 60-6. Review. Russian. PubMed PMID: 22629864.
  7. Liamina S. V., Maev I. V., Iurenev G. L., Malyshev I. Iu. Bronchial asthma and gastroesophageal reflux disease: view of the clinician and pathophysiologist. Ter Arkh. 2011; 83 (6): 73-9. Review. Russian. PubMed PMID: 21786581.
  8. Goryacheva A. V., Kruglov S. V., Pshennikova M. G., Smirin B. V., Malyshev I. Y., Barskov I. V., Viktorov I. V., Downey H. F., Manukhina E. B. Adaptation to intermittent hypoxia restricts nitric oxide overproduction and prevents beta-amyloid toxicity in rat brain. Nitric Oxide. 2010 Dec 15; 23 (4): 289-99. doi: 10.1016/j. niox. 2010. 08. 005. Epub 2010 Sep 4. PubMed PMID: 20804853.
  9. Manukhina E. B., Goryacheva A. V., Barskov I. V., Viktorov I. V., Guseva A. A., Pshennikova M. G., Khomenko I. P., Mashina S. Y., Pokidyshev D. A., Malyshev I. Y. Prevention of neurodegenerative damage to the brain in rats in experimental Alzheimer's disease by adaptation to hypoxia. Neurosci Behav Physiol. 2010 Sep; 40 (7): 737-43. doi: 10.1007/s11055-010-9320-6. Epub 2010 Jul 16. PubMed PMID: 20635216.
  10. Manukhina E. B., Goriacheva A. V., Barskov I. V., Viktorov I. V., Guseva A. A., Pshennikova M. G., Khomenko I. P., Mashina S. Iu., Pokidyshev D. A., Malyshev I. Iu. Prevention of the brain neurodegeneration in rats with experimental Alzheimer's disease by adaptation to hypoxia. Ross Fiziol Zh Im I M Sechenova. 2009 Jul; 95 (7): 706-15. Russian. PubMed PMID: 19803457.
  11. Atochina-Vasserman E. N., Abramova E. V., Tomer Y., Scott P., Nazarov V. A., Kruglov S. V., Beers M. F., Gow A. J., Malyshev I. Y. SP-D-dependent regulation of NO metabolism in lipopolysaccharide-stimulated peritoneal macrophages. Bull Exp Biol Med. 2009 Apr; 147 (4): 415-20. English, Russian. PubMed PMID: 19704937.
  12. Pshennikova M. G., Khomeko I. P., Kruglov S. V., Zelenina O. M., Shimkovich M. V., Malyshev I. Y. Specific response of the organism and blood leukocytes in rats of different genetic strains to hypoxia. Bull Exp Biol Med. 2008 Oct; 146 (4): 411-4. PubMed PMID: 19489308.
  13. Manukhina E. B., Pshennikova M. G., Goryacheva A. V., Khomenko I. P., Mashina S. Y., Pokidyshev D. A., Malyshev I. Y. Role of nitric oxide in prevention of cognitive disorders in neurodegenerative brain injuries in rats. Bull Exp Biol Med. 2008 Oct; 146 (4): 391-5. PubMed PMID: 19489304.
  14. Nazarov V. A., Kruglov S. V., Khomenko I. P., Bakhtina L. Y., Malysheva E. V., Pshennikova M. G., Manukhina E. B., Malyshev I. Y. Inversion of stress response reprogramming phenomenon in lipopolysaccharide-stimulated alveolar macrophages. Bull Exp Biol Med. 2007 Oct; 144 (4): 507-10. PubMed PMID: 18642699.
  15. Manukhina E. B., Kalenchuk V. U., Gavrilova S. A., Goriacheva A. V., Malyshev I. Iu., Koshelev V. B. Organ specificity in nitric oxide storage in the blood vessel walls during adaptation to hypoxia. Ross Fiziol Zh Im I M Sechenova. 2008 Feb; 94 (2): 198-205. Russian. PubMed PMID: 18516851.
  16. Khomenko IP, Bakhtina LY, Zelenina OM, Kruglov SV, Manukhina EB, Bayda LA, Malyshev IY. Role of heat shock proteins HSP70 and HSP32 in the protective effect of adaptation of cultured HT22 hippocampal cells to oxidative stress. Bull Exp Biol Med. 2007 Aug; 144 (2): 174-7. PubMed PMID: 18399273.
  17. Malysheva EV, Kruglov SV, Nazarov VA, Manukhina EB, Malyshev IY. Intracellular and extracellular NO differentially modulates the stress response and apoptosis in macrophages exposed to the influence of biological or physical factors. Bull Exp Biol Med. 2007 Jun; 143 (6): 673-7. English, Russian. PubMed PMID: 18239798.
  18. Monastyrskaya EA, Belkina LM, Manukhina EB, Malyshev IY. Antiarrhythmic effect of heat adaptation in ischemic and reperfusion injury to the heart. Bull Exp Biol Med. 2007 Jan; 143 (1): 9-11. PubMed PMID: 18019000.


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Last updated:2014-3-4