Pharmacology & Pharmacy

Vol.8 No.5(2017), Paper ID 76318, 18 pages

DOI:10.4236/pp.2017.85012

 

Clonidine Inhibits Phenylephrine-Induced Contraction of Rat Thoracic Aortae by Competitive Antagonism of α1-Adrenoceptors Independent of α2-Adrenoceptor Stimulation

 

Daisuke Chino, Mai Naramatsu, Keisuke Obara, Yoshio Tanaka

 

Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan

 

Copyright © 2017 Daisuke Chino, Mai Naramatsu, Keisuke Obara, Yoshio Tanaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

How to Cite this Article


Chino, D. , Naramatsu, M. , Obara, K. and Tanaka, Y. (2017) Clonidine Inhibits Phenylephrine-Induced Contraction of Rat Thoracic Aortae by Competitive Antagonism of α1-Adrenoceptors Independent of α2-Adrenoceptor Stimulation. Pharmacology & Pharmacy, 8, 172-188. doi: 10.4236/pp.2017.85012.

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