Prof. Aron D. Mosnaim
Rosalind Franklin University of Medicine and Science, USA
Email: Aron.Mosnaim@rosalindfranklin.edu
Qualifications
1977 RPh.,
State of Illinois Pharmacy Board License 051-032662
1969 Ph.D., Strathclyde University, Glasgow, Great Britain, Organic Chemistry
1962 Pharm.D., University of Chile, Santiago, Chile
Publications (Selected)
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Litvak, J., Riesco, J., Atria, A., Lopez, O., Armedariz, R. and Mosnaim, A.D.: Diiodotyrosine
metabolism in endemic goitri. Rev. Med. de Chile. 91:653-655, 1963.
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del Villar, E. and Mosnaim,
A.D.: Effect of DDT on incorporation of C14-labelled glucose
into protein and soluble intermediates of nymphal triatoma infestans. Exp.
Parasitology. 21:186-194,
1967.
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Mosnaim, A.D. and Nonhebel, D.C.:
Reaction of cupric halides with organic compounds. II.9-Halogenoanthracenes.
Tetrahedron. 25:1591-1595,
1969.
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Mosnaim, A.D., Nonhebel, D.C. and
Russell, J.: Reaction of cupric halides with organic compounds, III. 9-Alkyl
and 9-arylanythracenes. Tetrahedron. 25:3485-3492, 1969.
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Gibson, S., Mosnaim, A.D., Nonhebel, D.C. and
Russell, J.: Reaction of cupric halides with organic compounds, V. Reactions of
9,10-dialkyl- and 9-alkyl-10-arylanthracenes. Tetrahedron.25:5047-5057, 1969.
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Mosnaim, A.D.:
Ligand-Transfer reaction of cupric halides with organic compounds. Doctoral
Thesis, Department of Pure and Applied Chemistry, Strathclyde University, Glasgow, Great
Britain, 1969.
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Mosnaim, A.D.:
Ligand-transfer reaction of cupric halides with organic compunds, National
Lending Library, Walton Spa., Yorks, Great Britain, 1969.
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Mosnaim, A.D. and Nonhebel, D.C.:
Reaction of cupric halides with organic compounds. VI. Reactions of 9-alkyl-and
9-aryl-10-halogenoanthracenes. J. Chem. Soc. (C):942-946, 1970.
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Mosnaim, A.D., Nonhebel, D.C. and
Russell, J.: Reaction of cupric halides with organic compounds. VII. Reactions
of 9-alkoxy- and 9-acyloxy-10-alkyl-anthracenes. Tetrahedron. 26: 1123-1129, 1970.
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Wolf, M.E. and Mosnaim,
A.D.: Effect of temperature over alcaline phosphatase isoenzymes. Rev.
Med. de Chile. 97(12):772-774,
1969.
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Flood, J., Mosnaim, A.D. and Nonhebel, D.C.:
Bromination of some substituted 9-methylanthracenes. Chemical Communications. 12:761-762, 1970.
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Mosnaim, A.D., Wolf, M.E. and Nonhebel, D.C.:
Gas-liquid and thin-layer chromatographic determination of some 9- and
9,10-substituted anthracenes. J. Chromatography. 70:154-157, 1972.
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Sabelli, H.C., Giardina, W.J., Mosnaim, A.D. and Sabelli, H.H.: A comparison of the
functional roles of norepinephrine, dopamine, and phenylethylamine in the
central nervous system. Acta Physiological Polonica. 24:33-40, 1973.
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Mosnaim, A.D. and Inwang,
E.E.: A spectrophotometric method for quantification of 2-phenylethylamine in
biological specimens. Analytical Biochemistry. 54:561-577, 1973.
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Mosnaim, A.D., Inwang, E.E.,
Sugerman, J.H., DeMartini, W.J. and Sabelli, H.C.: Ultraviolet spectrophotometric
determination of 2-phenylethylamine in biological samples and its correlation
with depression. Biological Psychiatry. 6(3):235-257, 1973.
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Inwang, E.E., Mosnaim, A.D. and
Sabelli, H.C.: Isolation and characterization of phenylethylamine and
phenylethanolamine from human brain. J. Neurochem. 20:1469-73, 1973.
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Mosnaim, A.D., Inwang, E.E.,
Sugerman, J.H. and Sabelli, H.C.: Identification of 2-phenylethamine in human
urine by infrared and mass spectroscopy and its quantification in normal
subjects and cardiovascular patients. Clinica Chimica Acta. 46:406-413, 1973.
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Mosnaim, A.D., Wolf, M.E.,
Saavedra, I., Amaro, A.M., Cordano, G. and Nonhebel, D.C.: Reaction of
cupric (II) halides with organic compound. VIII. Pyrene and some 3-substituted
pyrenes. Tetrahedron Letters. 17:1491-1494,
1973.
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Mosnaim, A.D., Wolf, M.E.,
Saavedra, I., Rosenkranz, A., Diaz, S. and Nonhebel, D.C.: Gas-liquid
and thin-layer chromatographic determination of some 3- and 3,X-substituted
pyrenes. J. Chromatography. 80:259-262,
1973.
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Inwang, E.E., Madubuike, U.P. and Mosnaim, A.D.: Evidence for the excretion of 2-phenylethylamine
glucoronide in human urine. Experientia. 29(9):1080, 1973.
