Prof. Andrei Surguchov
VA Medical Center and Kansas University Medical Center
Research Biologist
Email: asurguchov@kumc.edu
Qualifications
1976 Ph.D., Cardiology Research Center, Molecular Biology
1970 M.S., Moscow State University, Molecular Biology
1968 B.S., Moscow State University, Biochemistry
Publications (selected)
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Pronin AN, Morris AJ, Surguchov A, Benovic JL. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem. 2000, 275, 26515-26522
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A. Surguchov, B. McMahon, E. Masliah, I. Surgucheva. Synucleins in ocular tissues. 2001, J Neurosci Res, 65, 68-77
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A. Surguchov, RE. Palazzo, and I. Surgucheva. Gamma synucleins: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motility and Cytoskeleton, 2001, 49, 218-228
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Surgucheva I., McMahan B, F. Ahmed, Tomarev S, Wax MB, Surguchov A. 2002. Synucleins in glaucoma. J Neurosci Res, 68: 97-106.
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Surgucheva I, Sivak, JM, Fini ME, Palazzo RE and Surguchov AP. 2003. Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells. Arch Biochem Biophys. 410: 167-176.
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Maurage CA, Ruchoux MM, De Vos R, Surguchov A, Destee A. 2003. Retinal involvement in dementia with Lewy bodies: A clue to hallucinations? Ann Neurol. 54(4): 542-7.
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Snyder HM, Mensah K, Surgucheva I, Festoff B, Surguchov A, Wolozin B. Synuclein prevents Proteasomal inhibition by α-synuclein but not γ-synuclein. J Biol Chem, 2005. 4; 280: 7562-9.
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Surgucheva, B. Yue, BC Park, S Tomarev and A. Surguchov. 2005. Interaction of myocilin with gamma- synuclein and its role in neurodegeneration in glaucoma. Cellular Molecular Neurobiology, 25 ,6, 1009-1033.
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Surgucheva I, Ninkina N, Buchman VL, Grasing K, A. Surguchov. 2005. Protein aggregation in retinal cells and approaches to cell protection. Cellular Molecular Neurobiology, 25, 6, 1051-1066. PMID: 16392036
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A. Surguchov. 2008. Molecular and cellular biology of synucleins. International Review of Cell and Molecular Biology, 270, 225-317. PMID: 19081538
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A. Surguchev and A. Surguchov. 2010. Conformational Diseases: Looking into the eyes. Brain Research Bulletin, 81, pp. 12-24. PMID: 19808079
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Surgucheva I, Chidambaram K, Willoughby DA, Surguchov A. MicroRNA regulates MMP-9 expression. J Ocular Biology, Diseases and Bioinformatics 2010; 3: 41-52, PMID: 21818406
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Surgucheva I, McMahon B, Surguchov A. Patterns of synuclein expression throughout lens development. J Biophys Chem 2010;1:12-18. DOI: 10.4236/jbpc.2010.11002
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Surguchov A. in “Protein Aggregation” (Editor: Douglas A. Stein). Folding and unfolding of Synucleins, Nova Science Publishers, 2011. ISBN: 978-1-61761-815-4
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Surgucheva I and Surguchov A. Expression of caveolins in trabecular meshwork cells and its possible implication in pathogenesis of primary open angle glaucoma. Molecular Vision 2011; 17: 2878-2888. PMID: 22128235
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Surgucheva I, Sharov VS, Surguchov A. γ-Synuclein: seeding of α-synuclein aggregation and transmission between cells. Biochemistry. 2012, 51 (23): 4743-54.
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Surguchov A. Synucleins : Are they two edged swords? J Neurosci Res, 2012
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