Dr. Zhiwei Huang

National University of Singapore, Singapore

Email: biehzw@nus.edu.sg

Qualifications

1999 Ph.D., Nanyang Technological University

1990 M.Sc., Fujian Normal University

1987 B.Sc., Fujian Normal University

Publications (selected)

1. S Duraipandian, W Zheng, J Ng, Jeffrey Low, A Ilanacheran, Z Huang*, In vivo diagnosis of cervical precancer using Raman spectroscopy and genetic algorithm techniques, Analyst, DOI: 10.1039/c1an15296c, (2011).
2. B Lin, M Bergholt, D Lau, Z Huang*, Optical diagnosis of nasopharyngeal cancer using ultraviolet autofluorescence excitation-emission matrix spectroscopy and parallel factor analysis, Analyst, DOI: 10.1039/c1an15525c (2011).
3. M Bergholt, W Zheng, Z Huang*, Characterizing variability in in vivo Raman spectroscopic properties of different anatomical sites of normal tissue in the oral cavity, Journal of Raman Spectroscopy, DOI: 10.1002/jrs.3026 (2011).
4. X Shao, W Zheng, Z Huang*, In vivo diagnosis of colonic precancer and cancer using near-infrared autofluorescence spectroscopy and biochemical modeling, Journal of Biomedical Optics, 16(6), 067005 (2011).
5. M Bergholt, W Zheng, K Lin, K Ho, M Teh, K Yeoh, J So, Z Huang*, Combining near-infrared-excited autofluorescence and Raman spectroscopy improves in vivo diagnosis of gastric cancer, Biosensors and Bioelectronics, 26, 4104-4110 (2011).
6. M Bergholt, W Zheng, K Lin, K Ho, M Teh, K Yeoh, J So, Z Huang*, Characterizing variability in in vivo Raman spectra of different anatomical sites in the upper gastrointestinal tract toward cancer detection, J Biomedical Optics, 16(3), 037003 (2011).
7. N Lim, Z Hamed, C Yeow, C Chan, Z Huang*, Early detection of biomolecular changes in disrupted porcine cartilage using polarized Raman spectroscopy, Journal of Biomedical Optics, 16 (1), 017003 (2011).
8. M Bergholt, W Zheng, K Lin, K Ho, M Teh, K Yeoh, J So, Z Huang*, In vivo diagnosis of esophageal cancer using imageguided Raman endoscopy and biomolecular modeling, Technology in Cancer Research & Treatment, 10(2),103-112 (2011).
9. M Bergholt, W Zheng, K Lin, K Ho, M Teh, K Yeoh, J So, Z Huang*, In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques, Int J Cancer, 128(11), 2673-2680 (2011).
10. X Shao, W Zheng, Z Huang*, Polarized near-infrared autofluorescence imaging combined with near-infrared diffuse reflectance imaging for improving colonic cancer detection, Optics Express, 18 (23), 24293-24300 (2010).
11. M Bergholt, W Zheng, K Lin, K Ho, M Teh, K Yeoh, J So, Z Huang*, Raman endoscopy for in vivo differentiation between benign and malignant ulcers in the stomach, Analyst, 135 (12), 3162–3168 (2010).
12. J Lin, F Lu, W Zheng, Z Huang*, Annular aperture-detected coherent anti-Stokes Raman scattering microscopy for high contrast vibrational imaging, Applied Physics Letters, 97 (8), 083701 (2010).
13. C Yuen, W Zheng, Z Huang*, Low-level detection of anti-cancer drug in blood plasma using microwave-treated goldpolystyrene beads as surface-enhanced Raman scattering substrates, Biosensors and Bioelectronics, 26, 580-584 (2010)
14. Z Huang*, SK Teh, W Zheng, K Lin, KY Ho, M Teh, KG Yeoh, In vivo detection of epithelial neoplasia in the stomach using image-guided Raman endoscopy, Biosensors and Bioelectronics, 26, 383-389 (2010).
15. K Lin, W Zheng, Z Huang*, Integrated autofluorescence endoscopic imaging and point-wise spectroscopy for real-time in vivo tissue measurements, Journal of Biomedical Optics, 15 (4), 040507 (2010).
16. C Fang, F Lu, W Zheng, Z Huang*, Triple-frequency symmetric subtraction scheme for nonresonant background suppression in coherent anti-Stokes Raman scattering (CARS) microscopy, Optics Express, 18 (15), 15714-15724 (2010).
17. J Mo, W Zheng, Z Huang*, Fiber-optic Raman probe couples ball lens for depth-selected Raman measurements of epithelial tissue, Biomedical Optics Express, 1 (1), 17-30 (2010).
18. Z Huang*, M Bergholt, W Zheng, K Lin, K Ho, M Teh, K Yeoh, In vivo early diagnosis of gastric dysplasia using narrowband image-guided Raman endoscopy, Journal of Biomedical Optics, 15 (3), 037017 (2010).
19. J Lin, W Zheng, H Wang, Z Huang*, Effects of scatterers’ sizes on near-field coherent anti-Stokes Raman scattering under tightly focused radially and linearly polarized light excitation, Optics Express, 18(10), 10888-10895 (2010).
20. F Lu, W Zheng, J Lin, Z Huang*, Integrated coherent anti-Stokes Raman scattering and multiphoton microscopy for biomolecular imaging using spectral filtering of a femtosecond laser, Applied Physics Letters, 96(14), 133701 (2010).
