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Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z, “The Design, Synthesis and Biological Evaluations of C-6 or C-7 Substituted 2-Hydroxylisoquinoline-1,3-diones as Inhibitors of Hepatitis C Virus” Bioorganic & Medicinal Chemistry, 20: 467–479 (2012).
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Palpant NJ, Houang EM, Mundada L, Sham YY, Metzger JM “pH responsive titratable performance of histidine-modified cardiac troponin I attributed to imidazole ionization” Biophysical Journal, 102: 1570-1579 (2012).
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Li L, Sham YY, Elmquist WF “pH dependent transport of premetrexed in breast cancer resistant protein” Drug Metabolism and Disposition, 39: 1478-1485 (2011).
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Tang J, Maddali K, Metifiot M, Sham YY, Vince R, Pommier Y, Wang Z “3-Hyroxypyrimidine-2,4-diones as novel scaffold for HIV integrase inhibitor design” Journal Medicinal Chemistry, 54:2282-2292 (2011).
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Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z “N-3 hydroxylation of pyrimidine-2,4-diones yields dual inhibitors of HIV reverse transcriptase and integrase” ACS Medicinal ChemistryLetters, 2: 63-67 (2011).
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Chen L, Wilson DJ, Xu Y, Aldrich CC, Felczak K, Sham YY, Pankiewicz K “Triazole-linked inhibitors of inosine monophosphate dehydrogenases from human and Mycobacterium tuberculosis” Journal Medicinal Chemistry, 53: 4768-4778 (2010).
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Tang J, Maddali K, Pommier Y, Sham YY, Wang Z “Scaffold rearrangement of dihydroxypyrimidine integrase inhibitors: Binding model revisited” Bioorganic & Medicinal Chemistry Letters, 20:2037-2048 (2010).
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Ding L, Sham YY, Vince R “Design, asymmetric synthesis and bioevaluation of pseudo-symmetric sulfoximine inhibitors against HIV-1 protease” Bioorganic & Medicinal Chemistry, 18: 2037-2048 (2010).
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Petrelli R, Sham YY, Chen L, Felczak K, Bennett EM, Aldrich C, Wilson DW, Yu JS, Cappellacci L, Franchetti P, Grifantini M, Mazzola F, Di Stefano M, Magni G, Pankiewicz K “Selective inhibition of NAD kinase by dinucleoside disulfide NAD mimics” Bioorganic & Medicinal Chemistry, 17:5656-5664 (2009).
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Nesmelova IV, Sham Y, Gao J, Mayo KH “CXC and CC Chemokines from mixed heterodimers: Association free energies from MD simulations and experimental correlations” Journal of Biological Chemistry, 283: 24155-24166 (2008).
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Chou T, Sham YY, Wagner CR "The C-terminal loop of histidine triad nucleotide binding protein 1 (Hint1) mediates substrate specificity" Biochemistry, 46:13074-13079 (2007).
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Li M, He Z, Ermakova S, Zheng D, Tang F, Cho YY, Zhu F, Ma WY, Sham Y, Rogozin EA, Bode AM, Cao Y, Dong Z "Direct inhibition of insulin-like growth factor-1 receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell proliferation and transformation" Cancer Epidemiology Biomarkers & Prevention, 16: 598-605 (2007).
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Xing C, Wang L, Tang X, Sham YY “Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1” Bioorganic & Medicinal Chemistry, 15:2167-2176 (2007).
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Kumar V, Locuson C, Sham Y, Tracy T “Amiodarone-analog dependent effects on CYP2C9-mediated metabolism and kinetic profiles” Drug Metabolism and Disposition, 34: 1688-1696 (2006).
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Zhang Y, Sham YY, Rajamani R, Gao J, Portoghese PS “Homology modeling of the mu opioid receptor built in a complete membrane-aqueous system” ChemBioChem, 6: 853-859 (2005).