Dr. Suhe Wang
University of Michigan, USA
Research Assistant Professor

Email: shidasui@umich.edu

Qualifications

1996 Ph.D., University of Strathclyde, Department of Pharmaceutical Sciences

1985 MD., Fujian Medical University, School of Medicine

Publications (selected)

1. Wang SH, Carayanniotis GC, Zhang Y, Gupta M, McGregor A, Banga JP: Induction of thyroiditis in mice with thyrotropin receptor lacking serologically dominant regions.  Clin Exp Immunol 1998;113:627-633. PMC ID:  PMC1905011
2. Wang SH, Koenig RJ, Giordano T, Myc A, Thompson NW, Baker JR Jr.  1α, 25-dihydroxyvitamin D3 up-regulates Bcl-2 expression and induces protection from the induction of programmed cell death in normal thyrocytes.  Endocrinology 1999;140:1649-1656.
3. Wang SH, Myc A, Koenig RJ, Bretz JD, Arscott PL, Baker JR Jr.  2-methoxyestradiol, an endogenous estrogen metabolite, induces thyroid cell apoptosis.  Molecular and Cellular Endocrinology 2000;165:163-172.
4. Wang SH, Bretz JD, Phelps E, Mezosi E, Arscott PL, Utsugi S, Baker JR Jr. A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms non-destructive to destructive thyroiditis in experimental autoimmune thyroiditis.  J Immunology 2002;168:2470-2474.
5. Wang SH, Mezosi E, Wolf JM, Cao Z, Utsugi S Gauger PG, Doherty GM, Baker JR Jr.  IFNg sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by up-regulating Bak expression. Oncogene 2004;23:928-935
6. Wang SH, Cao Z, Wolf JM, Van Antwerp M, Baker JR Jr.  Death ligand TRAIL inhibits experimental autoimmune thyroiditis.  Endocrinology, 2005;146(11): 4721-4726.
7. Shi X, Wang SH, Chen X, Meshinchi S, Baker JR Jr.  Encapsulation of submicrometer-sized 2-methoxyestradiol crystals into polymer multilayer capsules for biological applications.  Molecular Pharmaceutics, 2006;3(2): 144-151.
8. Shi X, Wang SH, Sun H, Baker JR Jr.  Improved Biocompatibility of Dendrimer-Encapsulated Gold Nanoparticles.  Soft Matter, 2007;3:71-74.
9. Wang SH, Shi X, Van Antwerp M, Cao Z, Swanson SD, Bi  X, Baker JR Jr.  Dendrimer-Functionalized Iron Oxide Nanoparticles for Specific Targeting and Imaging of Cancer Cells.  Adv.  Func.  Mater. 2007;17:3043-3050.
10. Shi X, Wang SH, Meshinchi S, Van Antwerp M, Bi X, Lee I, Baker JR Jr. Dendrimer-Entrapped Gold Nanoparticles as a Platform for Cancer Cell Targeting and Imaging.  Small.  2007;3(7):1245-1252.
11. Wang SH, Van Antwerp M, Kuick R, Gauger PG, Doherty GM, Fan YY, Baker JR Jr.  Microarray analysis of cytokine activation of apoptosis pathways in the thyroid.  Endocrinology.  2007;148(10):4844-4852.
12. Shi X., Wang SH., Swanson, SD, Ge S, Cao Z, Van Antwerp M., Landmark KJ, Baker JR Jr.  Dendrimer-Functionalized Shell-Crosslinked Iron Oxide Nanoparticles for in vivo Magnetic Resonance Imaging of Tumors.  Adv.  Mater.  2008, 20.  1671-1678.  Rec’d 11/07;Rev’d 12/07
13. Wang SH, Koenig RJ: A locally secreted thyrotropin variant may regulate thyroid function in thyroid inflammatory disorders.  Thyroid, 2009;19(1):5-6.  PMID: 19119979
14. Wang SH*, Chen GH, Fan YY, Van Antwerp M, Baker JR Jr.  TRAIL inhibits experimental autoimmune thyroiditis by the expansion of CD4⁺CD25⁺ regulatory T cells.  Endocrinology.  2009;150 (4):2000-2007. PMC ID:  PMC2659286
15. Wang SH, Shi X, Chen X, Baker JR Jr.  Therapeutic Efficacy of 2-Methoxylestradiol Microcrystals Encapsulated within Polyelectrolyte Multilayer Capsules.  Macromolecular Bioscience, 2009, 9(5):429-436. PMID: 19370749  NIHMS212634
16. Shi X, Wang SH, Lee I, Shen M, Baker JR Jr.  Comparison of the internalization of targeted dendrimers and dendrimer-entrapped gold nanoparticles into cancer cells.  Biopolymers, 2009 91 (11):936-942. PMID: 19603491
17. Shi X, Wang SH, Shen M, Van Antwerp M, Chen X, Li C, Petersen EJ, Huang Q, Weber WJ, Baker JR Jr. Multifunctional Dendrimer-Modified Multiwalled Carbon Nanotubes: Synthesis, Characterization, and In Vitro Cancer Cell Targeting and Imaging.  Biomacromolecules.  2009;10(7):1744-1750.
18. Shen M, Wang SH, Shi X, Chen X, Huang Q, Petersen EJ, Pinto RA, Baker JR Jr., Weber WJ Jr. Polyethyleneimine-mediated functionalization of multi-walled carbon nanotubes: synthesis, characterization andin vitro toxicity assay.  J Phys Chem C 2009;113(8):3150-3156.
19. Shi X, Wang SH, Van Antwerp ME, Chen X, Baker JR Jr. Targeting and detecting cancer cells using spontaneously formed multifunctional dendrimer-stabilized gold nanoparticles. Analyst.2009 134 (7):1373-1379.  PMID: 19562204  NIHMS217922
20. Shi X, Lee I, Chen X, Shen M, Xiao S, Baker JR Jr., Wang SH*.  Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers.  Soft Matter, 2010;1(6):2539-2545.  PMCID: 2941193  NIHMS230335
21. Guo R, Yao Y, Cheng G, Wang SH, Li Y, Shen M, Zhang Y, Baker JR Jr.,Wang J, Shi X. Synthesis of glycoconjugated poly(amindoamine) dendrimers for targeting human liver cancer cells. RSC Advances, 2012, 2: 99-102.
22. Shen M, Cai H, Sun K, Li K, Wang X, Cao X, Wang S, Guo R, Zhang G, Wang SH*, and Shi X. Facile one-pot preparation, surface functionalization, and toxicity assay of APTS-coated iron oxide nanoparticles. Nanotechnology, Mar 16, 2012, 23 105601
23. Wang SH*, Fan YY, Makidon  PE, Cao Z, Baker JR Jr. Induction of immune tolerance in mice with a novel mucosal nanoemulsion adjuvant and self-antigen. Nanomedicine, Mar 15, 2012. [Epub ahead of print] PMID:  22420425.

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