Open Journal of Inorganic Chemistry

Vol.6 No.2(2016), Paper ID 66188, 9 pages

DOI:10.4236/ojic.2016.62010

 

Cu(II) Benzoylpyridine Thiosemicarbazone Complexes: Inhibition of Human Topoisomerase IIα and Activity against Breast Cancer Cells

 

Jennifer D. Conner, Wathsala Medawala, Madison T. Stephens, William H. Morris, Joseph E. Deweese, Patrick L. Kent, Jeffery J. Rice, Xiaohua Jiang, Edward C. Lisic

 

Department of Chemistry, Tennessee Technological University, Cookeville, TN, USA
Department of Chemistry, Tennessee Technological University, Cookeville, TN, USA
Department of Chemistry, Tennessee Technological University, Cookeville, TN, USA
Department of Chemistry, Tennessee Technological University, Cookeville, TN, USA
Department of Pharmaceutical Sciences, Lipscomb University, Nashville, TN, USA
Department of Chemical Engineering, Tennessee Technological University, Cookeville, TN, USA
Department of Chemical Engineering, Tennessee Technological University, Cookeville, TN, USA
Department of Chemistry, Tennessee Technological University, Cookeville, TN, USA
Department of Chemistry, Tennessee Technological University, Cookeville, TN, USA
Department of Biochemistry, Vanderbilt University, Nashville, TN, USA

 

Copyright © 2016 Jennifer D. Conner, Wathsala Medawala, Madison T. Stephens, William H. Morris, Joseph E. Deweese, Patrick L. Kent, Jeffery J. Rice, Xiaohua Jiang, Edward C. Lisic et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

How to Cite this Article


Conner, J. , Medawala, W. , Stephens, M. , Morris, W. , Deweese, J. , Kent, P. , Rice, J. , Jiang, X. and Lisic, E. (2016) Cu(II) Benzoylpyridine Thiosemicarbazone Complexes: Inhibition of Human Topoisomerase IIα and Activity against Breast Cancer Cells. Open Journal of Inorganic Chemistry, 6, 146-154. doi: 10.4236/ojic.2016.62010.

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