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Mosnaim, A.D., Sabelli, H.C.
and Inwang, E.E.: The influence of psychotropic drugs on the levels of
endogenous 2-phenylethylamine in rabbit brain. Biolog. Psychiatry. 8(2):227-234, 1974.
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Sabelli, H.C. and Mosnaim,
A.D.: Phenylethylamine hypothesis of affective behavior. American
Journal of Psychiatry. 131:695-699,
1974.
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Sabelli, H.C., Vazquez, A.J., Mosnaim,
A.D. and Madrid-Pedemonte, L.: 2-Phenyle- thylamine as a possible
mediator for 9-tetrahydrocannabinol-induced stimulation. Nature. 248:144-145, 1974.
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Sabelli, H.C., Pedemonte, W.A., Whalley, C., Mosnaim, A.D. and Vazquez, A.J.: Further evidence of a role
of 2-phenylethylamine in the mode of action of 9-tetrahydrocannabinol. Life
Sciences. 14:149-156, 1974.
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Borison, R.L., Mosnaim, A.D. and
Sabelli, H.C.: Biosynthesis of brain 2-phenylethylamine: Influence of
decarboxylase inhibition and D-amphetamine. Life Sciences. 15(10):1836-1848, 1974.
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Sabelli, H.C., Mosnaim, A.D. Vazquez,
A.J., Madrid-Pedmonte, L.: (-)-Trans-tetrahydrocannabinol-induced increase in
brain 2-phenylethylamine: Its possible role in the psychological effect of
marihuana, in J.M. Singh and H. Lal (eds.): Drug Addiction/Volume 3:
Neurobiology and Influences on Behavior. New York: Stratton 1974, pp.
271-284.
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Sabelli, H.C., Mosnaim, A.D. and
Vazquez, A.J.: Phenylethylamine: Possible role in depression and
antidepressive drug action, in R.R. Drucker-Colin and R.D. Myers (eds.):
Advances in Behavioral Biology/Volume 10: Neurohumoral Coding of Brain
Function. New York: Plenum Publishing 1974, pp. 331-357.
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Borison, R.L. Mosnaim, A.D. and
Sabelli, H.C.: Brain 2-phenylethylamine as a mediator for the central actions
of amphetamine and methylphenidate. Life Sciences. 17:1331-1343, 1975.
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Sabelli, H.C., Mosnaim, A.D.,
Vazquez, A.J., Giardina, W.J., Borison, R.L. and Pedemonte, W.A.: Biochemical
plasticity of synaptic transmission: A critical review of Dale's principle.
Biological Psychiatry. 11:481-524,
1976.
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Borison, R.L., Mosnaim, A.D. and
Sabelli, H.C.: Qualification of brain 2-phenylethylamine content by gas-liquid
chromatography and its modification by marihuana. Clinical Research. 23: 550A, 1975.
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Silkaitis, R.P. and Mosnaim,
A.D.: Pathways linking L-phenylalanine and 2-phenyl-ethylamine with
p-tyramine in rabbit brain. Brain Research. 114:105-115, 1976.
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Pedemonte, W.A., Mosnaim,
A.D. and Bulat, M.: Penetration of phenylacetic acid across the
blood-cerebrospinal fluid barrier. Res. Comm. Chemical Pathol. Pharmacol. 14(1):111-116, 1976.
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Rubin, R., Patel, D., Singh, S. and Mosnaim, A.D.: Influence of hyperthyroidism on ethanol metabolism
in rats. Clinical Research. 24:369A,
1976.
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Sabelli, H.C., Mosnaim, A.D., Borison,
R.L. and Wolf, M.E.: Possible role of 2-phenylethylamine in the
modulation of extrapyramidal function in B.N. Dhawan and P.B. Bradley (eds.):
Drugs and Central Synaptic Transmission. Baltimore: University
Park Press, 1976, pp. 164-173.
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Zeller, E.A., Mosnaim, A.D.,
Borison, R.L. and Huprikar, S.V.: Phenylethylamine: Studies on the mechanism of
its physiological action, in E. Costa, E. Giacobini and R. Paoletti
(eds.): Advances in Biochemical Pharmacology/ Volume 15: First and Second
Messengers-New Vistas. New York: Raven Press 1976, pp. 75-86.
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Ungar, F., Mosnaim, A.,
Ungar, B. and Wolf, M.E.: Tyramine binding by synaptosomes from rat
brain: Effect of centrally active drugs. Biological Psychiatry. 12:661-668,
1977.
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Mosnaim, A.D., Edstrand,
D.L., Wolf, M.E. and Silkaitis, R.P.: Evidence for an enzymatic
p-tyramine-dehydroxylating system in rabbit brain preparations in vitro.
Biochemical Pharmacology.26:1725-1728,
1977.
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Ungar, F., Mosnaim, A.D.,
Ungar, B. and Wolf, M.E.: Preliminary studies of the sodium borohydride
stabilizable binding of phenylethylamine and tyramine to brain preparations.
Res. Comm. Chemical Pathol. Pharmacol. 19:427-434, 1978.
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Mosnaim, A.D. and Wolf, M.E.: Biochemical
and pharmacological characterization of the phenylethylamine metabolic pathway,
in A.D. Mosnaim and M.E. Wolf (eds.): Non-Catecholic Phenylethylamines Part 1:
Phenylethylamine: Biological Mechanisms and Clinical Aspects. New York:
Marcel Dekker, Inc. 1978, pp. 3-22.
