Biography

Dr. Yohichi Kumaki

Utah State University, USA


E-mail: yohichi.kumaki@usu.edu, yangdawei62@hotmail.com


Qualifications

1995 Ph.D., Gunma University School of Medicine, Gunma, Japan

1985 M.D., Second Military Medical University, Shanghai, P. R. China


Publications (Selected)

  1. Kumaki, Y., Ennis, J., Rahbar, R., Turner, J.D., Wandersee, M.K., Bailey, K.W., Smith, A.J., Vest, Z.G., Madsen, J.R., Li, J.K., Barnard, D.L. Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse model.
  2. Kumaki, Y., Wandersee, M.K., Bailey, K.W., Smith, A.J., Vest, Z.G., Nelson, N.M., Li, J.K., Smee, D.F., Barnard, D.L. Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin.
  3. Kumaki, Y., Day, C.W., Wandersee, M.K., Madsen, J.R., Woolcott, J.D., Hoopes, J.D., Bailey, K.W., Wong, M.H., Smee, D.F., Barnard, D.L. Induction of interferon gamma inducible protein 10 by SARS-CoV infection, interferon alfacon 1 and interferon inducer in human bronchial epithelial Calu-3 cells and BALB/c mice. Antivir. Chem. Chemother., 2010: 20: 169-77.
  4. Day, C.W., Baric, R., Cai, S.X., Frieman, M., Kumaki, Y., Morrey, J.D., Smee, D.F., Barnard, D.L. A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo. Virology, 2009: 395: 210-220.
  5. Barnard, D.L. and Kumaki, Y. Development in the search for small molecule inhibitors for treatment of severe acute respiratory syndrome coronavirus. Antiviral Research: Strategies in Antiviral Drug Discovery Edited by R. L. LaFemina 2009 ASM Press, Washington, DC., Chapter 12, 209-222.
  6. Kumaki, Y., Day, C.W., Wandersee, M.K., Schow, B.P., Madsen, J.S., Grant, D., Roth, J.P., Smee, D.F., Blatt, L.M., Barnard, D.L. Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells. Biochem. Biophys. Res. Commun., 2008, 371, 110-113.
  7. Kumaki, I., Yang, D., Koibuchi, N., Takayama, K. Neuronal expression of nuclear transcription factor MafG in the rat medulla oblongata after baroreceptor stimulation. Life Sci., 2006, 78, 1760-1766.
  8. Kumaki, Y., Kumaki, I., Guo, X.M., Shang, W.L., Koyama, T., Okamura, A., Shiba, Y., Mukaiyama, T., Sasaki, N., Kodama, M. Long-term culture of primary porcine mature hepatocytes in the medium supplemented with ascorbic acid 2-phosphate. (Natural Science in press).
  9. Yang, D-W., Shuda, M., Kaji, H. Inhibition of human T-cell leukemia virus type I by the short oligoguanylic acids in vitro. Mater. Sci. Eng. C., 2004, 24, 887-892.
  10. Yang, D-W., Koyama, T., Okamura, A., Shiba, Y., Kodama, M. Ascorbic acid 2-phosphate enhances the albumin mRNA expression and secretion of porcine hepatocytes. Mater. Sci. Eng. C., 2004, 24, 323-327.
  11. Yang, D-W., Fujii, N., Takata, T., Shimo-Oka, T., Tajima, S., Tanaka, Y., Saito, T. Expression of human D-beta aspartate in the lens-derived cell lines. Mol. Vision, 2003, 9, 200-204.
  12. Fu, D-X., Haraguchi, Y., Jinno, A., Yang, D-W., Hoshino, H. Identification of membrane antigens important for adsorption of human T-cell leukaemia virus type I. Res. Virol., 1998, 149, 383-392.
  13. Yang, D-W., Iwai, H., Yamamoto, A., Hoshino, H., Fu, D. Effect of phospholipid and phospholipase on adsorption of human T-cell leukemia virus type 1. Biochem. Biophys. Acta, 1997, 1349, 25-32.
  14. Yang, D-W., Ohta, Y., Yamaguchi, S., Tsukada, Y., Haraguchi, Y., Hoshino, H., Amagai, H., Kobayashi, S. Sulfated colominic acid: an antiviral agent that inhibits the infectivity of human immunodeficiency virus type 1 in vitro. Antiviral Res., 1996, 31, 95-104.
  15. Haraguchi, Y., Yang, D-W., Handa, A., Shimizu, N., Tanaka, Y., Hoshino, H. Detection of neutralizing antibody against human T-cell leukemia virus type 1 in a cell-free infection system using polymerase chain reaction. Int. J. Cancer, 1994, 59, 1-6.
  16. Yang, D-W., Haraguchi, Y., Iwai, H., Handa, A., Shimizu, N., Hoshino, H. Inhibition of adsorption of human T-cell leukemia virus type 1 by a plant lectin, wheat germ agglutinin. Int. J. Cancer, 1994, 56, 100-105.
  17. Miyoshi, I., Takehara, N., Sawada, T., Iwahara, Y., Yang, D-W., Hoshino, H., Kataoka, R. Immunoglobulin prophylaxis against HTLV-1 in a rabbit model. Leukemia, 1992, 6, 24-26.
