Prof. Maria do Ceu Goncalves da Costa

National Laboratory of Energy and Geology, Portugal

Email: c_eu_costa@hotmail.com, ceu.costa@lneg.pt

Qualifications

2007 - 2008 Post Graduation, Instituto Superior de Gestão Rua Vitorino Nemésio, Management and Economy for Public Sector

1987 - 1993 Doctor, Faculdade de Farmácia de Lisboa Av. Professor Gama Pinto, Philosophy

1985 - 1986 Master, Universidade Nova de Lisboa Monte da Caparic, Sciencea

1979 - 1981 Degree in Pharmacy, Faculdade de Farmácia de Lisboa Av. Professor Gama Pinto

Publications (Selected)

1. Maria C. Costa, Susana G. Teixeira, Cristina Rodrigues, Pedro Ryberg Figueiredo, Maria J. Marcelo Curto New Synthesis of (-)-Thioambrox, Tetrahedron, 61, 4403-4407, 2005.
2. Ferrari, B.; Castilho, P.C.; Tomi, F.; Rodrigues, AI.; Costa, M.C. and Casanova, J., Direct Identification and Quantitative Determination of Costunolide and Dehydrocostuslactone in Laurus novocanariensis Fixed Oil using 13C-NMR Spectroscopy, Phytochem. Anal., 16, 104-107, 2005.
3. L. Santos, S. Santos, M.A. Medeiros, M.C. Costa, R. Tavares, M.J.M. Curto, NMR STUDIES of Some Rifamycins, Journal of Molecular Structure, 563-564 (2001), 61-78.
4. Castilho, P.C.; Costa, M.C.; Rodrigues, A.I.; Branco, P.; Costa, M., Characterization of Triacylglycerols in Madeira Laurel Oil by HPLC-APCI-MS, J. Am Oil Chem. Soc., 81, 913-919, 2005.
5. Paula C. Castilho, Maria do Céu Costa, Ana Rodrigues, and Ana Partidário, Characterization of Laurel Fruit Oil from Madeira Island, Portugal, J. Am Oil Chem. Soc., JAOCS 82, 863–868, 2005.
6. Leonel Rojo, Julio Benites Ana Rodrigues, Florência Venâncio, Luis Ramalho, Adriano Teixeira, Sónia Feio and Maria do Céu.Costa, ,Composition and Antimicrobial Screening of the Essential Oil of Acantholippia deserticola (Phil.ex F. Phil.) Moldenke, Journal of Essential Oil Research, 18, 695-697, 2006.
7. M. Céu Costa, Susana P. Alves, M. Eduarda Correia, M. Regina Tavares, M. João Marcelo-Curto, Synthesis of an Ambergris-Type Ketal from Abietic Acid, Synthesis, 7, 1171-1175, 2006.
8. M. Inês Passos Eleutério, Jörg Schimmel, Gerd Ritter, Maria do Céu Costa, and Richard R. Schmidt, Synthesis of Saponins with Allobetulin and Gylcyrrhetic Acid as Aglycones, Eur. J. Org. Chem., 5293-5304, 2006.
9. Susana S. Ramos, Paulo Almeida, Lina Santos, William B. Motherwell, Tom D. Sheppard and Maria do Céu Costa, Functionalization of Terpenoids at C-4 via Organopalladium Dimers. Cyclopropane Formation During Oxidation of Homoallylic σ-Organopalladium Intermediates with Lead Tetraacetate, Tetrahedron, 63, 12608-12615, 2007.
10. S. S. Ramos, L. Ramalho, M. Costa, A. Teixeira, P. Almeida, M. C. Costa, Mass Spectrometric Analysis of Epimeric 3α/3β Functionalized Steroids, ARKIVOC (xiv), 163-171, 2007.
11. Ricardo Figueiredo, Ana I. Rodrigues and M. do Céu Costa, Volatile Composition of Red Clover (Trifolium pratense L.) Forages in Portugal – The Influence of Ripening Stage and Ensilage, Food Chemistry, 104 (2007), 1445 – 1453.
12. Luna-Herrera, J., Costa, M.C., González, H.G., Rodrigues, A.I and Castilho, P.C., Synergistic Antimycobacterial Activities of Sesquiterpene Lactones from Laurus spp, Journal of Antimicrobial Chemotherapy 2007 59(3): 548-552.
13. Alexandra Paulo, Sofia Martins, Pedro Branco, Teresa Dias, Carlos Borges, Ana Isabel Rodrigues, Maria do Céu Costa, Adriano Teixeira and Hélder Mota-Filipe, The opposing effects of the flavonoids isoquercitrin and Sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats, Phytother. Res. 22, 539–543, 2008.
14. Ricardo Figueiredo, Cristina Moiteiro, M. Augusta Medeiros, P. Almeida da Silva, D. Ramos, F. Spies, M.O. Ribeiro, M. Cristina S. Lourenço, I.N. Júnior, M. Manuela Gaspar, Eugénia Cruz, M. João Marcelo Curto, Franzblau S.G., H. Orozco E., D Aguilar L, R. Hernandez Pando and M. Céu Costa, “Synthesis and evaluation of rifabutin analogs against Mycobacterium avium and H37Rv, MDR and NRP Mycobacterium tuberculosis”, Bioorg Med Chem. 2009 Jan 15;17(2):503-11. Epub 2008 Dec 10.
15. Meisel ML, do Céu Costa M., Pena A., Regulatory approach on environmental risk assessment. Risk management recommendations, reasonable and prudent alternatives. Ecotoxicology.,2009 Nov;18(8): 1176-81.
16. Jan Rijn Zeevaart, Judith Marie Wagener, Maria Neves, Maria Ceu Costa, Cristina Rodrigues, Mildred Dithebe, Elmare´ Kilian and Ignacy Cukrowski, 99mTc-labelled biguanide derivatives: chemical speciation modelling thereof and evaluation in vervets, J Radioanal Nucl Chem (2010) 283:123–131.
17. Julio Benites, Eunices Gutierrez, José López, Mauricio Rojas, Leonel Rojo, Maria do Céu Costa, Maria Pilar Vinardell and Pedro Buc Calderon, Evaluation of Analgesic Activities of Tremetone Derivatives Isolated from the Chilean Altiplano Medicine Parastrephia lepidophylla, Natural Product Communications, Vol. 7, No. 5, 611 - 614 (2012).
18. Ricardo Figueiredo, Daniela F. Ramos, Cristina Moiteiro, Maria Augusta Medeiros, Maria João Marcelo Curto, José Cardoso de Menezes, Rogelio Hernandez Pando, Pedro E. A. Silva and Maria do Céu Costa, Pharmacophore insights into rpoB gene mutations in Mycobacterium tuberculosis rifampicin resistant isolates, European Journal of Medicinal Chemistry, 47 186 -193 (2012).