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Biography

Prof. Ajith Siriwardena

University of Manchester, UK


Email: Ajith.Siriwardena@cmft.nhs.uk


Qualifications


1991 M.D., University of Manchester


Publications (selected)

  1. Conway AM, Partington R, Jones DRT, Siriwardena AK, Sheen AJ. A re-audit of adherence to local guidelines for antibiotic prescribing in the department of General Surgery. Presented at the annual meeting of the Association of Surgeons of Great Britain and Ireland, Glasgow, May 19th 2009.
  2. Shah N, Siriwardena AK. Long-term outcome of elective surgery in chronic pancreatitis.  Presented at the annual meeting of the Association of Surgeons of Great Britain and Ireland (ASGBI), Glasgow May 20th 2009.
  3. Babu BI, Malleo G, Genovese T, Di Paola R, Siriwardena AK, Cuzzocrea S. Green Tea Polyphenol ameliorates pancreatic injury in experimental acute pancreatitis. Presented at the 8th Congress of the European Hepato-Biliary Association (EHPBA June 20th 2009, Athens, Greece).
  4. Jegatheeswaran S, Sheen AJ, Siriwardena AK. Guidance for development of a high-quality surgical service for hilar cholangiocarcinoma in a regional hepatobiliary surgical service. Presented at the 8th Congress of the European Hepato-Biliary Association (EHPBA June 18th 2009, Athens, Greece).
  5. Oliveira-Cunha M, Sheen AJ, Siriwardena AK, Byers RJ. Poly (A) cDNA real-time PCR in pancreatic ductal juice in patients undergoing pancreaticoduodenectomy. Presented at the 8th Congress of the European Hepato-Biliary Association (EHPBA June 18th 2009, Athens, Greece).
  6. Junejo M, Sheen AJ, Siriwardena AK. Towards a no-laparoscopy staging algorithm for patients undergoing pancreaticoduodenectomy. Presented at the 8th Congress of the European Hepato-Biliary Association (EHPBA June 20th 2009, Athens, Greece).
  7. Henley N, Reid F, Petras P, Hill J, Siriwardena AK, Watson AJ, Sheen AJ. Synchronous hepatectomy and colon resection for colorectal cancer co-presenting with hepatic metastases. Presented at the 8th Congress of the European Hepato-Biliary Association (EHPBA June 20th 2009, Athens, Greece).
  8. Shah N, Siriwardena AK. Long-term outcome of surgical intervention for chronic pancreatitis. Presented at the 8th Congress of the European Hepato-Biliary Association (EHPBA June 20th 2009, Athens, Greece).
  9. Jegatheeswaran S, Sheen AJ, Siriwardena AK. Development of a surgical service for hilar cholangiocarcinoma in a regional hepatobiliary surgical service. Presented at the Annual meeting of the Association of Upper GI Surgeons of Great Britain and Ireland (AUGIS), Nottingham, September 3rd 2009.
  10. Jegatheeswaran S, Sheen AJ, Siriwardena AK. Co-localisation of a High-volume liver surgery service is beneficial for pancreatic cancer surgery: towards optimal designation of HPB centres.  Presented at the Annual meeting of the Association of Upper GI Surgeons of Great Britain and Ireland (AUGIS), Nottingham, September 3rd  2009.
  11. Bandara I, Henley N, Al-Himdani R, Siriwardena AK, Sheen AJ. Within-service pathways facilitate urgent laparoscopic cholecystectomy by specialist HPB surgeons without recourse to parallel upper GI/ colorectal rotas. Presented at the Annual meeting of the Association of Upper GI Surgeons of Great Britain and Ireland (AUGIS), Nottingham, September 4th 2009.
  12. Mason JM, Balachandra S, Babu BI, Bagul A, Siriwardena AK. An exploratory phase diagnostic study of organ dysfunction score performance for the prediction of severity in acute pancreatitis. Presented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 4th November 2009.
  13. Oliveira-Cunha M, Sheen AJ, Byers R, Siriwardena AK. Poly (A) cDNA real-time PCR in pancreatic ductal juice in patients undergoing pancreaticoduodenectomy. Presented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 4th November 2009.
  14. Shah NS, Siriwardena AK. Quality of life indices assessed by EORTC QLQ C-30 and PAN 28 questionnaire: comparison of a disease duration matched cohort of patients with chronic pancreatitis taking antox to a non-antox CP group. Presented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 5th November 2009.