21. H Li, W Zheng, Z Huang*, Rapid near-infrared fluorescence excitation-emission matrix spectroscopy for multifluorophores characterization using an acousto-optic tunable filter technique, Journal of Biomedical Optics, 15 (2), 027010 (2010).
22. SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang*, Near-infrared Raman spectroscopy for early diagnosis and typing of adenocarcinoma in the stomach, British Journal of Surgery, 97(4), 550-557 (2010).
23. SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang*, Near-infrared Raman spectroscopy for optical diagnosis in the stomach: Identification of Helicobacter-pylori infection and intestinal metaplasia, Int. J. Cancer, 126 (8), 1920-1927 (2010).
24. C Yuen, W Zheng, Z Huang*, Optimization of extinction efficiency of gold-coated polystyrene beads substrates improves surface-enhanced Raman scattering effects by post-growth microwave heating treatment, J. Raman Spectroscopy, 41 (4), 374-380 (2010).
25. J Mo, W Zheng, Jeffrey Low, J Ng, A Ilanacheran, Z Huang*, High wavenumber Raman spectroscopy for in vivo detection of cervical dysplasia, Analytical Chemistry, 81, 8908-8915 (2009).
26. J Lin, F Lu, H Wang, W Zheng, C Sheppard, Z Huang*, Improved contrast radially polarized coherent anti-Stokes Raman scattering microscopy using annular aperture detection, Applied Physics Letters, Vol. 95, No. 13, 133703 (2009).
27. F Lu, W Zheng, Z Huang*, Coherent anti-Stokes Raman scattering microscopy using tightly focused radially polarized light, Optics Letters, Vol.34, No.12, 1870-1872 (2009).
28. Z Huang*, SK Teh, W Zheng, J Mo, K Lin, X Shao, KY Ho, M Teh, KG Yeoh, Integrated Raman spectroscopy and trimodal wide-field imaging techniques for real-time in vivo tissue Raman measurements at endoscopy, Optics Letters, Vol.34, No.6, 758-760 (2009).
29. J Lin, H Wang, W Zheng, F Lu, C Sheppard, Z Huang*, Numerical study of effects of light polarization, scatterer sizes and orientations on near-field coherent anti-Stokes Raman scattering microscopy, Optics Express, 17 (4), 2423-2434 (2009).
30. SK Teh, W Zheng, David P Lau, Z Huang*, Spectroscopic diagnosis of laryngeal carcinoma using near-infrared Raman spectroscopy and random recursive partitioning ensemble techniques, Analyst, 134, 1232-1239 (2009).
31. SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang*, Near-infrared Raman spectroscopy for gastric precancer diagnosis, J. Raman Spectroscopy, 40, 908-914 (2009).
32. F Lu, W Zheng, Z Huang*, Elliptically polarized coherent anti-Stokes Raman scattering microscopy, Optics Letters, 33 (23), 2842-2844 (2008).
33. F Lu, W Zheng, Z Huang*, Phase-controlled polarization coherent anti-Stokes Raman scattering microscopy for high sensitive and high contrast molecular imaging, Journal of the Optical Society of America B, 25 (11), 1907-1913 (2008).
34. C Yuen, W Zheng, Z Huang*, Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with post-growth microwave treatment, Journal of Biomedical Optics, 13 (6), 064040 (2008).
35. C Yuen, W Zheng, and Z Huang*, Surface-enhanced Raman scattering: principles, nanostructures, fabrications and biomedical applications, J. Innovative Optical Health Sciences (JIOHS), 1 (2), 267-284 (2008).
36. F. Jaillon, W. Zheng, and Z Huang*, Half-ball lens couples a beveled fiber probe for depth-resolved spectroscopy: Monte Carlo simulations, Appl. Opt. 47, 3152-3157 (2008).
37. F Lu, W Zheng, and Z Huang*, Heterodyne polarization coherent anti-Stokes Raman scattering microscopy, Applied Physics Letters, 92 (12), 123901 (2008).
38. F Lu, W Zheng, C Sheppard, Z Huang*, Interferometric polarization coherent anti-Stokes Raman scattering microscopy, Optics Letters, 33(6), 602-604 (2008).
39. F Jaillon W Zheng, Z Huang*, Beveled fiber-optic probe couples a ball lens for improving depth-resolved fluorescence measurements of layered tissue: Monte Carlo Simulations, Phys. Med. Biol. 53, 937-951 (2008).
40. SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang*, Diagnostic potential of near-infrared Raman spectroscopy in the stomach: differentiating dysplasia from normal tissue. British Journal of Cancer, 98, 457-465 (2008).
41. SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang*, Diagnosis of gastric cancer using near-infrared Raman spectroscopy and classification and regression tree techniques, Journal of Biomedical Optics, 13 (3), 034013 (2008).
42. E Widjaja, W Zheng and Z Huang*, Classification of colonic tissues using near-infrared Raman spectroscopy and support vector machines. Int. J. Oncology, 32: 653-662 (2008).