Dr. Oreste Gualillo

SERGAS, Santiago University Clinical Hospital, Spain

Email: oreste.gualillo@sergas.es

Qualifications

1996  Ph.D., Department of Experimental Pharmacology, University of Naples “Federico II”, Italy

1991  Pharm.D., Department of Department of Experimental Pharmacology, University of Naples “Federico II”, Italy

Publications (selected)

1. González-Rodríguez, María & Ait Eldjoudi, Djedjiga & Cordero‐Barreal, Alfonso & Farrag, Mariam & Varela‐García, María & Torrijos‐Pulpón, Carlos & Lago, Francisca & García‐Caballero, Lucía & Farrag, Yousof & Conde Aranda, Javier & Pino, Jesús & Gualillo, Oreste. (2025). E74‐like ETS transcription factor 3 expression and regulation in human intervertebral disc. JOR Spine. 8. 10.1002/jsp2.70016.

2. Comella, Federica & Aragón Herrera, Alana & Pirozzi, Claudio & Feijóo-Bandín, Sandra & Lama, Adriano & Opallo, Nicola & Melini, Stefania & Del Piano, Filomena & Gualillo, Oreste & Meli, Rosaria & Mattace Raso, Giuseppina & Lago, Francisca. (2024). Oleoylethanolamide mitigates cardiometabolic disruption secondary to obesity induced by high-fat diet in mice. Life Sciences. 359. 123226. 10.1016/j.lfs.2024.123226.

3. López, Miguel & Gualillo, Oreste. (2024). Rheumatic diseases and metabolism: where centre and periphery meet. Nature Reviews Rheumatology. 20. 10.1038/s41584-024-01178-6.

4. Farrag, Mariam & Cordero-Barreal, Alfonso & Ait Eldjoudi, Djedjiga & Varela-García, María & Pulpón, Carlos & Lago, Francisca & Essawy, Amina & Soffar, Ahmed & Pino, Jesús & Farrag, Yousof & Gualillo, Oreste. (2024). Impact of Chondrocyte Inflammation on Glial Cell Activation: The Mediating Role of Nitric Oxide. Cartilage. 19476035241292323. 10.1177/19476035241292323.

5. Conde Aranda, Javier & Scotece, Morena & Varela-García, María & Torrijos-Pulpón, Carlos & Arosa, Laura & Camba-Gómez, Miguel & Pino, Jesús & Gualillo, Oreste. (2024). Lipocalin-2 Serum Levels in Rheumatoid Arthritis Patients Treated with Adalimumab and Its Correlation with Proinflammatory Factors. Mediators of Inflammation. 2024. 10.1155/2024/7264704.

6. Varela-García, María & Torrijos-Pulpón, Carlos & Pino-López, Laura & Farrag, Yousof & Forneiro-Pérez, Rocío & Conde Aranda, Javier & Gualillo, Oreste & Pino, Jesús. (2024). A retrospective study describing the acetabular consequences of Legg- Calve-Perthes disease. BMC Musculoskeletal Disorders. 25. 10.1186/s12891-024-07852-w.

7. Moncada, Danny & Bouza, Rebeca & Rico, Maite & Rodríguez-Llamazares, Saddys & Pettinelli, Natalia & Aragón Herrera, Alana & Feijóo-Bandín, Sandra & Gualillo, Oreste & Lago, Francisca & Farrag, Yousof & Salavagione, Horacio. (2024). Injectable Carrageenan/Green Graphene Oxide Hydrogel: A Comprehensive Analysis of Mechanical, Rheological, and Biocompatibility Properties. Polymers. 16. 2345. 10.3390/polym16162345.

8. Farrag, Yousof & Farrag, Mariam & Varela-García, María & Pulpón, Carlos & Capuozzo, Maurizio & Ottaiano, Alessando & Lago, Francisca & Mera, Antonio & Pino, Jesús & Gualillo, Oreste. (2024). Adipokines as potential pharmacological targets for immune inflammatory rheumatic diseases: Focus on rheumatoid arthritis, osteoarthritis, and intervertebral disc degeneration. Pharmacological Research. 205. 107219. 10.1016/j.phrs.2024.107219.

9. Pirozzi, Claudio & Melini, Stefania & Comella, F. & Aragón Herrera, Alana & Lama, Adriano & Farrag, Yousof & Mattace Raso, Giuseppina & Gualillo, Oreste & Paz, F. & Meli, Rosaria. (2024). Novel insights into the effect of SGLT-2 inhibitor empagliflozin on hepatic damage in diabetic obese Zucker rats. Digestive and Liver Disease. 56. S13. 10.1016/j.dld.2024.01.021.

10. Gómez, M & Arosa, L & Ait Eldjoudi, Djedjiga & González-Rodríguez, María & Gualillo, Oreste & Conde Aranda, Javier. (2024). P084 Natural extracts and omega-3 derived molecule: role in resolution of intestinal inflammation. Journal of Crohn's and Colitis. 18. i359-i359. 10.1093/ecco-jcc/jjad212.0214.

11. Varela-García, María & Torrijos-Pulpón, Carlos & Pino-López, Laura & Farrag, Yousof & Forneiro-Pérez, Rocío & Conde Aranda, Javier & Gualillo, Oreste & Pino, Jesús. (2024). Legg Calve Perthes disease: a retrospective study of pelvic radiographic parameters. 10.21203/rs.3.rs-3865841/v1.

