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Biography

Prof. Dominique Shum-Tim

Royal Victoria Hospital, Canada


Email: dshumtim@yahoo.ca


Qualifications

1990-1994 M.Sc., Experimental Surgery, McGill University, Canada

1984-1988 M.D., Faculty of Medicine, McGill University, Canada


Publications

  1. Atoui R, Mohammadi S, Shum-Tim D.: Surgical Extraction of Occluded Stents: When stenting becomes a problem. Interact Cardiovasc Thorac Surg. 2009 Oct;9(4):736-8. Epub 2009 Jul 29.
  2. Shum-Tim D. Invited Commentary: Pulmonary artery banding for functionally single ventricles with unobstructed pulmonary blood flow: The impact of tighter banding and evaluation of current strategies in the staged Fontan era. Ann Thorac Surg Ann Thorac Surg. 2010 Jan;89(1):179-80.
  3. Chen G, Nayan M, Duong M, Asenjo JF, Ge Y, Chiu RC-J, Shum-Tim D.: Marrow stromal cells for cell-based therapy: The role of anti-inflammatory cytokines in cellular cardiomyoplasty. Ann Thorac Surg. 2010 Jul;90(1):190-7.
  4. Al-Kindi A, Asenjo JF, Chen G, Ge Y, Bhathena J, Chiu RC-J, Prakash S, Shum-Tim D.: Cellular Cardiomyoplasty: Optimizing Cellular Dosage and Retention by Microencapsulation. Eur J Cardiovasc Thorac Surg. 2011 Jan;39:241-7.
  5. Paul A, Shum-Tim D, Prakash S.: Investigation of PEG Integrated Alginate-chitosan Microcapsule for Stem Cell Delivery Using Baculovirus Transduced Marrow Stromal Cells. Cardiovasc Eng and Tech. Volume 1, Number 2, 154-164, DOI: 10.1007/s13239-010-0017-3.
  6. Paul A, Khan AA, Shum-Tim D, Prakash S.: BacMam virus transduced cardiomyoblasts can be used for myocardial transplantation using AP-PEG-A microcapsules: molecular cloning, preparation and in vitro analysis. J Biomed Biotechnol. 2010:858094. Epub 2011 Jan 19.
  7. Paul A, Cantor A, Shum-Tim D, Prakash S.: Superior Stem Cell Delivery Features of Genipin Crosslinked Polymeric Microcapsules: Preparation and in vitro characterization using human adipose stem cells. Mol Biotechnol. 2010 Nov 30. [Epub ahead of print].
  8. Hatzakorzian R, Carvalho G, Bui H, Sato T, Wykes L, Shum-Tim D.: Schricker T.: Highdose Insulin Administration is Associated with Hypoaminoacidemia During Cardiac Surgery. Metabolism, 2011 (in press).
  9. Nayan M, Paul A, Chen G, Chiu R, Prakash S, Shum-Tim D.: Superior Therapeutic Potential of Young Marrow Stromal Cells by Direct Intramyocardial Delivery in Aged Recipients with Acute Myocardial Infarction: In vitro and in vivo investigation. J Tissue Eng, 2011 (in press).
  10. Paul A, Srivastava S, Chen G, Shum-Tim D, Prakash S.: Functional Assessment of Adipose Stem Cells as an Efficient Alternative to Marrow Stem Cell for Xenotransplantation in Cardiovascular Diseases: In-vitro and in-vivo studies in myocardial infracted immunocompetent model. Cell Biochem and Biophysics, 2011 (in press).
  11. Nayan M, Paul A, Chen G, Chiu RC-J, Prakash S, Shum-Tim D.: Superior Therapeutic Potential of Young Bone Marrow Mesenchymal Stem Cells by Direct Intramyocardial Delivery in Aged Recipients with Acute Myocardial Infarction: In-vitro and in-vivo investigation. J Tissue Eng, 2011 (in press).
  12. Paul A, Chen G, Khan AA, Vijayaraghava TS, Shum-Tim D, Prakash S.: Genipin-Crosslinked Microencapsulated Human Adipose Stem Cells Augment Transplant Retention Resulting in Attenuation of Chronically Infracted Rat Heart Fibrosis and Cardiac Dysfunction. Cell Transplantation, 2011 (submitted).
  13. Paul A, Binsalamah Z, Khan AA, Abbasi S, Elias CB, Shum-Tim D, Prakash S.: A Novel Nanobiohybrid Complex of Recombinant Baculovirus and Tat/DNA Nanoparticles for Efficient Gene Delivery: Implication in myocardial infarction therapy using Ang-1 transgene. Biomaterials, 2011 (submitted).
  14. Paul A, Nayan M, Khan AA, Shum-Tim D, Prakash S.: Hybrid Nanocomplex of Baculovirus and TAT/DNA Nanoparticles as a Novel Gene Delivery Vehicle for Adipose Stem Cell-gene Therapy: Functional assessment in myocardially infracted rat model. Nanomedicine, 2011 (submitted).
  15. Paul A, Shao W, Abbasi S, Binsalamah Z, Shum-Tim D, Prakash S.: PAMAM Dendrimer-Baculovirus Hybridized Nanocomplex for Adipose Stem Cell Based Gene Therapy: Functional assessment in myocardial therapy using PEG surface functionalized microcapsule formulation. Molecular Pharmaceutics, 2011.