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Mosnaim, A.D., Wolf, M.E.,
Huprikar, S., Singh, S.P. and Zeller, E.A.: Reduced monoamine oxidase activity
in blood platelets from insulin-dependent diabetics. Diabetes. 28:455-456, 1979.
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Ungar, F., Ungar, B., Alivisatos, S., Mosnaim, A.D. and Wolf, M.D.: Non-enzymic interactions of
nicotinamide adenine dinucleotide of some of its synthetic analogue and other
compounds with orthophosphate. Res. Comm. Chemical Pathol.
Pharmacol. 25:395-398,
1979.
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Mosnaim, A.D., Silkaitis, R.
and Wolf, M.E.: Rabbit brain metabolism of phenylethylamine and
tyramine: Drug effects. Life Sciences. 27:557-566, 1980.
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Hansen, T.R., Greenberg, J. and Mosnaim, A.D.: Direct effect of phenylethylamine upon isolated
vascular smooth muscle of the rat. Europ. J. Pharmacology. 63:95-101, 1980.
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Alcorn, W.C., Cromarty, F.M., Flood, J., Mancilla, J.M., Mosnaim, A.D., Nonhebel, D.C. and
Scullion, I.: Reactions of copper (II) halides with aromatic compounds. Part
XIII. The mechanisms of halogenation of some substituted 9-methylanthracenes.
J. Chemical Research. 3:102-103,
1980.
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Mosnaim, A.D., Wolf, M.E.,
Callaghan, O. and Ungar, R.: Tyramine: metabolic and binding studies, in A.D.
Mosnaim and M.E. Wolf (eds.): Non-catecholic Phenylethylamines Part
2: Phenylethanolamine, Tyramines and Octopamines. New York: Marcel
Dekker, Inc. 201-229, 1980.
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Mosnaim, A.D., Callaghan,
O.H. and Wolf, M.E.: Determination of non-catecholic
phenylethylamines and monomethylated derivatives of phenylethylamines. J.
Chromatography. Biomedical Applications 224:481-487, 1981.
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Wolf, M.D., Bowie, L., Keener, S., and Mosnaim, A.D.: Prolactin response in tardive dyskinesia.
Biological Psychiatry. 17:485-490,
1982.
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Wolf, M.E., Ryan, J.J. and Mosnaim, A.D.: Organicity and tardive dyskinesia. Psychosomatics.23:475-480, 1982.
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Wolf, M.E., Almy, G., Toll, M. and Mosnaim, A.D.: Mania associated with the use of Baclofen.
Biological Psychiatry. 17:757-759,
1982.
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Mosnaim, A.D., Karoum, F.,
Zeller, A., Callaghan, O.H., Singh, S.P. and Wolf, M.E.: Platelet
monoamine oxidase activity and plasma levels of non-catecholic
phenylethylamines in insulin-dependent diabetic subjects. Clinica Chimica Acta. 126:237-242, 1982.
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Mosnaim, A.D., Wine, R.,
Karoum, F., Diamond, S. and Wolf, M.E.: Methionine enkephalin,
phenylethylamine, phenylacetic acid, platelet monoamine oxidase and prolactin
in plasma of migraine patients. Clinical Pharmacology Therapeutics. 31(2): 251-252, 1982.
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Wolf, M.E. and Mosnaim,
A.D.: Phenylethylamine in neuropsychiatric disorders. Gen. Pharmacology 14(4):385-390, 1983.
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Wolf, M.E., Keener, S., Mathis, P. and Mosnaim, A.D.: Phenylethylamine-like properties of Baclofen.
Neuropsychobiology. 9:219-22,
1983.
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Wolf, M.E. Chevesich, J.E., Lehrer, E. and Mosnaim, A.D.: The clinical
association of tardive dyskinesia and drug induced Parkinsonism. Biol.
Psychiatry. 13(10):1181-1188,
1983.
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Mason, M., Wolf, M.E. and Mosnaim, A.D.: Studies on the mechanism of phenyle- thylamine
uptake by rabbit erythrocytes. Compar. Biochem. Physiology. 76C:215-219, 1983.
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Wolf, M.E., Almy, G., Mathis, P. and Mosnaim, A.D.: Baclofen therapy in psychiatric patients. Clinical
Pharmacology and Therapeutics. 33(2):244,
1983.
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Wolf, M., Ryan, J. and Mosnaim,
A.D.: Cognitive functions in tardive dyskinesia. Psychological Medicine. 13(3):671-674, 1983.
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Wolf, M.E., Chevesich, J. and Mosnaim, A.D.: Trunkal tardive dyskinesia. Neurology. 33(4), Supp. 2:198, 1983.
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Karoum, F., Chuang, Lin-Whei, Mosnaim,
A.D., Staub, R.A., and Wyatt, R.J.: Plasma and cerebrospinal fluid
concentration of phenylacetic acid in humans and monkeys. J. Chrom. Sciences.21:546-550, 1983.
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Mosnaim A.D., Wolf, M.E. and
Madubuike U.P.: Presence and biosynthesis of phenylacetic acid in the rabbit
brain. Biochem. Pharmacology. 33(12):1993-1996,
1984.
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Wolf, M.E., Koller, W.C. and Mosnaim, A.D.: Electroencephalogram studies in tardive
dyskinesia. Clinical Electroencephalography. 15(4):222-225, 1984.
