Open Journal of Medicinal Chemistry
Vol.5 No.1(2015), Paper ID 54947, 14
pages
DOI:10.4236/ojmc.2015.51002
Novel Cytocidal Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl) Benzenesulfonates and Benzenesulfonamides with Affinity to the Colchicine-Binding Site: Is the Phenyl 2-Imidazolidinone Moiety a New Haptophore for the Design of New Antimitotics?
Sébastien Fortin, Lianhu Wei, Lakshmi P. Kotra, René C.-Gaudreault
Unité des Biotechnologies et de Bioingénierie, Centre de Recherche du CHU de Québec, Hôpital Saint-François d’Assise, Université Laval, Québec, Canada
Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada
Center for Molecular Design and Preformulations, Toronto General Research Institute, University Health Network, Toronto, Canada
Département de Médecine Moléculaire, Faculté de Médecine, Université Laval, Pavillon Vandry, Québec, Canada
Faculté de Pharmacie, Université Laval, Pavillon Vandry, Québec, Canada
Copyright © 2015 Sébastien Fortin, Lianhu Wei, Lakshmi P. Kotra, René C.-Gaudreault et al. This is
an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any
medium, provided the original work is properly cited.
How to Cite this Article
Fortin, S. , Wei, L. , Kotra, L. and C.-Gaudreault, R. (2015) Novel Cytocidal Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl) Benzenesulfonates and Benzenesulfonamides with Affinity to the Colchicine-Binding Site: Is the Phenyl 2-Imidazolidinone Moiety a New Haptophore for the Design of New Antimitotics?.
Open Journal of Medicinal Chemistry,
5, 9-22. doi:
10.4236/ojmc.2015.51002.