  18. Kataoka, R., Takehara, N., Iwahara, Y., Sawada, T., Ohtsuki, Y., Yang, D-W., Hoshino, H., Miyoshi, I. Transmission of HTLV-1 by blood transfusion and its prevention by passive immunization in rabbits. Blood, 1990, 76, 1657-1661.
  19. Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin, 23nd International Conference on Antiviral Research, San Francisco, California, USA, pp36, (2010).
  20. Prophylactic efficacy of intranasally administered HSP nanoparticles for treating a lethal SARS-CoV infection in BALB/c mice, 22nd International Conference on Antiviral Research, Miami, Florida, USA, pp32, (2009).
  21. Induction of interferon gamma inducible protein 10 by SARS-CoV infection, interferon alfacon 1 and interferon inducer in human bronchial epithelial Calu-3 cells and BALB/c mice, 22nd International Conference on Antiviral Research, Miami, Florida, USA, pp34, (2009).
  22. Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells, Intermountain Branch Annual Conference of American Society for Microbiology, Logan, Utah, USA, pp.20, (2008).
  23. Biological and medical applications of novel synthetic chemokine analogs, 19th American Peptides Symposium, San Diego, California, USA, pp.173, (2005).
  24. Chemical biology and biomedical applications of synthetic molecules targeted to apoptosis regulated by the Bcl-2 family, 19th American Peptides Symposium, San Diego, California, USA, pp.178, (2005).
  25. Chemically engineered SMM-Chemokines as probes and inhibitors of HIV-associated neuronal apoptosis, 19th American Peptides Symposium, San Diego, California, USA,pp.179, (2005).
  26. Baroreceptor stimulation expressed transcription factor MafG in neurons in the rat medulla oblongata, 81th Annual Meeting of the Physiological Society of Japan, Sapporo, Japan, pp.177, (2004).
  27. Effect of ascorbic acid 2-phosphate on porcine mature hepatocytes, 2nd Japanese Conference on Regenarative Medicine, Kobe, Japan, pp. 149, (2003).
  28. Ascorbic acid 2-phosphate enhances the albumin mRNA expression and secretion of porcine hepatocytes, 9th Research Meeting of Liver Cells, Akita, Japan, pp. 48, (2002).
  29. Expression of human D-beta aspartate in the lens-derived cell line. 26th Annual Meeting of Japanese Society for Study of Origin and Evolution Life, Osaka, Japan. pp. 39, (2001).
  30. Inversion and isomerization of Asp-151 residue in human alpha-A crystallin from normal and cataractous lenses, XIV International Congress of Eye Research, Santa Fe, New Mexico, pp. 137, (2000).
  31. Single amino acid substitution in the gp120 V3 loop change the cell tropism, also alter cytopathic properties of HIV-1, Third Asia-Pacific Congress of Medical Virology, Beijing, China, pp.110, (1994).
  32. Analysis of high infectivity of cell-free HTLV-1 derived from kidney cell line, Forty-1st Japanese Conference of Medical Virology, Sapporo, Japan, pp. 132, (1993).
  33. Effects of polycations on infection with human retroviruses, Tenth International Conference on AIDS, Yokohama, Japan, pp. 114, PA 0337 (1994).
  34. Identification of membrane antigens important for adsorption of human T-cell leukaemia virus type I. Third Asia-Pacific Congress of Medical Virology, Beijing, China, pp.129, (1994).Sulfated colominic acid: an antiviral agent that inhibits the infectivity of human immunodeficiency virus type 1 in vitro, Tenth International Conference on AIDS, Yokohama, Japan, pp. 114, PA 0337 (1994).
  35. Effect of phospholipid and phospholipase on adsorption of human T-cell leukemia virus type 1. Forty-ninth Japanese Conference of Cancer Research, Sapporo, Japan, pp. 116, (1990); Thirty-ninth Japanese Conference of Medical Virology, Fukuoka, Japan, pp. 75, (1991); Third Asia-Pacific Congress of Medical Virology, Beijing, China, pp.129, (1994).
  36. Detection of neutralizing antibody against human T-cell leukemia virus type 1 in a cell-free infection system using polymerase chain reaction, Fourtyth Japanese Conference of Medical Virology, Kobe, Japan, pp. 85, (1992).
  37. Inhibition of adsorption of human T-cell leukemia virus type 1 by a plant lectin, wheat germ agglutinin, Thirty-ninth Japanese Conference of Medical Virology, Fukuoka, Japan, pp. 75, (1991).


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