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Wolf M.E. and Mosnaim A.D.:
Tardive dyskinesia subtypes. Hospital Community Psychiatry.35(8):828-830, 1984.
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Mosnaim, A.D., Wolf, M.E.,
and Szanto, P.: Butaperazine effects on plasma methionine-enkephalin levels in
patients with tardive dyskinesia. Res. Comm. Substance Abuse. 5(4):313-316, 1984.
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Mosnaim, A.D., Wine, R.,
Diamond, S. and Wolf, M.E.: Plasma methionine enkephalin levels
during migraine episodes, in F.C. Rose (ed.): Progress in Migraine Research,
Vol. 2. London, England: Pitman Book Ltd. 151-161, 1984.
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Paulos, M.A., Mosnaim, A.D., Wolf, M.E. and
Tessel, R.E.: Phenylethylamine, phenylacetic acid and methionine enkephaline
levels in humans following profound acute stress, in A. Boulton, G. Baker,W.
Dewhurst and M. Sandler (eds.): Neurobiology of Trace Amines. New
Jersey: Humana Press 563-569, 1984.
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Wolf, M.E. and Mosnaim,
A.D.: Phenylethylamine and tardive dyskinesia, in A. Boulton, G. Baker,
W. Dewhurst and M. Sandler (eds.): Neurobiology of Trace Amines. New
Jersey: Humana Press 557-562, 1984.
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Callaghan, O., Mosnaim, A.,
Chevesich, J. and Wolf, M.: The kinetics of hydroxylation of phenylethylamine,
amphetamine and phenylalanine in rodent tissues, in A. Boulton, G. Baker, W.
Dewhurst and M. Sandler (eds.): Neurobiology of Trace Amines. New Jersey:
Humana Press 307-312, 1984.
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Mosnaim, A.D., Wolf, M.E. and
Diamond, S.: Non-catecholic phenylethylamines and MAO activity in
diabetes and migraine, in A. Boulton, G. Baker, W. Dewhurst and M. Sandler
(eds.): Neurobiology of Trace Amines. New Jersey: Humana Press 549-566,
1984.
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Mosnaim, A.D., Wolf, ME.
And Zeller, E.A.: Degradation kinetics by MAO of PEA derivatives. A model
for the molecular basis of their analgesic and behavioral effects?, in A.
Boulton, G. Baker, W. Dewhurst and M. Sandler (eds.): Neurobiology of
Trace Amines. New Jersey: Humana Press 299-306, 1984.
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Wolf, M.E., Javaid, J.I., Mosnaim, A.D. and Davis, J.M.: Butaperazine kinetics in
patients with tardive dyskinesia. Biopharmaceutics and Drug Disposition. 6:223-227, 1985.
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Mosnaim, A.D., Wolf, M.E.,
Chevesich, J., Callaghan, O.H. and Diamond, S.: Plasma methionine-enkephalin
levels. A biological marker for migraine? Headache. 25(5):259-261, 1985.
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Wolf, M.E., De Wolfe, A., Ryan, J., Lips, O. and Mosnaim, A.D.: Vunerability to tardive
dyskinesia. J. Clinical Psychiatry. 46:367-368, 1985.
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Wolf, M.E., Mosnaim, A.D.,
Owens, R., Paulos, M. and Hoffman, H.E.: Molindone pharmacokinetics in
psychiatric patients. Res. Comm. Psychol. Psychiatry Behavior. 10(3):215-220, 1985.
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Mosnaim, A.D., Chevesich, J., Wolf, M.E.,
Freitag, D.O. and Diamond, S.: Plasma methionine-enkephalin. Increased levels
during a migraine episode. Headache. 26(6):278-281, 1986.
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Wolf, M.E. and Mosnaim,
A.D.: Lithium and molindone interactions: pharmacokinetic studies.
Res. Comm. Psychol. Psychiatry Behavior. 11(1):23-28, 1986.
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Mosnaim, A.D., Wolf, M.E.,
Chevesich, J., Callaghan, O.H. and Szanto, P.: Phenylethylamine metabolism by
postmortem human brain and liver preparations, in A. Boulton, et al., eds.:
Neuropsychopharmacology of the trace Amines. New Jersey: Humana Press
487-498, 1986.
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Wolf, M.E., Mosnaim,
A.D., Callaghan, O.H., Chevesich, J. and Caro, M.: Phenylethylamine
metabolism to tyramine by postmortem human brain preparations. Life Sci. 40(5):489-494, 1987.
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Wolf, M.E., DeWolfe, A. and Mosnaim, A.D.: Risk factors for tardive dyskinesia according to
primary psychiatric diagnostic. Hillside J. Clinical Psychiatry. 9(1):3-10, 1987.
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Mosnaim, A.D., Diamond, S.,
Freitag, F., Chevesich, J., Wolf, M.E. and Solomon, G.: Plasma
and platelet methionine-enkephalin levels in chronic cluster patients during an
acute headache episode. Headache. 27(6):325-328,
1987.
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Wolf, M.E., Alavi, A. and Mosnaim, A.D.: Pharmacological interventions in Vietnam
Veterans with post traumatic stress disorder. Res. Comm. Psychol. Psychiatry
Behavior. 12(3):169-176,
1987.
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Wolf, M.E., Alavi, A. and Mosnaim, A.D.: Aids related complex in a Vietnam Veteran with drug
abuse. Res. Comm. Substance Abuse. 8:117-123,
1987.
