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Roderick JE, Jessica T, Shultz LD, Brehm MA, Greiner DL, Harris MH, Silverman LB, Sallan SE, Gutierrez A, Look TA, Qi J, Bradner JE, Kelliher MA. C-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells Blood, 2014, 1040-1050
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Bandopadhayay P, Bergthold G, Nguyen B, Schubert S, Gholamin S, Tang Y, Bolin S, Schumacher SE, Zeid R, Masoud S, Yu F, Vue N, Gibson WJ, Paolella BR, Mitra SS, Cheshier SH, Qi J, Liu K, Wechsler-Reya R, Weiss WA, Swartling FJ, Kieran MW, Bradner JE, Beroukhim R, Cho Y. BET bromodomain inhibition of MYC-amplified Medulloblastoma Clinical Cancer Research, 2014, 912-925
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Cho H, Herzka T, Zheng W, Qi J, Wilkinson JE, Bradner JE, Robinson BD, Castillo-Martin M, Cordon-Cardo C, Trotman LC. RapidCap, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals Myc as a driver of Pten-mutant metastasis Cancer Discovery, 2014, 318-333
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Fiskus W, Sharma S, Qi J, Valenta JA, Schaub LJ, Shah B, Peth K, Portier BP, Rodriguez M, Devaraj SGT, Zhang M, Sheng J, Iyer SP, Bradner JE, Bhalla KN. Highly active combination of BRD4 antagonist and histon deacetylase inhibitor against human acute myeloid leukemia (AML) cells Molecular Cancer Therapeutics, 2014, in press
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Chapuy B, Mckewon MR, Lin CY, Monti S, Roemer MGM, Qi J, Raho PB, Sun HH, Yeda KT, Doench JG, Reichert E, Kung AL, Rodig SJ, Young RA, Shipp MA, Bradner JE Discovery and characterization of superenhancer-associated dependencies in diffuse large B cell lymphoma Cancer Cell, 2013, 777-790
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Anders L, Guenther MG, Qi J, Fan ZP, Marineau JJ, Rahl PB, Loven J, Sigova AA, Smith WB, Lee TI, Bradner JE, Young RA Genome-wide localization of small molecules Nature Biotechnology, 2014, 92-96
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Wu X, Qi J, Bradner JE, Xiao G, Chen L Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling Journal of Biological Chemistry, 2013, 36094-36105
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Shimamura T, Chen Z, Soucheray M, Carretero J, Kikuchi E, Tchaicha JH, Gao Y, Cheng KA, Cohoon TJ, Qi J, Akbay E, Kimmelman AC, Kung AL, Bradner JE, Wong KK. Efficacy of BET bromodomain inhibition in Krasmutant non-small cell lung cancer Clinical Cancer Research, 2013, 6183-6192
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Spiltoir, JI, Stratton MS, Cavasin MA, Demos-Davis K, Reid BG, Qi J, Bradner JE, McKinsey TA. BET acetyllysine binding proteins control pathological cardiac hypertrophy Journal of Molecular and Cellular Cardiology, 2013, 175-179
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Anarnd P, Brown JD, Lin CY, Qi J, Zhang R, Artero-Calderon P, Ailati A, Bullard J, Alazem K, Margulies KB, Cappola TP, Lemieux M, Plutzky J, Bradner JE, Haldar SM. BET bromodomains mediate transcriptional pause release in heart failure Cell, 2013, 569-582
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Frumm SM, Fan ZP, Ross KN, Duvall JR, Jeremy R, Gupta S, Verplank L, Suh BC, Holson E, Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J, Roti G, Kung AL, Bradner JE, Toliday N, Stegmaier K. Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation Chemistry & Biology, 2013, 713-725
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Puissant A, Frumm SM, Alexe G, Bassil CF, Qi J, Chanthery YH, Nekritz EA, Zeid R, Gustafson WC, Greinger P, Garnett MJ, McDermott U, Benes CH, Kung AL, Weiss WA, Bradner JE, Stegmaier K. Targeting MYCN in neuroblastoma by BET bromodomain inhibition Cancer Discovery, 2013, 308-323
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Yu W, Chory EJ, Wernimont AK, Tempel W, Scopton A, Federation A, Marineau JJ, Qi J, Barsyte-Lovejoy D, Yi J, Marcellus R, Iacob, RE, Engen JR, Griffin C, Aman A, Wienholds E, Li F, Pineda J, Estiu G, Shatseva T, Hajian T, Al-awar R, Dick JE, Vedadi M, Brown PJ, Arrowsmith CH, Bradner JE, Matthieu S. 2012 Catalytic site remodeling of the DOT1L methyltransferase by selective inhibitors Nature communication, 2012, 2304/1-2304/11
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Ott CJ, Kopp N, Bird L, Paranal RM, Qi J, Bowen T, Rodig SJ, Kung AL, Bradner JE, Weinstock DM BET bromodomain inhibition targets both c-MYC and IL7R in high-risk acute lymphoblastic leukemia. Blood, 2012 2843-2852
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Filippakopoulos P, Qi J (Co-First author), Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, West N, Cameron MJ, Heightman TD, Thangue NL, Kung AL, French CA, Wiest O, Knapp S, Bradner JE. Selective inhibition of BET bromodomains Nature, 2010, 1067-1073
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Movassaghi M, Tjandra M, Qi J. “Total synthesis of (-)-Himandrine” Journal of the American Chemical Society 2009, 9648
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Trullinger T, Qi J, Roush WR. “Studies on the synthesis of quatromicins A3 and D3: synthesis of the vertical and horizontal bis-spirotetranate fragments” The Journal of Organic Chemistry, 2006, 6915