12. Santorsola, Mariachiara & Capuozzo, Maurizio & Nasti, Guglielmo & Sabbatino, Francesco & Di Mauro, Annabella & Mauro, Giordana & Vanni, Gianluca & Maiolino, Piera & Correra, Marco & Granata, Vincenza & Gualillo, Oreste & Berretta, Massimiliano & Ottaiano, Alessandro. (2024). Exploring the Spectrum of VEGF Inhibitors’ Toxicities from Systemic to Intra-Vitreal Usage in Medical Practice. Cancers. 16. 350. 10.3390/cancers16020350.

13. Ait Eldjoudi, Djedjiga & González-Rodríguez, María & Barreal, A.C. & Farrag, Yousof & Mobasheri, Ali & Pino, Jesús & Sakai, Daisuke & Gualillo, Oreste. (2024). FUNCTIONAL ACTIVITY OF MONOMERIC C-REACTIVE PROTEIN IN INTERVERTEBRAL DISC. Orthopaedic Proceedings. 106-B. 141-141. 10.1302/1358-992X.2024.2.141.

14. González-Rodríguez, María & Ait Eldjoudi, Djedjiga & Cordero-Barreal, Alfonso & Farrag, Mariam & Varela-García, María & Torrijos-Pulpón, Carlos & Capuozzo, Maurizio & Ottaiano, Alessandro & Lago, Francisca & Pino, Jesús & Farrag, Yousof & Gualillo, Oreste. (2023). Oleocanthal, an Antioxidant Phenolic Compound in Extra Virgin Olive Oil (EVOO): A Comprehensive Systematic Review of Its Potential in Inflammation and Cancer. Antioxidants. 12. 2112. 10.3390/antiox12122112.

15. Farrag, Yousof & Ait Eldjoudi, Djedjiga & Farrag, Mariam & González-Rodríguez, María & Cordero, Alfonso & Varela-García, María & Pulpón, Carlos & Bouza, Rebeca & Lago, Francisca & Pino, Jesús & Alvarez-Lorenzo, Carmen & Gualillo, Oreste. (2023). Poly(ethylene Glycol) Methyl Ether Methacrylate-Based Injectable Hydrogels: Swelling, Rheological, and In Vitro Biocompatibility Properties with ATDC5 Chondrogenic Lineage. Polymers. 15. 4635. 10.3390/polym15244635.

16. Aragón Herrera, Alana & Feijóo-Bandín, Sandra & Anido-Varela, Laura & Vázquez-Abuín, Xocas & Moraña Fernández, Sandra & Tarazón, Estefanía & Roselló-Lletí, Esther & Portoles, Manuel & García-Seara, Javier & Seijas, José & Rodríguez-Penas, Diego & Bani, Daniele & Gualillo, Oreste & González-Juanatey, José & Lago, Francisca. (2023). 5. EL FÁRMACO CARDIOPROTECTOR SERELAXINA REGULA EL LIPIDOMA, EL METABOLISMO LIPÍDICO Y EL PERFIL INFLAMATORIO EN TEJIDO ADIPOSO VISCERAL DE RATA. Revista Española de Cardiología. 76. 821-822. 10.1016/S0300-8932(24)01262-4.

17. Ottaiano, Alessandro & Santorsola, Mariachiara & Circelli, Luisa & Ianniello, Monica & Casillo, Marika & Petrillo, Nadia & Sabbatino, Francesco & Cascella, Marco & Perri, Francesco & Capuozzo, Maurizio & Albino, Vittorio & Granata, Vincenza & Izzo, Francesco & Di Mauro, Annabella & Berretta, Massimiliano & Ruggiero, Raffaella & Gualillo, Oreste & Sirica, Roberto & Nasti, Guglielmo & Savarese, Giovanni. (2023). BRAF p.V600E mutation as a molecular boundary between genuine oligo-repeated and poly-metastatic disease in colorectal cancer. Neoplasia (New York, N.Y.). 44. 100930. 10.1016/j.neo.2023.100930.

18. Francisco, Vera & Ait Eldjoudi, Djedjiga & González-Rodríguez, María & Cordero-Barreal, Alfonso & Marques, Patrice & Sanz, Maria & Real, José & Lago, Francisca & Pino, Jesús & Farrag, Yousof & Gualillo, Oreste. (2023). Metabolomic signature and molecular profile of normal and degenerated human intervertebral disc cells. The Spine Journal. 23. 10.1016/j.spinee.2023.06.005.

19. Schol, Jordy & Tamagawa, Shota & Ambrosio, Luca & Soma, Hazuki & Gualillo, Oreste & Sakai, Daisuke. (2023). Study of the effect of adipose tissue dysfunction in IVDD.

20. Ottaiano, Alessandro & Santorsola, Mariachiara & Capuozzo, Maurizio & Perri, Francesco & Circelli, Luisa & Cascella, Marco & Ianniello, Monica & Sabbatino, Francesco & Granata, Vincenza & Izzo, Francesco & Iervolino, Domenico & Casillo, Marika & Petrillo, Nadia & Gualillo, Oreste & Nasti, Guglielmo & Savarese, Giovanni. (2023). The prognostic role of p53 mutations in metastatic colorectal cancer: A systematic review and meta-analysis. Critical Reviews in Oncology/Hematology. 186. 104018. 10.1016/j.critrevonc.2023.104018.

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