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Diamond, S., Mosnaim, A.D.,
Freitag, F., Wolf, M.E., Lee, G. and Solomon, G.: Plasma methionine-enkephalin
in patients with cluster headache, in F.C. Rose (ed.): Advances in Headache
Research, Vol. 4, London: John Libbey & Co. Ltd. 4: 209-219, 1987.
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Wolf, M.E., Alavi, A. and Mosnaim, A.D.: Post traumatic stress disorder in Vietnam
Veterans: Clinical-EEG findings; possible therapeutic effects of carbamazepine.
Biological Psychiatry. 23:642-644,
1988.
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Mosnaim, A.D., Puente, J., Wolf, M.E.,
Callaghan, O.H., Busch, R. and Diamond, S.: Studies of the in vitro human
plasma degradation of methionine-enkephalin. Gen. Pharmacology. 19(5):729-733,
1988.
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Wolf, M.E., Alavi, A. and Mosnaim, A.D.: Pain, dermatological and allergic conditions in
post traumatic stress disorders. Res. Comm. Psychol. Psychiatry Behavior. 13(3):237-240, 1988.
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Mosnaim, A.D. and Wolf, M.E.:
Administration of butaperazine and plasma methionine- enkephalin levels in
schizophrenic and affective disorder patients with tardive dyskinesia. Journal
Clinical Psychopharmacology. 8(4):Suppl.
275-315, 1988.
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Mosnaim, A.D., Callaghan,
O.H. and Wolf, M.E.: Hydroxylation of phenylethylamine by rat liver
preparations. Gen. Pharmacology. 19(5):729-733,
1989.
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Ayre, S., Skalestski, B. and Mosnaim,
A.D.: Blood-brain barrier passage of azidothymidine in rats: effects of
insulin. Res. Comm. Chemical Pathology Pharmacology. 63(1):45-52, 1989.
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Mosnaim, A.D., Diamond, S., Wolf, M.E.,
Puente, J. and Freitag, F.: Endogenous opioid-like peptides in headache. An
overview. Headache. 29(6):368-372,
1989.
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Mosnaim, A.D., Wolf, M.E.,
Lee, G., Puente, J., Garmnerdsiri, S., Freitag, F. and Diamond, S.: Plasma
degradation of methionine-enkephalin by cluster headache patients. In vitro
studies. Headache Quarterly. Current Treatment and Research. 1(1):79-83, 1990.
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Mosnaim, A.D., Huprikar, S., Wolf, M.E. and
Diamond, S.: Platelet monoamine oxidase in female migraine patients. Headache. 30(8):488-490, 1990.
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Wolf, M.E., Mosnaim,
A.D., Puente, J. and Ignacio, R.: Methionine-enkephalin in post
traumatic stress disorder. Plasma levels and degradation. Res. Comm. Psychology
Psychiatry. Behavior 15(1-2):73-78,
1990.
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Wolf, M.E., Mosnaim,
A.D., Ignacio, R. and Puente, J.: Plasma
methionine-enkephalin in post-traumatic stress disorder. Biological Psychiatry. 29:305-307, 1991.
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Maturana, P., Miranda, D., Sepulveda, C., Puente, J., Wolf, M.E.,
and Mosnaim, A.D.: Natural
killer cell activity in patients with septic shock. J. Critical Care. 6:42-45, 1991.
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Wolf, M.E., Caro, M., and Mosnaim, A.D.: Lithium-neuroleptic interactions:
Electroencephalographic studies. Res. Comm. Psychol. Psychiatry Behavior. 16(1-2):35-40, 1991.
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Mosnaim, A.D., Huprikar, S., Wolf, M.E.,
Freitag, F. and Diamond, S.: Studies of platelet monoamine oxidase activity during
an acute cluster headache attack. Cephalalgia. 11(supp.11): 254-255, 1991.
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Wolf, M.E., de Wolfe, A.S. and Mosnaim, A.D.: The association of tardive dyskinesia with
cognitive deficits. A review. Res. Comm. Psychol. Psychiatry Behavior. 16 (1-2):15-27, 1991.
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Mosnaim, A.D., Huprikar, S., Wolf, M.E.,
Freitag, F. and Diamond, S.: Studies of platelet monoamine oxidase activity in
female migraineurs. An old story revisited, in F.C. Rose (ed.): New Advances in
Headache Research: 2, London: Smith-Gordon
and Co. Ltd. 135-139, 1991.
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Puente, J., Maturana, P., Miranda, D., Navarro, C., Wolf, M.E. and Mosnaim, A.D.: Enhancement of human
natural killer cell activity by opioid peptides: similar response to
methionine-enkephalin and B-endorphin. Brain, Behavior Immunity. 6:32-39, 1992.
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Mosnaim, A.D., Huprikar, S., Wolf, M.E.,
Callaghan, O.H., Freitag, F. and Diamond, S.: Platelet monoamine oxidase
activity in cluster headache patients. Headache Quarterly. Current Treatment
and Research. III(2):172-176, 1992.
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Wolf, M.E., Mosnaim, G., Farinha, P. and Mosnaim, A.D.: Reinduction of neuroleptic malignant syndrome by
lithium. Res. Comm. Psychol. Psychiatry Behavior. 17:69-72, 1992.
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Mosnaim, A.D.: Role of
enkephalins and endorphins in headaches. In: Symposium "Neurobiologic
Mechanisms as an Approach to the Pharmacology of Headache. (G. Solomon, ed.),
Headache Quarterly. Current Treatment and Research. 3(3),309-318, 1992.
