Prof. Jolanta Dorszewska

Laboratory of Neurobiology, Department of Neurology,

Poznan University of Medical Sciences, Poznan, Poland

Professor

Chief of Laboratory of Neurobiology

Email: dorszewskaj@yahoo.com

Qualifications

1996 Ph.D., Poznan University of Medical Sciences, Poznan, Poland, Neurochemistry

1987 M.Sc., Poznan University of Medical Sciences, Poznan, Poland, Pharmacy

Publications (Selected)

1. Dorszewska J., Oczkowska A., Suwalska M., Rozycka A., Florczak-Wyspianska J., Dezor M., Lianeri M., Jagodzinski P.P., Kowalczyk M.J., Prendecki M., Kozubski W. (2014), Mutations in the exon 7 of Trp53 gene and the level of p53 protein in double transgenic mouse model of Alzheimer’s disease, Folia Neuropathol., 52, 30-40.
2. Dorszewska J., Różycka A., Oczkowska A., Florczak-Wyspiańska J., Prendecki M., Dezor M., Postrach I., Jagodziński P.P., Kozubski W. (2014), Mutations of TP53 gene and oxidative stress in Alzheimer’s disease patients, Adv. Alzheimers Dis., 3, 24-32.
3. Owecki M., Dorszewska J., Sawicka-Gutaj N., Oczkowska A., Owecki M.K., Michalak M., Fischbach J., Kozubski W., Ruchala M. (2014), Serum homocysteine levels are decreased in levothyroxine-treated women with autoimmune thyroiditis, BMC Endocr Disord., 14, 18, (1-6).
4. Permoda-Osip A., Dorszewska J., Rybakowski J. (2014), The concentration of homocysteine and treatment of depression in affective disorders, Farmakoter. Psychiat. Neurol., 30, 1, 15-20.
5. Dorszewska J., Prandecki M., Lianeri M., Kozubski W. (2014), Molecular effects of L-dopa therapy in Parkinson’s disease, Curr. Genomics, 2014, 15, 1, 11-17.
6. Oczkowska A., Kozubski W., Lianeri M., Dorszewska J. (2014), Genetic variants in diseases of the extrapyramidal system, Curr. Genomics, 15, 1, 18-27.
7. Oczkowska A., Lianeri M., Kozubski W., Dorszewska J. (2014), Mutations of PARK Genes and Alpha-synuclein, and Parkin Levels, A Synopsis of Parkinson's Disease, Abdul Qayyum Rana (Ed.), ISBN 978-953-51-1229-7, InTech, 1-38.
8. Lagan-Jedrzejczyk U., Lianeri U., Kozubski W., Dorszewska J. (2014), Homocysteine and apoptotic factors in epileptic patients treated with antiepileptic drugs. Homocysteine: structure, biosynthesis and health implications, Kilmer McCully (Ed.), ISBN: 078-1-62948-639-0, NOVA Sciences Publishers, Inc, NY, USA, 83-111.
9. Permoda-Osip A., Dorszewska J., Skibinska M., Chlopocka-Wozniak M., Robakowski J.K. (2013), Hyperhomocysteinemia in bipolar depression: clinical and biochemical correlates, Neuropsychobiology, 68, 193–196.
10. Karolczak D., Sawicka E., Dorszewska J., Radel A., Bodnar M., Błaszczyk A., Jagielska J., Marszałek A. (2013), Memantine - neuroprotective drug in aging brain, Pol. J. Pathol., 64, 3, 196-203.
11. Rozycka A., Dorszewska J., Steinborn B., Lianeri M., Winczewska-Wiktor A., Sniezawska A., Wisniewska K., Jagodzinski P.P. (2013), Association Study of the 2-bp Deletion Polymorphism in Exon 6 of the CHRFAM7A Gene with Idiopathic Generalized Epilepsy, DNA Cell Biol., 32, 11, 640-647.
12. Permoda-Osip A., Dorszewska J., Bartkowska-Sniatkowska A., Chlopocka-Wozniak M., Robakowski J.K. (2013), Vitamin B12 level May be related to the efficacy of single ketamine infusion in bipolar depression, Pharmacopsychiatry, 46, 227-228.
13. Dorszewska Jolanta and Kozubski Wojciech (2013). Methionine, homocysteine and cysteine, and antiepileptic drugs in epilepsy. Methionine: Biosynthesis, Chemical Structure and Toxicity, Alexander Snegursky (Ed.), ISBN: 978-1-62618-292-9, NOVA Sciences Publishers, Inc, NY, USA, 155-175.
