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Prof. Claire Louise Gibson

University of Leicester, UK

Email: cg95@le.ac.uk


2000 Ph.D., University of Newcastle upon Tyne

1996 B.Sc., University of Sheffield

Publications (Selected)

  1. Gibson CL, Coomber B, Murphy SP (2011) Progesterone is neuroprotective following cerebral ischemia in reproductively aging female mice. Brain, 134: 2125-2133.
  2. Davidson C, Coomber B, Gibson CL, Young AMJ (2011) Effect of pre-ischaemic conditioning on hypoxic depolarization of dopamine efflux in the rat caudate brain slice measured in real-time with fast cyclic voltammetry. Neurochemistry International (In Press).
  3. Davidson C, Chauhan NK, Knight S, Gibson CL, Young AMJ (2011) Modelling ischaemia in vitro: effects of temperature and glucose concentration on dopamine release evoked by oxygen and glucose depletion in a mouse brain slice model of ischaemic brain damage. Journal of Neuroscience Methods (In Press).
  4. Coomber B, Gibson CL (2010) Sustained levels of progesterone prior to the onset of cerebral ischemia are not beneficial to female mice. Brain Research, 1361: 124-132.
  5. Gibson CL, Murphy SP (2010) Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies. Journal of Neurochemistry, 115: 806-813.
  6. Gibson CL, Bath PMW, Murphy SP (2010) G-CSF administration is neuroprotective following transient cerebral ischemia even in the absence of a functional NOS-2 gene. Journal of Cerebral Blood Flow and Metabolism, 30: 739-743.
  7. England TJ, Gibson CL, Bath PMW (2009) Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review. Brain Research Reviews, 62: 71-82.
  8. Gibson CL, Coomber B, Rathbone J (2009) Is progesterone a candidate neuroprotective treatment following ischemic stroke? The Neuroscientist, 15: 324-332.
  9. Gibson CL, Gray LJ, Bath PMW, Murphy SP (2008) Progesterone for the treatment of experimental brain injury: a systematic review. Brain, 131: 318-328.
  10. Murphy S & Gibson CL (2007) Nitric oxide, ischaemia and brain inflammation. Biochemical Society Transactions, 35: 1133-1137.
  11. Sun Y, Alexander SPH, Garle MJ, Gibson CL, Hewitt K, Murphy SP, Kendall DA & Bennett AJ (2007) Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism. British Journal of Pharmacology, 152: 734-743.
  12. Gibson, CL, Gray, L, Murphy, SP, Bath, PMW (2006) Estrogen for experimental ischemic stroke; a systematic review. J Cereb Blood Flow Metab, 26: 1103-1113.
  13. Gibson, CL, Jones, NC, Prior, MJW, Bath, PMW & Murphy SP (2005) G-CSF suppresses edema formation and reduced interleukin-1 beta expression following cerebral ischemia in mice. J Neuropath Exp Neurol, 64: 763-769.
  14. Gibson, CL, Constantin, DC, Prior, MJW, Bath, PMW & Murphy SP (2005) Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia. Exp Neurol. 193: 522-530.
  15. Gibson, CL, Coughlan, TC, & Murphy, SP (2005) Glial Nitric Oxide and Ischemia. Glia, 50: 417-426 (Invited review).
  16. Gibson, CL, Bath, PMW & Murphy, SP (2005) G-CSF promotes functional recovery following middle cerebral artery occlusion in male mice. J Cereb Blood Flow Metab, 25: 431-439.
  17. Coughlan, T, Gibson, CL & Murphy, SP (2005) Modulatory effects of progesterone on NOS-2 expression in vivo and in vitro. J. Neurochem. 93: 932-942.
  18. Willmot, M, Gibson, CL, Gray, L, Murphy, SP, Bath, PMW (2005) Nitric oxide synthase inhibitors in experimental stroke and their effects on infarct size and cerebral blood flow; a systematic review. Free Radical Biology and Medicine, 39: 412-435.
  19. Willmot, M, Gray, L, Gibson, CL, Murphy, SP & Bath, PMW (2005) Systematic review of nitric oxide donors and L-arginine in experimental stroke: effects on infarct size and cerebral blood flow. Nitric Oxide, 12: 141-149.