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Mosnaim, A.D.: Role of
enkephalins in the regulation of pain in migraine and cluster headaches.
National Headache Foundation Letter, pp.13, Summer 1992.
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Mosnaim, A.D., Wolf, M. E.,
Maturana, P., Mosnaim, G., Puente, J., Kucuk, O. and Gilman-Sachs, A.: In vitro
natural killer cell activity in post traumatic stress disorder patients.
Response to methionine-enkephalin challenge. Immunopharmacology. 25:107-116, 1993.
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Mosnaim, A.D., Wolf, M. E.,
Maturana, P., Puente, J., Freitag, F. and Diamond, S.: In vitro studies of
natural killer cell activity in migraineurs. Changes in response to
methionine-enkephalin challenge during an acute migraine episode. Headache
Quarterly. Current Treatment and Research.4(1):36-41, 1993.
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Puente, J., Carvajal, T., Parra, S., Miranda, D., Sepulveda, C., Wolf, M.E. and Mosnaim, A.D.: In vitro studies of
natural killer cell activity in septic shock patients. Response to a challenge
with alpha-interferon and interleukin-2. International J. Clinical Pharmacology
Therapeutics Toxicology.31(6):271-275,
1993.
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Wolf. M.E., Richer, S., Berk, M.A. and Mosnaim, A.D.: Cutaneous and ocular changes associated with the
use of chlorpromazine. International J. Clinical Pharmacology Therapeutics
Toxicology. 31(8):365-367,
1993.
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Mosnaim, A. D.: Symposium
participant "New and Old Therapy for Vascular Headaches" (proceedings
edited by Journal's staff). P&T (Pharmacy and Therapeutics. A Peer Reviewed
Journal for Formulary Management). 18(6):575-582,
1993.
-
Mosnaim, A.D.: Biochemical
and immunological studies in migraine and cluster headaches. In: Symposium
"New and Old Therapies of Vascular Headaches: Immune Approaches and
Serotonin Receptors in Therapy". (A.D. Mosnaim proceedings ed). Headache
Quarterly. Current Treatment and Research. 34-38: 1994.
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Puente, J., Carvajal, T., Parra, S., Miranda, D., Sepulveda, C., Wolf, M.
E., and Mosnaim, A. D.:
Enhancement of natural killer cell activity in septic shock patients by a
mixture of the calcium ionophore A23187 and the phorbol ester TPA. In vitro
studies. International J. Clinical Pharmacology Therapeutics Toxicology. 32(1):19-23, 1994.
-
Wolf, M. E. and Mosnaim, A.
D.: Improvement of axial dystonia with the administration of clozapine.
International J. Clinical Pharmacology Therapeutics Toxicology. 32(6):282-283, 1994.
-
Mosnaim, A. D., Wolf, M. E.,
Maturana, P., Puente, J., Freitag, F. and Diamond, S.: In vitro studies of
natural killer cell activity in migraineurs. Changes in response to a
B-endorphin challenge during an acute migraine episode. Headache Quarterly.
Current Treatment and Research. 2:142-148,
1994.
-
Mosnaim, A. D.: Biochemical
and Immunological Studies in Migraine Headache. National Headache Foundation
Newsletter, pp. 4-5, Winter 1994 (No. 87).
-
Ranade, V.V., Wolf, M.E. and Mosnaim, A.D.: Generic drug industry: Current status and future
prospects. Drug News & Perspectives. 197-204, 1994.
-
Wolf, M.E. and Mosnaim,
A.D.: Polypharmacy: a problem of the decade of the nineties. Drug News
& Perspectives. 581-584, 1994.
-
Ranade, V.V., Wolf, M.E. and Mosnaim, A.D.: Developments in antiarrhythmic drugs: An overview.
Expert Opinion Investigational Drugs. 4(11):1-29, 1995.
-
Puente, J., Diaz, M.A., Salas, M.A., Miranda, D., Gaggero, A., Wolf, M.E. and Mosnaim, A.D.: Studies of natural
killer cell activity in a drug-free, healthy population. Response to a
challenge with taxol, estramustine and lipopolysaccharide. International J.
Clinical Pharmacolology Therapy.33(8):457-461,
1995.
-
Mosnaim, A.D., Wolf, M.E.,
Curr, M., Mosnaim, J.M., Freitag, F. and Diamond, S.: Myths in migraine
research: 1. Migraine and cluster headache patients are characterized by
significant alterations in platelet monoamine oxidase activity. Headache
Quarterly. Current Treatment and Research.7(3):225-234, 1996.
-
Mosnaim, A.D., Freitag, F.,
Ignacio, R., Salas, M.A., Karoum, F., Wolf, M.E. and Diamond,
S.: Apparent lack of correlation between tyramine and phenylethylamine content
and the occurrence of food-precipitated migraine. Reexamination of a variety of
food products frequently consumed in theUnited States and commonly
restricted in tyramine-free diets. Headache Quarterly. Current Treatment and
Research. 7(3):239-249,
1996.
-
Puente, J., Salas, M.A., Cañon, C., Miranda, D., Wolf, M.E. and Mosnaim, A.D.: Activation of protein
tyrosine kinase: a possible requirement for fixed-bacteria and
lipopolysaccharide-induced increase in human natural killer cell. Int. J.