14. Dorszewska J. (2013), Cell biology of normal brain aging: Synaptic plasticity - Cell death. Aging Clin. Exp. Res., 25, 1, 25-34.
15. Różycka A., Dorszewska J., Steinborn B., Kempisty B., Lianeri M., Wiśniewska K., Jagodziński P.P. (2013), A transcript coding for a partially duplicated form of α7 nicotinic acetylcholine receptor is absent from the CD4+ T-lymphocytes of patients with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), Folia Neuropathol., 51, 1, 65-75.
16. Dorszewska J., Florczak-Wyspiańska J., Oczkowska A., Dezor M., Prendecki M., Kozubski W. (2013), Homocysteine and asymmetric dimethylarginine concentrations in the plasma of Alzheimer's disease patients with varying degrees of dementia, Adv. Alzheimers Dis., 1, 1-6.
17. Dorszewska Jolanta and Kozubski Wojciech (2011). Oxidative DNA Damage and the Level of Biothiols, and L-Dopa Therapy in Parkinson’s Disease, Etiology and Pathophysiology of Parkinson's Disease, Abdul Qayyum Rana (Ed.), ISBN: 978-953-307-462-7, InTech.
18. Sniezawska A., Dorszewska J., Rozycka A., Przedpelska-Ober E., Lianeri M., Jagodzinski P.P, Kozubski W. (2011), MTHFR, MTR, and MTHFD1 gene polymorphisms compared to homocysteine and asymmetric dimethylarginine concentrations and their metabolites in epileptic patients treated with antiepileptic drugs, Seizure, 20, 533-540.
19. Dezor M., Dorszewska J., Florczak J., Kempisty B., Jaroszewska-Kolecka J., Rozycka A., Polrolniczak A., Bugaj R., Jagodzinski P.P., Kozubski W. (2011), Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-alpha proteins in peripheral lymphocytes of patients with Alzheimer’s disease, Folia Neuropathol., 49, 123-131.
20. Dorszewska J., Kempisty B., Jaroszewska-Kolecka J., Rózycka A., Florczak J., Lianeri M., Jagodziński P.P., Kozubski W. (2009), Expression and polymorphisms of gene 8-oxoguanine glycosylase 1 and the level of oxidative DNA damage in peripheral blood lymphocytes of patients with Alzheimer's disease, DNA Cell Biol., 28, 11, 579-588.
21. Kaźmierski R., Watała C., Podsiadły E., Dorszewska J., Kozubski W. (2009), Association of atherosclerotic risk factors with carotid adventitial thickness assessed by ultrasonography, J. Clin. Ultrasound, 37, 6, 333-341.
22. Dorszewska J., Florczak J., Różycka A., Kempisty B., Jaroszewska-Kolecka J., Chojnacka K., Trzeciak W.H., Kozubski W. (2007), Oxidative DNA damage and level of thiols as related to polymorphism of MTHFR, MTR, MTHFD1 in Alzheimer's and Parkinson's disease, Acta Neurobiol. Exp., 67, 113-129.
23. Dorszewska J., Florczak J., Różycka A., Jaroszewska-Kolecka J., Trzeciak W.H., Kozubski W. (2005), Polymorphisms of the CHRNA4 gene encoding the α subunit of nicotinic acetylcholine receptor as related to the oxidative DNA damage and the level of apoptotic proteins in lymphocytes of the patients with Alzheimer's disease, DNA Cell Biol., 24, 12, 786-794.
24. Dorszewska J., Adamczewska-Goncerzewicz Z. (2004), Oxidative damage to DNA, p53 gene expression and p53 protein level in the process of aging in rat brain, Respir. Physiol. Neurobiol., 139, 227-236.
25. Dorszewska J., Adamczewska-Goncerzewicz Z., Szczech J. (2004), Apoptotic proteins in the course of aging of central nervous system in the rat, Respir. Physiol. Neurobiol., 139, 145-155.

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Last Updated: September, 2014.