  15. Oliveira-Cunha M, Siriwardena AK, Newman W. EGFR mutation in pancreatic and peri-ampullary cancer. Prsented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 5th November 2009.
  16. Babu BI, Jamdar S, Siriwardena AK, Jeziorska M. Effect of activated protein C on apoptotic pathways in experimental acute pancreatitis. Presented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 6th November 2009.
  17. Babu BI, Genovese T, Mazzon E, Crissafulli C, Siriwardena AK. Cuzzocrea S. Human recombinant activated protein C (xigris) attenuates cerulein-induced experimental acute pancreatitis. Presented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 6th November 2009.
  18. Babu BI, Sheen AJ, Siriwardena AK. Protein C dynamics in clinical acute pancreatitis. Presented at the special meeting to mark the 40th Anniversaries of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, Hawaii, 7th November 2009.
  19. Shah N, Makin AJ, Sheen A, Siriwardena AK. Formal assessment of quality of life using validated EORTC questionnaires in patients taking Antox™ for painful chronic pancreatitis: comparison to a disease-duration matched cohort. Presented at the United European Gastroenterology Week, London 25th November 2009.
  20. Oliveira-Cunha M, Sheen AJ, Byers R, Siriwardena AK. RNA analysis of pancreatic ductal juice by poly (a) cDNA real-time pcr during pancreaticoduodenectomy. Presented at the annual meeting of the Pancreatic  Society of Gt Britain & Ireland, 4th December 2009. Awarded “top 3 posters at the meeting” award.
  21. Oliveira-Cunha M, Siriwardena AK, Newman W. Mutational status of EGFR and K-RAS in pancreatic and peri-ampullary cancer. Accepted for presentation at the annual meeting of the Pancreatic Society of Gt Britain & Ireland, 4th December 2009.
  22. Babu BI, Genovese T, Mazzon E, Crissafulli C, Siriwardena AK, Cuzzocrea S. Human recombinant activated protein C (xigris) attenuates cerulein-induced experimental acute pancreatitis via Nf-kB and apoptotic pathways. Presented in the Patey prize session of the Society of Academic and Research Surgeons, Royal Free Hospital, 6th January 2010, London, England.
  23. Malde D, Siriwardena AK, Sheen AJ. Laparoscopic Floseal® haemostatic matrix as an aid to haemostasis during parenchymal transection in laparoscopic hepatectomy. Submitted for video presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  24. Babu BI, Siriwardena AK. Functional Protein C levels early in the disease course of acute pancreatitis. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  25. Petras P, Sheen AJ, Siriwardena AK. Co-localization of liver and pancreas cancer surgery is beneficial for outcome: towards optimal configuration of HPB services. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  26. Babu BI, Genovese T, Mazzon E, Siriwardena AK. Cuzzocrea S. Human recombinant activated protein C (xigris) attenuates experimental acute pancreatitis via modulation of Nf-kB and apoptotic pathways. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  27. Junejo M, Sheen AJ, Moores J, Foster P, Atkinson D, Parker MJ & Siriwardena AK.  Cardiopulmonary exercise testing (CPX) for the pre-operative assessment of risk in patients undergoing hepatic resection. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  28. Oliveira-Cunha M, Siriwardena AK, Newman W. EGFR and KRAS mutational analysis and their correlation to survival in pancreatic and peri-ampullary cancer. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  29. Oliveira-Cunha M, Sheen AJ, Byers RJ, Siriwardena AK. Gene expression in pancreatic ductal juice and matched tissue in patients undergoing pancreaticoduodenectomy. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.
  30. Oliveira-Cunha M, Sheen AJ, Byers RJ, Siriwardena AK. Utilizing poly-(A)-RT-PCR to evaluate indicator genes in pancreatic and peri-ampullary cancer. Submitted for presentation at the 9th World congress of the International HepatoPancreatoBiliary Association, Buenos Aires, Argentina, April 18th-22nd 2010.