Clinical Pharmacology Therapy. 34(5):212-218,
1996.
-
Wolf, M.E., De Wolfe, A.S. and Mosnaim, A.D.: Cognitive deficits in tardive dyskinesia, in: R.
Yassa, V. Nair and D. Jeste (eds.): Neuroleptic Induced Movement Disorders. Cambridge UniversityPress, United
Kingdom 196-206, 1996.
-
Sepúlveda, C., Puente, J., Weinstein, C., Wolf, M.E. and Mosnaim, A. D.: Enhancement of natural
killer cell activity in HIV-1 infected subjects by a mixture of the calcium
ionophore A23187 and the phorbol ester TPA. Lack of response to a similar
challenge with interleukin-2 or alpha-interferon. American J. Therapeutics. 4(11-12):413-421, 1997.
-
Karoum, F., Wolf, M.E. and Mosnaim, A.D.: Effects of the administration of amphetamine,
either alone or in combination with reserpine or cocaine, on regional brain
beta-phenylethylamine and dopamine release. American J. Therapeutics. 4(9-10):333-342, 1997.
-
Mosnaim, A.D., Kulaga, H.,
Adams, J.A., Wolf, M.E., Freitag, F. and Diamond. S.: Flow cytometric
analysis of lymphocyte subsets in migraine patients during and outside of an
acute headache attack. Cephalalgia. 18(4):197-201, 1998.
-
Wolf, M.E., Moffat, M., Ranade, V., Somberg, J.C., Lehrer, E. and Mosnaim, A.D.: Lithium, hypercalcemia
and arrythmia. J. Clin. Psychopharmacology. (Peer reviewed Letter). 18:420-423,
1998.
-
Miranda, D., Puente, J., Blanco, L., Wolf, M.E. and Mosnaim, A.D.: In vitro effect of
bacterial lipopolysaccharide on the cytotoxicity of human natural killer cells.
Res. Comm. Molecular Pathology Pharmacology. 100(1):3-14, 1998.
-
Valenzuela, M. A., Cartier, L., Collados, L., Kettlun, A. M., Araya, F.,
Concha, C., Flores, L., Wolf, M. E. and Mosnaim, A. D.: Gelatinase activity of matrix metalloproteinases
in the cerebrospinal fluid of various patient populations. Res. Comm. Chemical
Pathology Pharmacology. 104(1):42-52,1999.
-
Ranade, V., Molnar, J., Khokher, T., Agarwal, A., Mosnaim, A.D. and Somberg, J.: Effect
of angiotensin-converting enzyme therapy on QT interval dispersion. American J.
Therapeutics. 6:257-261, 1999.
-
Wolf, M. E., Ranade, V., Molnar, J., Somberg, J. and Mosnaim, A. D.: Hypercalcemia,
arrhythmia and mood stabilizers. J. Clin. Psychopharmacology. 20(2):260-264,
2000.
-
Puente, J., Blanco, B., Montoya, M., Miranda, D., Contreras, I., Vinés E., Wolf, M.E. andMosnaim, A.D.: Effect of S. Typhi
wild type and O-antigen mutants on human natural killer cell activity. Intern.
J. Clin. Immunology. 355-364, 2000.
-
Mosnaim, A. D., Wolf, M. E.,
Tao, D.N., Puente, J., Freitag, and Diamond, S.: Degradation kinetics of
leucine-enkephalin by plasma samples from healthy controls and various patient
populations. In vitro drug effects. American J. Therapeutics. 7:185-194, 2000.
-
Puente, J., Blanco, L., Carrasco, C., Miranda, D., Wolf, M.E. and Mosnaim, A.D.: Effect of
Salmonella-infected human monocytes on natural killer cell cytotoxicity. In
vitro studies. International Immunopharmacology. 1:1285-1293, 2001.
-
Miranda, D., Puente, J., Blanco, L., Jara, P., Wolf, M.E. and Mosnaim, A.D.: Human natural
killer cell lysis of Salmonella typhi intracellularly-infected U 937 cells.
Res. Commun. Molec. Pathol. Pharmacology . 111:3-12, 2002.
-
Mosnaim, A.D.: Invited
editorial. Cephalalgia 22(7): 614-615, 2002.
-
Mosnaim, A. D., Puente, J.,
Saavedra, R., Diamond, S. and Wolf, M.: In vitro human plasma
leucine-enkephalin degradation is inhibited by a select number of drugs with
the phenothiazine molecule in their chemical structure. Pharmacology. Intern J
Experim and Clin Pharmacology. 67(1):6-13, 2003.
-
Miranda, D., Puente, J., Blanco, L., Jara, P., Wolf, M.E. and Mosnaim, A.D.: Lysis of
Salmonella typhi intracellularly-infected U.937 cells by human natural killer
cells. Effect of protein kinase inhibitors. American J. Therapeutics. 10:32-39,
2003.
-
Kettlun, A.M., Collados, C., García, L., Cartier, L.A., Wolf, M.E., Mosnaim, A.D. and Valenzuela,
M.A.: Matrix metalloproteinases profile in patients with Creuztfeldt-Jakob
Disease. International Journal of Clinical Practice. 57(6):475-478, 2003.
-
Mosnaim, A.D., Puente,
J., Hoang, C., Ranade, V. and Wolf, M.E.: Inhibition of human plasma
leucine-enkephalin aminopeptidase hydrolysis by various endogenous peptides and
a select number of clinically used drugs. American J. of Therapeutics.
11:459-465, 2004.
-
Valenzuela, M.A., Cartier, L.A., Mosnaim, A.D., Wolf, M.E., Ketllun, A.M., Collados, C. and
Garcia, L.: Proteinases and Prion Diseases, in Proteases in the Brain (U.
Lendeckel and N. Hooper, eds). Springer, USA, pp. 179-202, 2005.
-
Mosnaim, A.D., Ranade, V.R., Wolf, M.E., Puente, J. and Valenzuela, M.A.:
Phenothiazine molecule provides the basic chemical structure for various
classes of pharmacotherapeutic agents. American J. Therapeutics. 13:261-273,
2006.
-
Puente, J., Mosnaim, A.D. and
Wolf, M.: Stress, Opioid Peptides and the Immune Response, in Stress, Cytokines
and the Immune Response (N. P. Plotnikoff, R.E. Faith, A.J. Murgo and R.A.
Good, eds). CRC Press, Taylor & Francis Group, New York,
pp.125-142, 2006.
-
Mosnaim, A.D., Nguyen,
T.D., Tse, R, Puente, J., Couceyro, P. and Wolf, M.E.: In vitro
methionine-enkephalin degradation kinetics by human brain preparations.
Neurochemical Research. 33(1):81-86, 2008.
-
Mosnaim, A.D., Nguyen, T.D., Puente, J. and Wolf,, M.E.: Degradation kinetics of methionine5-enkephalin by
select brain areas from patients with chronic schizophrenia. American J. Therapeutics. 15(2):126-130, 2008.
-
Puente, J., Jaque, M.P., Carrasco, C., Cruz, C., Valenzuela, M.A., Wolf, M.E. and Mosnaim A.D.: Triptan
drugs, natural killer cell
cytotoxicity and neutrophils pro-matrix metalloproteinase-9 secretion. Headache. 40(10): 1482-1489, 2008.
-
Mosnaim, A.D., Saavedra, R. and Wolf, M.E.: Bacitracin-sensitive
aminopeptidase(s) degradation of methionine-enkephalin by human brain putamen
and hippocampus preparations. Inhibition by phenothiazine drugs. American J.
Therapeutics. 16:512-516, 2009.
-
Mosnaim, A.D., Abiola, R., Wolf, M.E. and Perlmuter,
L.C.: Etiology and risk factors for developing orthostatic hypotension.
American J. Therapeutics. 17(1):86-91, 2010.
-
Mosnaim, A.D., Puente, J. and Wolf, M.E.: Biological
correlates of migraine and cluster headaches: an overview of their potential
use in diagnosis and treatment. Pragmatic and Observational Research. 1:25-32,
2010.
-
Mosnaim, A.D., FuCheng, C. and Wolf, M.E.: Degradation
kinetics of methionine-enkephalin by human cerebrospinal fluid. In vitro
studies. American J. Therapeutics. 18:9-13, 2011.
-
Perlmuter, L.C., Sarda, G., Casavant, V., O’Hara,
K.,Hindes, M., Knott, PT. and Mosnaim,
A.D.: A review of orthostatic blood pressure regulation and
its association with mood and cognition. Clinical Autonomic Research.
22(2):99-107, 2012.
-
Mosnaim, A.D., Maturana, P, Puente, J. and Wolf, M.E.: Decreased
plasma methionine-enkephalin levels in cluster headache patients. American J.
Therapeutics. 19(3):174-179, 2012.
-
Mosnaim, A.D., Callaghan, O.H., Hudzik, T. and Wolf, M.E.: Rat
brain-uptake index for phenylethylamine and various monomethylated derivatives.
Neurochemical Research 38(4):842-846, 2013. PMID: 23389662.
-
Perlmuter, L.C, Sarda, G, Casavant, V. and Mosnaim A.D.: A review of the
etiology, associated comorbidities, and treatment of orthostatic hypotension. American
J. Therapeutics.20(3):279-291, 2013. PMID: 23656967.
-
Mosnaim, A.D., Maturana, P., Callaghan, O.H. and Wolf, M.E.:
Changes in plasma methionine-enkephalin levels associated with a cluster
headache episode. American J. Therapeutics. 20(5):463-468, 2013. PMID:
23353772.
-
Mosnaim, A.D., Hudzik, T. and Wolf, M.E.: Analgesic effects of
β-phenylethylamine and various methylated derivatives in mice. Neurochem
Res. 39(9):1675-80, 2014. DOI: 10.1007/s11064-014-1354-7.
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Mosnaim, A.D. and Wolf, M.E. (eds.):
Non-catecholic Phenylethylamines. Part 1: Phenylethylamine: Biological
Mechanisms and Clinical Aspects. Marcel Dekker, Inc., New York, 1978.
-
Mosnaim, A.D. and Wolf, M.E. (eds.):
Non-catecholic Phenylethylamines. Part 2: Phenylethanolamine, Tyramines and
Octopamine. Marcel Dekker, Inc., New York, 1980.
-
Wolf, M.E. and Mosnaim,
A.D. (eds.): Tardive Dyskinesia: Biological Mechanisms and Clinical
Aspects. American Psychiatric Press, Washington, DC 1988.
-
Wolf, M.E. and Mosnaim,
A.D. (eds.): Post Traumatic Stress Disorder: Etiology,
Phenomenology and Treatment. American Psychiatric Press, Washington, DC 1990.